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Article

MicroRNA expression profiles in benign prostatic hyperplasia

  • Authors:
    • Nan Zhang
    • Zhongyi Li
    • Fuding Bai
    • Na Ji
    • Yichun Zheng
    • Yi Li
    • Jimin Chen
    • Xiawa Mao
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China, Department of Anesthesia, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China
  • Pages: 3853-3858
    |
    Published online on: December 19, 2017
       https://doi.org/10.3892/mmr.2017.8318
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Abstract

Although alterations in microRNA (miRNA) expression have been previously investigated prostate cancer, the expression of miRNAs specifically in benign prostate hyperplasia (BPH) of the prostatic stroma remains to be fully elucidated. In the present study, miRNAs and gene expression profiles were investigated using microarray analysis and reverse transcription quantitative‑polymerase chain reaction (RT‑qPCR) in BPH tissue to clarify the associations between miRNA expression and target genes. Prostate tissue samples from five patients with BPH and five healthy men were analyzed using human Affymetrix miRNA and mRNA microarrays and differentially expressed miRNAs were validated using RT‑qPCR with 30 BPH and 5 healthy control samples. A total of 8 miRNAs, including miRNA (miR)‑96‑5p, miR‑1271‑5p, miR‑21‑3p, miR‑96‑5p, miR‑181a‑5p, miR‑143‑3p, miR‑4428 and miR‑106a‑5p were upregulated and 8 miRNAs (miR‑16‑5p, miR‑19b‑5p, miR‑940, miR‑25, miR‑486‑3p, miR‑30a‑3p, let‑7c and miR‑191) were downregulated. Additionally, miR‑96‑5p was demonstrated to have an inhibitory effect on the mRNA expression levels of the following genes: Mechanistic target of rapamycin (MTOR), RPTOR independent companion of MTOR complex 2, syntaxin 10, autophagy‑related protein 9A, zinc finger E‑box binding homeobox 1, caspase 2 and protein kinase c ε. Additionally, 16 differentially expressed miRNAs were identified using RT‑qPCR analysis. This preliminary study provides a solid basis for a further functional study to investigate the underlying regulatory mechanisms of BPH.
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1 

Cindolo L, Alvarez-Maestro M, Castellucci R and Schips L: Efficacy and safety of dutasteride for the treatment of symptomatic benign prostatic hyperplasia (BPH): A systematic review and meta-analysis. World J Urol. 33:441–442. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Kaplan SA: Re: Influence of immune inflammation on androgen receptor expression in benign prostatic hyperplasia tissue. J Urol. 189:10022013. View Article : Google Scholar : PubMed/NCBI

3 

Gacci M, Salvi M, Sebastianelli A, Vignozzi L, Corona G, McVary KT, Kaplan SA, Maggi M, Carini M and Oelke M: The use of a single daily dose of tadalafil to treat signs and symptoms of benign prostatic hyperplasia and erectile dysfunction. Res Rep Urol. 5:99–111. 2013.PubMed/NCBI

4 

Gao YA, Huang Y, Zhang R, Yang YD, Zhang Q, Hou M and Wang Y: Benign prostatic hyperplasia: Prostatic arterial embolization versus transurethral resection of the prostate-a prospective, randomized and controlled clinical trial. Radiology. 270:920–928. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Cochetti G, Poli G, Guelfi G, Boni A, Egidi MG and Mearini E: Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia: Evaluation of potential diagnostic and prognostic role. Onco Targets Ther. 9:7545–7553. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Tang B, Li N, Gu J, Zhuang Y, Li Q, Wang HG, Fang Y, Yu B, Zhang JY, Xie QH, et al: Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori. Autophagy. 8:1045–1057. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Andersen GB, Knudsen A, Hager H, Hansen LL and Tost J: miRNA profiling identifies deregulated miRNAs associated with osteosarcoma development and time to metastasis in two large cohorts. Mol Oncol. Nov 9–2017.(Epub ahead of print).

8 

Elliott KJ, Bourne AM, Takayanagi T, Takaguri A, Kobayashi T, Eguchi K and Eguchi S: ADAM17 silencing by adenovirus encoding miRNA-embedded siRNA revealed essential signal transduction by angiotensin II in vascular smooth muscle cells. J Mol Cell Cardiol. 62:1–7. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Bordinhao AL, Evangelista AF, Oliveira RJ, Macedo T, Silveira HC, Reis RM and Marques MM: MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. Oncol Rep. 36:3197–3206. 2016. View Article : Google Scholar : PubMed/NCBI

10 

Chen P, Zhao H, Huang J, Yan X, Zhang Y and Gao Y: MicroRNA-17-5p promotes gastric cancer proliferation, migration and invasion by directly targeting early growth response 2. Am J Cancer Res. 6:2010–2020. 2016.PubMed/NCBI

11 

Fu Y and Cao F: MicroRNA-125a-5p regulates cancer cell proliferation and migration through NAIF1 in prostate carcinoma. Onco Targets Ther. 8:3827–3835. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Chen WY, Liu SY, Chang YS, Yin JJ, Yeh HL, Mouhieddine TH, Hadadeh O, Abou-Kheir W and Liu YN: MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer. Oncotarget. 6:441–457. 2015.PubMed/NCBI

13 

Katz B, Reis ST, Viana NI, Morais DR, Moura CM, Dip N, Silva IA, Iscaife A, Srougi M and Leite KR: Comprehensive study of gene and microRNA expression related to epithelial-mesenchymal transition in prostate cancer. PLoS One. 9:e1137002014. View Article : Google Scholar : PubMed/NCBI

14 

Viana NI, Reis ST, Dip NG, Morais DR, Moura CM, Silva IA, Katz B, Srougi M, Leite KR and Antunes AA: MicroRNAs 143 and 145 may be involved in benign prostatic hyperplasia pathogenesis through regulation of target genes and proteins. Int J Biol Markers. 29:e246–252. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Haj-Ahmad TA, Abdalla MA and Haj-Ahmad Y: Potential urinary miRNA biomarker candidates for the accurate detection of prostate cancer among benign prostatic hyperplasia patients. J Cancer. 5:182–191. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Zhang N, Ji N, Jiang WM, Li ZY, Wang M, Wen JM, Li Y, Chen X and Chen JM: Hypoxia-induced autophagy promotes human prostate stromal cells survival and ER-stress. Biochem Biophys Res Commun. 464:1107–1112. 2015. View Article : Google Scholar : PubMed/NCBI

17 

Wu D and Gantier MP: Normalization of Affymetrix miRNA microarrays for the analysis of cancer samples. Methods Mol Biol. 1375:1–10. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Feber A, Xi L, Pennathur A, Gooding WE, Bandla S, Wu M, Luketich JD, Godfrey TE and Litle VR: MicroRNA prognostic signature for nodal metastases and survival in esophageal adenocarcinoma. Ann Thorac Surg. 91:1523–1530. 2011. View Article : Google Scholar : PubMed/NCBI

19 

Smeets A, Daemen A, Vanden Bempt I, Gevaert O, Claes B, Wildiers H, Drijkoningen R, Van Hummelen P, Lambrechts D, De Moor B, et al: Prediction of lymph node involvement in breast cancer from primary tumor tissue using gene expression profiling and miRNAs. Breast Cancer Res Treat. 129:767–776. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

21 

Gao F, Nan F, Feng J, Lv J, Liu Q and Xie S: Identification and characterization of microRNAs in Eucheuma denticulatum by high-throughput sequencing and bioinformatics analysis. RNA Biol. 13:343–352. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA and Surani MA: MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS One. 3:e17382008. View Article : Google Scholar : PubMed/NCBI

23 

Zhang C: MicroRNomics: A newly emerging approach for disease biology. Physiol Genomics. 33:139–147. 2008. View Article : Google Scholar : PubMed/NCBI

24 

Su J, Liang H, Yao W, Wang N, Zhang S, Yan X, Feng H, Pang W, Wang Y, Wang X, et al: MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. PLoS One. 9:e1144202014. View Article : Google Scholar : PubMed/NCBI

25 

Xu YF, Li YQ, Guo R, He QM, Ren XY, Tang XR, Jia WH, Kang TB, Zeng MS, Sun Y, et al: Identification of miR-143 as a tumour suppressor in nasopharyngeal carcinoma based on microRNA expression profiling. Int J Biochem Cell Biol. 61:120–128. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Zhang GJ, Li JS, Zhou H, Xiao HX, Li Y and Zhou T: MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1. J Exp Clin Cancer Res. 34:732015. View Article : Google Scholar : PubMed/NCBI

27 

Huang P, Ye B, Yang Y, Shi J and Zhao H: MicroRNA-181 functions as a tumor suppressor in non-small cell lung cancer (NSCLC) by targeting Bcl-2. Tumour Biol. 36:3381–3387. 2015. View Article : Google Scholar : PubMed/NCBI

28 

Khan K, Cunningham D, Peckitt C, Barton S, Tait D, Hawkins M, Watkins D, Starling N, Rao S, Begum R, et al: miR-21 expression and clinical outcome in locally advanced pancreatic cancer: Exploratory analysis of the pancreatic cancer Erbitux, radiotherapy and UFT (PERU) trial. Oncotarget. 7:12672–12681. 2016. View Article : Google Scholar : PubMed/NCBI

29 

Cheng CW, Wang HW, Chang CW, Chu HW, Chen CY, Yu JC, Chao JI, Liu HF, Ding SL and Shen CY: MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat. 134:1081–1093. 2012. View Article : Google Scholar : PubMed/NCBI

30 

Haflidadottir BS, Larne O, Martin M, Persson M, Edsjö A, Bjartell A and Ceder Y: Upregulation of miR-96 enhances cellular proliferation of prostate cancer cells through FOXO1. PLoS One. 8:e724002013. View Article : Google Scholar : PubMed/NCBI

31 

Ress AL, Stiegelbauer V, Winter E, Schwarzenbacher D, Kiesslich T, Lax S, Jahn S, Deutsch A, Bauernhofer T, Ling H, et al: MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients. Mol Carcinog. 54:1442–1450. 2015. View Article : Google Scholar : PubMed/NCBI

32 

Fendler A, Jung M, Stephan C, Erbersdobler A, Jung K and Yousef GM: The antiapoptotic function of miR-96 in prostate cancer by inhibition of FOXO1. PLoS One. 8:e808072013. View Article : Google Scholar : PubMed/NCBI

33 

Assal RA, El Tayebi HM, Hosny KA, Esmat G and Abdelaziz AI: A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and miR-182-5p on insulin-like growth factor II, insulin-like growth factor-1 receptor and insulin-like growth factor-binding protein-3 in hepatocellular carcinoma. Mol Med Rep. 12:645–650. 2015. View Article : Google Scholar : PubMed/NCBI

34 

Vishwamitra D, Li Y, Wilson D, Manshouri R, Curry CV, Shi B, Tang XM, Sheehan AM, Wistuba II, Shi P and Amin HM: MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression. Am J Pathol. 180:1772–1780. 2012. View Article : Google Scholar : PubMed/NCBI

35 

Wu Z, Liu K, Wang Y, Xu Z, Meng J and Gu S: Upregulation of microRNA-96 and its oncogenic functions by targeting CDKN1A in bladder cancer. Cancer Cell Int. 15:1072015. View Article : Google Scholar : PubMed/NCBI

36 

Yu S, Lu Z, Liu C, Meng Y, Ma Y, Zhao W, Liu J, Yu J and Chen J: miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer. Cancer Res. 70:6015–6025. 2010. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang N, Li Z, Bai F, Ji N, Zheng Y, Li Y, Chen J and Mao X: MicroRNA expression profiles in benign prostatic hyperplasia. Mol Med Rep 17: 3853-3858, 2018.
APA
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y. ... Mao, X. (2018). MicroRNA expression profiles in benign prostatic hyperplasia. Molecular Medicine Reports, 17, 3853-3858. https://doi.org/10.3892/mmr.2017.8318
MLA
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y., Chen, J., Mao, X."MicroRNA expression profiles in benign prostatic hyperplasia". Molecular Medicine Reports 17.3 (2018): 3853-3858.
Chicago
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y., Chen, J., Mao, X."MicroRNA expression profiles in benign prostatic hyperplasia". Molecular Medicine Reports 17, no. 3 (2018): 3853-3858. https://doi.org/10.3892/mmr.2017.8318
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang N, Li Z, Bai F, Ji N, Zheng Y, Li Y, Chen J and Mao X: MicroRNA expression profiles in benign prostatic hyperplasia. Mol Med Rep 17: 3853-3858, 2018.
APA
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y. ... Mao, X. (2018). MicroRNA expression profiles in benign prostatic hyperplasia. Molecular Medicine Reports, 17, 3853-3858. https://doi.org/10.3892/mmr.2017.8318
MLA
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y., Chen, J., Mao, X."MicroRNA expression profiles in benign prostatic hyperplasia". Molecular Medicine Reports 17.3 (2018): 3853-3858.
Chicago
Zhang, N., Li, Z., Bai, F., Ji, N., Zheng, Y., Li, Y., Chen, J., Mao, X."MicroRNA expression profiles in benign prostatic hyperplasia". Molecular Medicine Reports 17, no. 3 (2018): 3853-3858. https://doi.org/10.3892/mmr.2017.8318
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