|
1
|
Sullivan PF, Kendler KS and Neale MC:
Schizophrenia as a complex trait: Evidence from a meta-analysis of
twin studies. Arch General Psychia. 60:1187–1192. 2003. View Article : Google Scholar
|
|
2
|
Gejman PV, Sanders AR and Duan J: The role
of genetics in the etiology of schizophrenia. Psychiatr. Clin North
Am. 33:35–66. 2010. View Article : Google Scholar
|
|
3
|
Tarsy D, Lungu C and Baldessarini RJ:
Epidemiology of tardive dyskinesia before and during the era of
modern antipsychotic drugs. J Handb Clin Neurol. 100:601–616. 2011.
View Article : Google Scholar
|
|
4
|
Correll CU, Kane JM and Citrome LL:
Epidemiology, prevention, and assessment of tardive dyskinesia and
advances in treatment. J Clin Psychiatry. 78:1136–1147. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Csoka AB and Szyf M: Epigenetic
side-effects of common pharmaceuticals: A potential new field in
medicine and pharmacology. Med Hypotheses. 73:770–780. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lee HJ and Kang SG: Genetics of tardive
dyskinesia. Int Rev Neurobiol. 98:231–264. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lanning RK, Zai CC and Müller DJ:
Pharmacogenetics of tardive dyskinesia: An updated review of the
literature. Pharmacogenomics. 17:1339–1351. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Nishioka M, Bundo M, Kasai K and Iwamoto
K: DNA methylation in schizophrenia: Progress and challenges of
epigenetic studies. Genome Med. 4:962012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wockner LF, Noble EP, Lawford BR, Young
RM, Morris CP, Whitehall VL and Voisey J: Genome-wide DNA
methylation analysis of human brain tissue from schizophrenia
patients. Transl Psychiatry. 4:e3392014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Hannon E, Dempster E, Viana J, Burrage J,
Smith AR, Macdonald R, St Clair D, Mustard C, Breen G, Therman S,
et al: An integrated genetic-epigenetic analysis of schizophrenia:
Evidence for co-localization of genetic associations and
differential DNA methylation. Genome Biol. 17:1762016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lee SA and Huang KC: Epigenetic profiling
of human brain differential DNA methylation networks in
schizophrenia. BMC Med Genomics. 9 (Suppl 3):S682016. View Article : Google Scholar
|
|
12
|
Pries LK, Gülöksüz S and Kenis G: DNA
Methylation in Schizophrenia. Adv Exp Med Biol. 978:211–236. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhang P, Li YL, An HM and Tan YL:
Preliminary construction of DNA methylation profiles of
schizophrenia patients with tardive dyskinesia. Chin J Psychiatry.
51:13–19. 2018.
|
|
14
|
Li Y, Wang KS, Zhang P, Huang J, An H,
Wang N, Yang F, Wang Z, Tan S, Chen S and Tan YL: Quantitative DNA
methylation analysis of DLGAP2 gene using pyrosequencing in
schizophrenia with tardive dyskinesia: A linear mixed model
approach. Sci Rep. 8:174662018. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Abe H, Yamada N, Kamata K, Kuwaki T,
Shimada M, Osuga J, Shionoiri F, Yahagi N, Kadowaki T, Tamemoto H,
et al: Hypertension, hypertriglyceridemia, and impaired
endothelium-dependent vascular relaxation in mice lacking insulin
receptor substrate-1. J Clin Invest. 101:1784–1788. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Sun XJ, Rothenberg P, Kahn CR, Backer JM,
Araki E, Wilden PA, Cahill DA, Goldstein BJ and White MF: Structure
of the insulin receptor substrate IRS-1 defines a unique signal
transduction protein. Nature. 352:73–77. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Stoffel M, Espinosa R III, Keller SR,
Lienhard GE, Le Beau MM and Bell GI: Human insulin receptor
substrate-1 gene (IRS1): Chromosomal localization to 2q35-q36.1 and
identification of a simple tandem repeat DNA polymorphism.
Diabetologia. 36:335–337. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Nishiyama M, Inazawa J, Ariyama T,
Nakamura Y, Matsufuji S, Furusaka A, Tanaka T, Hayashi S and Wands
JR: The human insulin receptor substrate-1 gene (IRS1) is localized
on 2q36. Genomics. 20:139–141. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Myers MG Jr, Sun XJ and White MF: The
IRS-1 signaling system. Trends Biochem Sci. 19:289–293. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kulkarni RN, Winnay JN, Daniels M, Brüning
JC, Flier SN, Hanahan D and Kahn CR: Altered function of insulin
receptor substrate-1-deficient mouse islets and cultured beta-cell
lines. J Clin Invest. 104:R69–R75. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kido Y, Burks DJ, Withers D, Bruning JC,
Kahn CR, White MF and Accili D: Tissue-specific insulin resistance
in mice with mutations in the insulin receptor, IRS-1, and IRS-2. J
Clin Invest. 105:199–205. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kim JK, Fillmore JJ, Sunshine MJ, Albrecht
B, Higashimori T, Kim DW, Liu ZX, Soos TJ, Cline GW, O'Brien WR, et
al: PKC-theta knockout mice are protected from fat-induced insulin
resistance. J Clin Invest. 114:823–827. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Rung J, Cauchi S, Albrechtsen A, Shen L,
Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A,
Borch-Johnsen K, et al: Genetic variant near IRS1 is associated
with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat
Genet. 41:1110–1115. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rönn T, Volkov P, Gillberg L, Kokosar M,
Perfilyev A, Jacobsen AL, Jørgensen SW, Brøns C, Jansson PA,
Eriksson KF, et al: Impact of age, BMI and HbA1c levels on the
genome-wide DNA methylation and mRNA expression patterns in human
adipose tissue and identification of epigenetic biomarkers in
blood. Hum Mol Genet. 24:3792–3813. 2015.PubMed/NCBI
|
|
25
|
Fradin D, Boëlle PY, Belot MP, Lachaux F,
Tost J, Besse C, Deleuze JF, De Filippo G and Bougnères P:
Genome-wide methylation analysis identifies specific epigenetic
marks in severely obese children. Sci Rep. 7:463112017. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ma J, Cheng J, Wang L, Wang H, Xu L, Liu
P, Bu S, Zhang L, Le Y, Ye M, et al: No association between IRS-1
promoter methylation and type 2 diabetes. Mol Med Rep. 8:949–953.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Gunnell D, Lewis S, Wilkinson J, Georgieva
L, Davey GS, Day IN, Holly JM, O'Donovan MC, Owen MJ, Kirov G and
Zammit S: IGF1, growth pathway polymorphisms and schizophrenia: A
pooling study. Am J Med Genet B Neuropsychiatr Genet. 144B:117–120.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Montano C, Taub MA, Jaffe A, Briem E,
Feinberg JI, Trygvadottir R, Idrizi A, Runarsson A, Berndsen B, Gur
RC, et al: Association of DNA methylation differences with
schizophrenia in an epigenome-wide association study. JAMA
Psychiatry. 73:506–514. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Tost J and Gut IG: DNA methylation
analysis by pyrosequencing. Nat Protoc. 2:2265–2275. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mikeska T, Felsberg J, Hewitt CA and
Dobrovic A: Analysing DNA methylation using bisulphite
pyrosequencing. Methods Mol Biol. 791:33–35. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fakruddin M and Chowdhury A:
Pyrosequencing-An alternative to traditional Sanger sequencing. Am
J Biochem Biotech. 8:14–20. 2012. View Article : Google Scholar
|
|
32
|
Dayeh TA, Olsson AH, Volkov P, Almgren P,
Rönn T and Ling C: Identification of CpG-SNPs associated with type
2 diabetes and differential DNA methylation in human pancreatic
islets. Diabetologia. 56:1036–1046. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
American Psychiatric Association.
Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
Washington, DC: American Psychiatric Association; 1994
|
|
34
|
Schooler NR and Kane JM: Research
diagnoses for tardive dyskinesia. Arch Gen Psychiatry. 39:486–487.
1982. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Fan B: Abnormal involuntary movement
rating scale (AIMS). Shanghai Arch Psychiat. 80–81. 1984.
|
|
36
|
Kay SR, Fiszbein A and Opler LA: The
positive and negative syndrome scale (PANSS) for schizophrenia.
Schizophr Bull. 13:261–276. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
White MF: Insulin signaling in health and
disease. Science. 302:1710–1711. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Burks DJ and White MF: IRS proteins and
β-cell function. Diabetes. 50:140–145. 2001. View Article : Google Scholar
|
|
39
|
Withers DJ, Burks DJ, Towery HH, Altamuro
SL, Flint CL and White MF: IRS-2 coordinates IGF-1
receptor-mediated beta-cell development and peripheral insulin
signalling. Nat Genet. 23:32–40. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
40
|
Lautier C, El Mkadem SA, Renard E, Brun
JF, Gris JC, Bringer J and Grigorescu F: Complex haplotypes of
IRS2 gene are associated with severe obesity and reveal
heterogeneity in the effect of Gly1057Asp mutation. Hum Genet.
113:34–43. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Slattery ML, Samowitz W, Curtin K, Ma KN,
Hoffman M, Caan B and Neuhausen S: Associations among IRS1, IRS2,
IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.
Cancer Epidemiol Biomark Prev. 13:1206–1214. 2004.
|
|
42
|
Neuhausen SL, Brummel S, Ding YC, Singer
CF, Pfeiler G, Lynch HT, Nathanson KL, Rebbeck TR, Garber JE, Couch
F, et al: Genetic variation in insulin-like growth factor signaling
genes and breast cancer risk among BRCA1 and BRCA2 carriers. Breast
Cancer Res. 11:R762009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Feng X, Tucker KL, Parnell LD, Shen J, Lee
YC, Ordovas JM, Ling WH and Lai CQ: Insulin receptor substrate 1
(IRS1) variants confer risk of diabetes in the Boston Puerto Rican
Health Study. Asia Pac J Clin Nutr. 22:150–159. 2013.PubMed/NCBI
|
|
44
|
Winder T, Giamas G, Wilson PM, Zhang W,
Yang D, Bohanes P, Ning Y, Gerger A, Stebbing J and Lenz HJ:
Insulin-like growth factor receptor polymorphism defines clinical
outcome in estrogen receptor-positive breast cancer patients
treated with tamoxifen. Pharmacogen J. 14:28–34. 2014. View Article : Google Scholar
|
|
45
|
Jones JI and Clemmons DR: Insulin-like
growth factors and their binding proteins: Biological actions.
Endocr Rev. 16:3–34. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Laban C, Bustin SA and Jenkins PJ: The
GH-IGF-I axis and breast cancer. Trends Endocrinol Metab. 14:28–34.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Che F, Fu Q, Li X, Gao N, Qi F, Sun Z, Du
Y and Li M: Association of insulin receptor H1085H C>T, insulin
receptor substrate 1 G972R and insulin receptor substrate 2 1057G/A
polymorphisms with refractory temporal lobe epilepsy in Han
Chinese. Seizure. 25:178–180. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Park HJ, Kim SK, Kang WS, Park JK, Kim YJ,
Nam M, Kim JW and Chung JH: Association between IRS1 gene
polymorphism and autism spectrum disorder: A pilot case-control
study in Korean males. Int J Mol Sci. 17:E12272016. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Suvisaari J, Perälä J, Saarni SI, Härkänen
T, Pirkola S, Joukamaa M, Koskinen S, Lönnqvist J and Reunanen A:
Type 2 diabetes among persons with schizophrenia and other
psychotic disorders in a general population survey. Eur Arch
Psychiatry Clin Neurosci. 258:129–136. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Irvin MR, Wiener HW, Perry RP, Savage RM
and Go RC: Genetic risk factors for type 2 diabetes with
pharmacologic intervention in African-American patients with
schizophrenia or schizoaffective disorder. Schizophr Res.
114:50–56. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Bellivier F: Schizophrenia, antipsychotics
and diabetes: Genetic aspects. Eur Psychiatry. 20 (Suppl
4):S335–S339. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Lin PI and Shuldiner AR: Rethinking the
genetic basis for comorbidity of schizophreniaand type 2 diabetes.
Schizophr Res. 123:234–243. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Hansen T, Ingason A, Djurovic S, Melle I,
Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S,
Rietschel M, et al: At-risk variant in TCF7L2 for type II diabetes
increases risk of schizophrenia. Biol Psychiatry. 70:59–63. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Zhang X, Hui L, Liu Y, Wang ZQ, You Y,
Miao LN, Sun SL, Guan SL, Xiang Y, Kosten TR and Zhang XY: The type
2 diabetes mellitus susceptibility gene IGF2BP2 is associated with
schizophrenia in a Han Chinese population. J Clin Psychiatry.
74:e287–e292. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Liu Y, Li Z, Zhang M, Deng Y, Yi Z and Shi
T: Exploring the pathogenetic association between schizophreniaand
type 2 diabetes mellitus diseases based on pathway analysis. BMC
Med Genomics. 6 (Suppl 1):S172013. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Talbot K, Wang HY, Kazi H, Han LY, Bakshi
KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, et
al: Demonstrated brain insulin resistance in Alzheimer's disease
patients is associated with IGF-1 resistance, IRS-1 dysregulation,
and cognitive decline. J Clin Invest. 122:1316–1338. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Yarchoan M, Toledo JB, Lee EB, Arvanitakis
Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ and
Arnold SE: Abnormal serine phosphorylation of insulin receptor
substrate 1 is associated with tau pathology in Alzheimer's disease
and tauopathies. Acta Neuropathol. 128:679–689. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Kapogiannis D, Boxer A, Schwartz JB, Abner
EL, Biragyn A, Masharani U, Frassetto L, Petersen RC, Miller BL and
Goetzl EJ: Dysfunctionally phosphorylated type 1 insulin receptor
substrate in neural-derived blood exosomes of preclinical
Alzheimer's disease. FASEB J. 29:589–596. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Tanokashira D, Fukuokaya W and Taguchi A:
Involvement of insulin receptor substrates in cognitive impairment
and Alzheimer's disease. Neural Regen Res. 14:1330–1334. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Douaud G, Groves AR, Tamnes CK, Westlye
LT, Duff EP, Engvig A, Walhovd KB, James A, Gass A, Monsch AU, et
al: A common brain network links development, aging, and
vulnerability to disease. Proc Natl Acad Sci USA. 111:17648–17653.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Schrijvers EM, Witteman JC, Sijbrands EJ,
Hofman A, Koudstaal PJ and Breteler MM: Insulin metabolism and the
risk of Alzheimer disease: The Rotterdam Study. Neurology.
75:1982–1987. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Qiu C, Sigurdsson S, Zhang Q, Jonsdottir
MK, Kjartansson O, Eiriksdottir G, Garcia ME, Harris TB, van Buchem
MA, et al: Diabetes, markers of brain pathology and cognitive
function: The Age, Gene/Environment Susceptibility-Reykjavik Study.
Ann Neurol. 75:138–146. 2014. View Article : Google Scholar : PubMed/NCBI
|
