[Corrigendum] Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α
Affiliations: Institute of TBI and Neuroscience of Chinese People's Armed Police Force, Tianjin Key Laboratory of Neurotrauma Repair, Center for Neurology and Neurosurgery of Affiliated Hospital of Logistics University of PAP, Tianjin 300162, P.R. China, Central Laboratory of Logistics University of PAP, Tianjin 300309, P.R. China, Tianjin Key Laboratory for Biomarkers of Occupational and Environmental Hazard, Logistics University of PAP, Tianjin 300309, P.R. China
- Published online on: January 11, 2021 https://doi.org/10.3892/mmr.2021.11836
- Article Number: 197
Copyright : © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
This article is mentioned in:
Mol Med Rep 17: [Related article:] 5595-5600, 2018; DOI: 10.3892/mmr.2018.8587
Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that several pairings of panels in Fig. 5, as shown on p. 5599, were strikingly similar. After having examined their original data, the authors realized that they uploaded some images incorrectly during the process of compiling this figure, and that there were duplicated data panels in this figure. However, the authors were able to consult their original data, and had access to the correct images.
High content screening analyses of the changes in protein levels treated with ouabain. U-87MG cells were treated with the different concentrations of ouabain for 24 h and fluorescence images were captured. Scale bar=50 µm. mTOR, mammalian target of rapamycin; p-, phosphorylated; HIF-1α, hypoxia inducible factor-1α.
The revised version of Fig. 5, showing the correct data for the Akt/Control, p-Akt/Control, mTOR/0.05 μM Ouabain, HIF-1α/0.05 μM Ouabain and Akt/0.5 μM Ouabain experiments, is shown opposite. Note that the replacement of the erroneous data does not affect either the results or the conclusions reported in this paper, and all the authors agree to this Corrigendum. The authors are grateful to the Editor of Molecular Medicine Reports for granting them this opportunity to publish a Corrigendum, and apologize to the readership for any inconvenience caused.