Journal Articles

Article Open Access

IL-32 exacerbates adenoid hypertrophy via activating NLRP3-mediated cell pyroptosis, which promotes inflammation

Junmei Zhang, Xuyuan Sun, Lingling Zhong, Bei Shen

Article Number: 226 Published online on: 24 January 2021
Review

Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy (Review)

Linfeng Luo, Guoheng Mo, Deqiang Huang

Article Number: 225 Published online on: 24 January 2021
Article Open Access

Coniferaldehyde prevents articular cartilage destruction in a murine model via Nrf2/HO‑1 pathway

Dawei Cai, Jieling Wang, Sichun Chen, Longhai Jiang, Jinwei Chen, Ji Wu, Jian Qin

Article Number: 224 Published online on: 24 January 2021
Article Open Access

Simiaosan alleviates the symptoms of gouty arthritis via the NALP3/IL‑1β pathway

Xianzhen Zhang, Huideng Ding, Gang Hu, Ying Lu

Article Number: 223 Published online on: 24 January 2021
Article Open Access

H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes

Jiezhi Lin, Jinyu Wei, Yanling Lv, Xingyue Zhang, Ruo Fan Yi, Chen Dai, Qiong Zhang, Jiezhi Jia, Dongxia Zhang, Yuesheng Huang

Article Number: 222 Published online on: 21 January 2021
Article

Nrf2‑Keap1‑ARE‑NQO1 signaling attenuates hyperoxia‑induced lung cell injury by inhibiting apoptosis

Bowen Weng, Xiaoyue Zhang, Xiaoyun Chu, Xiaohui Gong, Cheng Cai

Article Number: 221 Published online on: 21 January 2021
Article

Effect of Notch1 on neural tube defects and neural stem cell differentiation induced by all‑trans retinoic acid

Na Chen, Jiaming Xu, Xinying Zhang, Shuwei Li, Weiwei Zhu, Haibin Cui, Yu Sun, Bo Han, Aihua Ma

Article Number: 220 Published online on: 21 January 2021
Article Open Access

Shengxian decoction decreases doxorubicin‑induced cardiac apoptosis by regulating the TREM1/NF‑κB signaling pathway

Lei Yao, Mingtai Gui, Jianhua Li, Bo Lu, Jing Wang, Xunjie Zhou, Deyu Fu

Article Number: 219 Published online on: 20 January 2021
Article Open Access

Long non‑coding RNA NEAT1 promotes pulmonary fibrosis by regulating the microRNA‑455‑3p/SMAD3 axis

Yuan Liu, Fu-Ai Lu, Le Wang, Yong-Fu Wang, Chun-Feng Wu

Article Number: 218 Published online on: 20 January 2021
Article Open Access

β‑Lapachone ameliorates L‑DOPA‑induced dyskinesia in a 6‑OHDA‑induced mouse model of Parkinson's disease

Young-Kyoung Ryu, Hye-Yeon Park, Jun Go, In-Bok Lee, Young-Keun Choi, Chul-Ho Lee, Kyoung-Shim Kim

Article Number: 217 Published online on: 20 January 2021
Article

Potassium bromate-induced cell model of age-related macular degeneration in vitro

Shu-Chun Kuo, Yingxiao Li, Kai-Chun Cheng, Chia-Chen Hsu, Juei-Tang Cheng, Hui-Hsuan Lau

Article Number: 216 Published online on: 20 January 2021
Article Open Access

Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF‑κB signalling pathway in diabetic cardiomyopathy rats

Qinyang Jin, Qin Zhu, Kai Wang, Mengli Chen, Xinli Li

Article Number: 215 Published online on: 20 January 2021
Article Open Access

Recombinant high‑mobility group box 1 induces cardiomyocyte hypertrophy by regulating the 14‑3‑3η, PI3K and nuclear factor of activated T cells signaling pathways

Feifei Su, Miaoqian Shi, Jian Zhang, Yan Li, Jianwei Tian

Article Number: 214 Published online on: 20 January 2021
Article Open Access

miR-140-5p regulates vascular smooth muscle cell viability, migration and apoptosis by targeting ROBO4 gene expression in atherosclerosis

Yi Luo, Yangmin Li, Hong Peng, Yu Zhao

Article Number: 213 Published online on: 19 January 2021
Article Open Access

Long non‑coding RNA PITPNA‑AS1 silencing suppresses proliferation, metastasis and epithelial‑mesenchymal transition in non‑small cell lung cancer cells by targeting microRNA‑32‑5p Corrigendum in /10.3892/mmr.2021.11911

Gang Chen, Zhifeng Zheng, Junsheng Li, Peigang Zhang, Zhenjun Wang, Shiping Guo, Jun Ma, Jian Shen, Huixin Li

Article Number: 212 Published online on: 18 January 2021
Article Open Access

lncRNA LINC00963 downregulation regulates colorectal cancer tumorigenesis and progression via the miR‑10b/FGF13 axis

Yujin Wu, Longling Cong, Wenjian Chen, Xuechuan Wang, Fanghua Qiu

Article Number: 211 Published online on: 18 January 2021
Article Open Access

Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model

Katsuyuki Tokinoya, Nanami Sekine, Kai Aoki, Seiko Ono, Tomoaki Kuji, Takehito Sugasawa, Yasuko Yoshida, Kazuhiro Takekoshi

Article Number: 210 Published online on: 18 January 2021
Article

1,7‑Bis(4‑hydroxy‑3‑methoxyphenyl)‑1,4,6‑heptatrien‑3‑one alleviates lipopolysaccharide‑induced inflammation by targeting NF‑κB translocation in murine macrophages and it interacts with MD2 in silico

Chutima Jansakun, Wanatsanan Chulrik, Waraluck Chaichompoo, Pathumwadee Yotmanee, Kanokporn Lehboon, Wilanee Chunglok, Apsorn Sattayakhom, Poonsit Hiransai, Kornyok Kamdee, Tanyarath Utaipan, Apichart Suksamrarn, Warangkana Chunglok

Article Number: 209 Published online on: 18 January 2021
Article Open Access

Cytotoxic effect of CLL‑1 CAR‑T cell immunotherapy with PD‑1 silencing on relapsed/refractory acute myeloid leukemia

Guoqiang Lin, Yanming Zhang, Lei Yu, Depei Wu

Article Number: 208 Published online on: 18 January 2021
Article Open Access

P21‑activated kinase 1 mediates angiotensin II‑induced differentiation of human atrial fibroblasts via the JNK/c‑Jun pathway

Yafei Zhou, Ying Xie, Tao Li, Peng Zhang, Tangting Chen, Zhongcai Fan, Xiaoqiu Tan

Article Number: 207 Published online on: 18 January 2021
Article Open Access

Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells

Wenyi Fang, Peilin Zhao, Aling Shen, Liya Liu, Hongwei Chen, Youqin Chen, Jun Peng, Thomas J. Sferra, Senthilkumar Sankararaman, Yunfeng Luo, Xiao Ke

Article Number: 205 Published online on: 14 January 2021
Article Open Access

Knockdown of FAM225B inhibits the progression of the hypertrophic scar following glaucoma surgery by inhibiting autophagy

Xianpeng Ma, Lili Liu

Article Number: 204 Published online on: 14 January 2021
Article

Discovery of natural adenosine monophosphate‑activated protein kinase activators through virtual screening and activity verification studies

Jia Hao, Zhen Yang, Jian Li, Lifeng Han, Yi Zhang, Tao Wang

Article Number: 203 Published online on: 13 January 2021
Article Open Access

SCARA5 suppresses the proliferation and migration, and promotes the apoptosis of human retinoblastoma cells by inhibiting the PI3K/AKT pathway

Jinwei Wang, Sha Wang, Lu Chen, Jia Tan

Article Number: 202 Published online on: 13 January 2021
Article Open Access

N‑acetylcysteine inhibits atherosclerosis by correcting glutathione‑dependent methylglyoxal elimination and dicarbonyl/oxidative stress in the aorta of diabetic mice

Xin Fang, Lihua Liu, Shaoqiong Zhou, Mengen Zhu, Bin Wang

Article Number: 201 Published online on: 13 January 2021
Article Open Access

miR‑653‑5p suppresses the growth and migration of breast cancer cells by targeting MAPK6

Mei Zhang, Hongwei Wang, Xiaomei Zhang, Fengping Liu

Article Number: 200 Published online on: 12 January 2021
Article

miR‑583 inhibits the proliferation and invasion of prostate cancer cells by targeting JAK1

Zhongyi Li, Jianheng Chen

Article Number: 199 Published online on: 12 January 2021
Review Open Access

Role of Munc18-1 in the biological functions and pathogenesis of neurological disorders (Review)

Fajuan Tang, Dongqiong Xiao, Lin Chen, Hu Gao, Xihong Li

Article Number: 198 Published online on: 12 January 2021
Correction Open Access

[Corrigendum] Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α

Xiao-Sa Yang, Zhong-Wei Xu, Tai-Long Yi, Rui-Cheng Xu, Jie Li, Wen-Bin Zhang, Sai Zhang, Hong-Tao Sun, Ze-Qi Yu, Hao-Xiang Xu, Yue Tu, Shi-Xiang Cheng

Article Number: 197 Published online on: 11 January 2021
Article Open Access

Effect of long non‑coding RNA AK021443 on promoting hepatic fibrosis in vitro

Yuxin Yang, Zongsu Min

Article Number: 196 Published online on: 11 January 2021
Article Open Access

Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways

Yousong Li, Jinsheng Gao, Xi Yang, Tao Li, Baoxue Yang, Aixingzi Aili

Article Number: 195 Published online on: 11 January 2021
Article Open Access

MicroRNA‑153 attenuates hypoxia‑induced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3

Minjie Zhao, Wei Wang, Ya Lu, Nan Wang, Delei Kong, Lina Shan

Article Number: 194 Published online on: 07 January 2021
Article Open Access

Bioinformatics analysis identifies biomarkers associated with poor prognosis in diffuse‑type gastric cancer

Sheng Li, Chao Yu, Yuanguang Cheng, Fangchao Du, Gang Wen

Article Number: 193 Published online on: 07 January 2021
Article Open Access

Genistein alleviates chronic vascular inflammatory response via the miR‑21/NF‑κB p65 axis in lipopolysaccharide‑treated mice

Xiaolin Xie, Li Cong, Sujuan Liu, Liping Xiang, Xiaohua Fu

Article Number: 192 Published online on: 07 January 2021
Article Open Access

Long non‑coding RNA MEG3 inhibits cell migration and invasion of non‑small cell lung cancer cells by regulating the miR‑21‑5p/PTEN axis

Dongjin Lv, Qing Bi, Yunxia Li, Jie Deng, Na Wu, Shu Hao, Mingli Zhao

Article Number: 191 Published online on: 06 January 2021
Article Open Access

miR‑212 promotes renal interstitial fibrosis by inhibiting hypoxia‑inducible factor 1‑α inhibitor

Yun Zhang, Guo-Xin Zhang, Li-Shuang Che, Shu-Han Shi, Yue-Ting Li

Article Number: 189 Published online on: 06 January 2021
Article Open Access

Nogo‑66 promotes β‑amyloid protein secretion via NgR/ROCK‑dependent BACE1 activation

Qing-Qing Xie, Xiao Feng, Yi-Υun Huang, Nian Fang, Hua Yi, Zi-Jian Wang, Qiao-Υu Cao, Guo-Feng Lou, Jun-Ping Pan, Yang Hu, Fang-Cheng Li, Qing Zheng, Fei Xiao

Article Number: 188 Published online on: 05 January 2021
Article Open Access

Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal cancer cells via upregulation of the microRNA-34a/449a cluster

Guangyu Ji, Wenjuan Zhou, Xian Li, Jingyi Du, Xinyue Li, Hongbo Hao

Article Number: 187 Published online on: 05 January 2021
Article Open Access

Vascular endothelial ERp72 is involved in the inflammatory response in a rat model of skeletal muscle injury

Noureddine Ben Khalaf, Dalal Al‑Μehatab, Dahmani M. Fathallah

Article Number: 186 Published online on: 04 January 2021
Article Open Access

Comprehensive RNA expression profile of therapeutic adipose‑derived mesenchymal stem cells co‑cultured with degenerative nucleus pulposus cells

Zhihua Han, Qiugen Wang, Xiaoming Wu, Jiandong Wang, Liang Gao, Ruipeng Guo, Jianhong Wu

Article Number: 185 Published online on: 04 January 2021
Article

Elevation of hypertonicity‑induced protein NFAT5 promotes apoptosis of human umbilical vein endothelial cells through the NF‑κB pathway

Xupin Xie, Changpin Huang, Dong Xu, Yongchang Liu, Mengxiao Hu, Jianyun Long, Xin Fang

Article Number: 184 Published online on: 04 January 2021
Article Open Access

miR‑375 affects the hedgehog signaling pathway by downregulating RAC1 to inhibit hepatic stellate cell viability and epithelial‑mesenchymal transition

Zhiwei Liang, Jian Li, Longshuan Zhao, Yilei Deng

Article Number: 182 Published online on: 31 December 2020
Article Open Access

9‑Hydroxy‑isoegomaketone inhibits LPS‑induced NO and inflammatory cytokine production in RAW264.7 cells

Hyun Mi Kim, Bomi Nam, Sunil Babu Paudel, Joo-Won Nam, Ah-Reum Han, Hye Gwang Jeong, Chang Hyun Jin

Article Number: 181 Published online on: 31 December 2020
Article Open Access

Intestinal dysbacteriosis leads to kidney stone disease

Enyang Zhao, Wenfu Zhang, Bo Geng, Bosen You, Wanhui Wang, Xuedong Li

Article Number: 180 Published online on: 31 December 2020
Review Open Access

Research progress of the transcription factor Brn4 (Review)

Yuying Wu, Xunrui Zhang, Jue Wang, Guohua Jin, Xinhua Zhang

Article Number: 179 Published online on: 31 December 2020
Article
Article

circFOXO3 protects cardiomyocytes against radiation‑induced cardiotoxicity

Yiming Qiu, Xianping Xie, Luhua Lin

Article Number: 177 Published online on: 30 December 2020
Article Open Access
Article Open Access

Electroacupuncture effects on the P2X4R pathway in microglia regulating the excitability of neurons in the substantia gelatinosa region of rats with spinal nerve ligation

Yuyin Zheng, Chengqian Jia, Xia Jiang, Jie Chen, Xiao-Long  Chen, Xinwang Ying, Jiayu Wu, Mingchen Jiang, Guanhu Yang, Wenzhan Tu, Kecheng Zhou, Songhe Jiang

Article Number: 175 Published online on: 30 December 2020
Correction Open Access

[Corrigendum] Anticancer effect of quinacrine on diffuse large B‑cell lymphoma via inhibition of MSI2‑NUMB signaling pathway

Shujun Yang, Lixia Sheng, Kaihong Xu, Yi Wang, Huiling Zhu, Ping Zhang, Qitian Mu, Guifang Ouyang

Article Number: 174 Published online on: 29 December 2020
Article Open Access

Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells

Yoshiaki Tabuchi, Hideyuki Hasegawa, Nobuo Suzuki, Yukihiro Furusawa, Tetsushi  Hirano, Ryo Nagaoka, Jun Hirayama, Nobuhiko Hoshi, Takashi Mochizuki

Article Number: 173 Published online on: 23 December 2020
Article Open Access

MicroRNA‑149‑3p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma

Qin Shen, Hong Zhu, Qiaoling Lei, Luyuan Chen, Dajiang Yang, Wen Sui

Article Number: 172 Published online on: 23 December 2020
Article Open Access

Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression

Xiao-Hua Zhang, Hong-Yu Zhao, Yu Wang, Lin Di, Xin-Yu Liu, Feng Qian, Shu-Rong Liu

Article Number: 171 Published online on: 23 December 2020
Article

Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species

Yun Fu, Yuedian Ye, Guifang Zhu, Yangwei Xu, Jingbo Sun, Hongmei Wu, Feiyan Feng, Zhihui Wen, Shanshan Jiang, Yanyan Li, Qingling Zhang

Article Number: 170 Published online on: 23 December 2020
Article Open Access

Investigating the effect of lncRNA HOTAIR on apoptosis induced by myocardial ischemia-reperfusion injury

Jijing Fang, Weihong Zheng, Pengfei Hu, Jiale Wu

Article Number: 169 Published online on: 23 December 2020
Article Open Access

Silencing of long non‑coding RNA NEAT1 inhibits hepatocellular carcinoma progression by downregulating SMO by sponging microRNA‑503

Chuihua Sun, Ting Xiao, Ying Xiao, Yunbao Li

Article Number: 168 Published online on: 23 December 2020
Review Open Access

Role of Wnt5a in periodontal tissue development, maintenance, and periodontitis: Implications for periodontal regeneration (Review)

Xiuqun Wei, Qian Liu, Shujuan Guo, Yafei Wu

Article Number: 167 Published online on: 23 December 2020
Journal Cover

March-2021
Volume 23 Issue 3

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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