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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2021 Volume 23 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

IL-32 exacerbates adenoid hypertrophy via activating NLRP3-mediated cell pyroptosis, which promotes inflammation

Junmei Zhang, Xuyuan Sun, Lingling Zhong, Bei Shen
Article Number: 226
Published online on: 24 January 2021

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Review

Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy (Review)

Linfeng Luo, Guoheng Mo, Deqiang Huang
Article Number: 225
Published online on: 24 January 2021

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Coniferaldehyde prevents articular cartilage destruction in a murine model via Nrf2/HO‑1 pathway

Dawei Cai, Jieling Wang, Sichun Chen, Longhai Jiang, Jinwei Chen, Ji Wu, Jian Qin
Article Number: 224
Published online on: 24 January 2021

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Simiaosan alleviates the symptoms of gouty arthritis via the NALP3/IL‑1β pathway

Xianzhen Zhang, Huideng Ding, Gang Hu, Ying Lu
Article Number: 223
Published online on: 24 January 2021

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H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes

Jiezhi Lin, Jinyu Wei, Yanling Lv, Xingyue Zhang, Ruo Fan Yi, Chen Dai, Qiong Zhang, Jiezhi Jia, Dongxia Zhang, Yuesheng Huang
Article Number: 222
Published online on: 21 January 2021

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Article

Nrf2‑Keap1‑ARE‑NQO1 signaling attenuates hyperoxia‑induced lung cell injury by inhibiting apoptosis

Bowen Weng, Xiaoyue Zhang, Xiaoyun Chu, Xiaohui Gong, Cheng Cai
Article Number: 221
Published online on: 21 January 2021

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Article

Effect of Notch1 on neural tube defects and neural stem cell differentiation induced by all‑trans retinoic acid

Na Chen, Jiaming Xu, Xinying Zhang, Shuwei Li, Weiwei Zhu, Haibin Cui, Yu Sun, Bo Han, Aihua Ma
Article Number: 220
Published online on: 21 January 2021

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Article Open Access

Shengxian decoction decreases doxorubicin‑induced cardiac apoptosis by regulating the TREM1/NF‑κB signaling pathway Retraction in /10.3892/mmr.2024.13159

Lei Yao, Mingtai Gui, Jianhua Li, Bo Lu, Jing Wang, Xunjie Zhou, Deyu Fu
Article Number: 219
Published online on: 20 January 2021

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Article Open Access

Long non‑coding RNA NEAT1 promotes pulmonary fibrosis by regulating the microRNA‑455‑3p/SMAD3 axis

Yuan Liu, Fu-Ai Lu, Le Wang, Yong-Fu Wang, Chun-Feng Wu
Article Number: 218
Published online on: 20 January 2021

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β‑Lapachone ameliorates L‑DOPA‑induced dyskinesia in a 6‑OHDA‑induced mouse model of Parkinson's disease

Young-Kyoung Ryu, Hye-Yeon Park, Jun Go, In-Bok Lee, Young-Keun Choi, Chul-Ho Lee, Kyoung-Shim Kim
Article Number: 217
Published online on: 20 January 2021

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Article

Potassium bromate-induced cell model of age-related macular degeneration in vitro

Shu-Chun Kuo, Yingxiao Li, Kai-Chun Cheng, Chia-Chen Hsu, Juei-Tang Cheng, Hui-Hsuan Lau
Article Number: 216
Published online on: 20 January 2021

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Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF‑κB signalling pathway in diabetic cardiomyopathy rats

Qinyang Jin, Qin Zhu, Kai Wang, Mengli Chen, Xinli Li
Article Number: 215
Published online on: 20 January 2021

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Recombinant high‑mobility group box 1 induces cardiomyocyte hypertrophy by regulating the 14‑3‑3η, PI3K and nuclear factor of activated T cells signaling pathways

Feifei Su, Miaoqian Shi, Jian Zhang, Yan Li, Jianwei Tian
Article Number: 214
Published online on: 20 January 2021

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Article Open Access

miR-140-5p regulates vascular smooth muscle cell viability, migration and apoptosis by targeting ROBO4 gene expression in atherosclerosis

Yi Luo, Yangmin Li, Hong Peng, Yu Zhao
Article Number: 213
Published online on: 19 January 2021

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Long non‑coding RNA PITPNA‑AS1 silencing suppresses proliferation, metastasis and epithelial‑mesenchymal transition in non‑small cell lung cancer cells by targeting microRNA‑32‑5p Corrigendum in /10.3892/mmr.2021.11911

Gang Chen, Zhifeng Zheng, Junsheng Li, Peigang Zhang, Zhenjun Wang, Shiping Guo, Jun Ma, Jian Shen, Huixin Li
Article Number: 212
Published online on: 18 January 2021

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lncRNA LINC00963 downregulation regulates colorectal cancer tumorigenesis and progression via the miR‑10b/FGF13 axis

Yujin Wu, Longling Cong, Wenjian Chen, Xuechuan Wang, Fanghua Qiu
Article Number: 211
Published online on: 18 January 2021

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Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model

Katsuyuki Tokinoya, Nanami Sekine, Kai Aoki, Seiko Ono, Tomoaki Kuji, Takehito Sugasawa, Yasuko Yoshida, Kazuhiro Takekoshi
Article Number: 210
Published online on: 18 January 2021

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Article

1,7‑Bis(4‑hydroxy‑3‑methoxyphenyl)‑1,4,6‑heptatrien‑3‑one alleviates lipopolysaccharide‑induced inflammation by targeting NF‑κB translocation in murine macrophages and it interacts with MD2 in silico

Chutima Jansakun, Wanatsanan Chulrik, Waraluck Chaichompoo, Pathumwadee Yotmanee, Kanokporn Lehboon, Wilanee Chunglok, Apsorn Sattayakhom, Poonsit Hiransai, Kornyok Kamdee, Tanyarath Utaipan, Apichart Suksamrarn, Warangkana Chunglok
Article Number: 209
Published online on: 18 January 2021

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Cytotoxic effect of CLL‑1 CAR‑T cell immunotherapy with PD‑1 silencing on relapsed/refractory acute myeloid leukemia

Guoqiang Lin, Yanming Zhang, Lei Yu, Depei Wu
Article Number: 208
Published online on: 18 January 2021

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P21‑activated kinase 1 mediates angiotensin II‑induced differentiation of human atrial fibroblasts via the JNK/c‑Jun pathway

Yafei Zhou, Ying Xie, Tao Li, Peng Zhang, Tangting Chen, Zhongcai Fan, Xiaoqiu Tan
Article Number: 207
Published online on: 18 January 2021

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Gryllus bimaculatus extract protects against lipopolysaccharide and palmitate-induced production of proinflammatory cytokines and inflammasome formation

Woo-Jae Park, Jung-Soon Han
Article Number: 206
Published online on: 14 January 2021

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Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells

Wenyi Fang, Peilin Zhao, Aling Shen, Liya Liu, Hongwei Chen, Youqin Chen, Jun Peng, Thomas J. Sferra, Senthilkumar Sankararaman, Yunfeng Luo, Xiao Ke
Article Number: 205
Published online on: 14 January 2021

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Article Open Access

Knockdown of FAM225B inhibits the progression of the hypertrophic scar following glaucoma surgery by inhibiting autophagy

Xianpeng Ma, Lili Liu
Article Number: 204
Published online on: 14 January 2021

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Article

Discovery of natural adenosine monophosphate‑activated protein kinase activators through virtual screening and activity verification studies

Jia Hao, Zhen Yang, Jian Li, Lifeng Han, Yi Zhang, Tao Wang
Article Number: 203
Published online on: 13 January 2021

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Article Open Access

SCARA5 suppresses the proliferation and migration, and promotes the apoptosis of human retinoblastoma cells by inhibiting the PI3K/AKT pathway

Jinwei Wang, Sha Wang, Lu Chen, Jia Tan
Article Number: 202
Published online on: 13 January 2021

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Article Open Access

N‑acetylcysteine inhibits atherosclerosis by correcting glutathione‑dependent methylglyoxal elimination and dicarbonyl/oxidative stress in the aorta of diabetic mice

Xin Fang, Lihua Liu, Shaoqiong Zhou, Mengen Zhu, Bin Wang
Article Number: 201
Published online on: 13 January 2021

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Article Open Access

miR‑653‑5p suppresses the growth and migration of breast cancer cells by targeting MAPK6

Mei Zhang, Hongwei Wang, Xiaomei Zhang, Fengping Liu
Article Number: 200
Published online on: 12 January 2021

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Article

miR‑583 inhibits the proliferation and invasion of prostate cancer cells by targeting JAK1

Zhongyi Li, Jianheng Chen
Article Number: 199
Published online on: 12 January 2021

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Review Open Access

Role of Munc18-1 in the biological functions and pathogenesis of neurological disorders (Review)

Fajuan Tang, Dongqiong Xiao, Lin Chen, Hu Gao, Xihong Li
Article Number: 198
Published online on: 12 January 2021

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Correction Open Access

[Corrigendum] Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α

Xiao-Sa Yang, Zhong-Wei Xu, Tai-Long Yi, Rui-Cheng Xu, Jie Li, Wen-Bin Zhang, Sai Zhang, Hong-Tao Sun, Ze-Qi Yu, Hao-Xiang Xu, Yue Tu, Shi-Xiang Cheng
Article Number: 197
Published online on: 11 January 2021

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Article Open Access

Effect of long non‑coding RNA AK021443 on promoting hepatic fibrosis in vitro

Yuxin Yang, Zongsu Min
Article Number: 196
Published online on: 11 January 2021

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Article Open Access

Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways

Yousong Li, Jinsheng Gao, Xi Yang, Tao Li, Baoxue Yang, Aixingzi Aili
Article Number: 195
Published online on: 11 January 2021

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MicroRNA‑153 attenuates hypoxia‑induced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3 Corrigendum in /10.3892/mmr.2022.12848

Minjie Zhao, Wei Wang, Ya Lu, Nan Wang, Delei Kong, Lina Shan
Article Number: 194
Published online on: 07 January 2021

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Article Open Access

Bioinformatics analysis identifies biomarkers associated with poor prognosis in diffuse‑type gastric cancer

Sheng Li, Chao Yu, Yuanguang Cheng, Fangchao Du, Gang Wen
Article Number: 193
Published online on: 07 January 2021

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Genistein alleviates chronic vascular inflammatory response via the miR‑21/NF‑κB p65 axis in lipopolysaccharide‑treated mice

Xiaolin Xie, Li Cong, Sujuan Liu, Liping Xiang, Xiaohua Fu
Article Number: 192
Published online on: 07 January 2021

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Article Open Access

Long non‑coding RNA MEG3 inhibits cell migration and invasion of non‑small cell lung cancer cells by regulating the miR‑21‑5p/PTEN axis

Dongjin Lv, Qing Bi, Yunxia Li, Jie Deng, Na Wu, Shu Hao, Mingli Zhao
Article Number: 191
Published online on: 06 January 2021

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Article

Downregulation of miR‑409‑3p suppresses LPS‑induced inflammation in human bronchial epithelial cells through SOCS3/JAK1/STAT3 signaling: The implication for bronchopneumonia

Li He, Lang Tian
Article Number: 190
Published online on: 06 January 2021

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Article Open Access

miR‑212 promotes renal interstitial fibrosis by inhibiting hypoxia‑inducible factor 1‑α inhibitor

Yun Zhang, Guo-Xin Zhang, Li-Shuang Che, Shu-Han Shi, Yue-Ting Li
Article Number: 189
Published online on: 06 January 2021

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Article Open Access

Nogo‑66 promotes β‑amyloid protein secretion via NgR/ROCK‑dependent BACE1 activation

Qing-Qing Xie, Xiao Feng, Yi-Υun Huang, Nian Fang, Hua Yi, Zi-Jian Wang, Qiao-Υu Cao, Guo-Feng Lou, Jun-Ping Pan, Yang Hu, Fang-Cheng Li, Qing Zheng, Fei Xiao
Article Number: 188
Published online on: 05 January 2021

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Article Open Access

Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal cancer cells via upregulation of the microRNA-34a/449a cluster

Guangyu Ji, Wenjuan Zhou, Xian Li, Jingyi Du, Xinyue Li, Hongbo Hao
Article Number: 187
Published online on: 05 January 2021

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Article Open Access

Vascular endothelial ERp72 is involved in the inflammatory response in a rat model of skeletal muscle injury

Noureddine Ben Khalaf, Dalal Al‑Μehatab, Dahmani M. Fathallah
Article Number: 186
Published online on: 04 January 2021

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Article Open Access

Comprehensive RNA expression profile of therapeutic adipose‑derived mesenchymal stem cells co‑cultured with degenerative nucleus pulposus cells

Zhihua Han, Qiugen Wang, Xiaoming Wu, Jiandong Wang, Liang Gao, Ruipeng Guo, Jianhong Wu
Article Number: 185
Published online on: 04 January 2021

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Article

Elevation of hypertonicity‑induced protein NFAT5 promotes apoptosis of human umbilical vein endothelial cells through the NF‑κB pathway

Xupin Xie, Changpin Huang, Dong Xu, Yongchang Liu, Mengxiao Hu, Jianyun Long, Xin Fang
Article Number: 184
Published online on: 04 January 2021

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Article Open Access

Oxymatrine exerts a protective effect in myocardial ischemia/reperfusion‑induced acute lung injury by inhibiting autophagy in diabetic rats

Zhen Xiong, Jiali Xu, Xin Liu
Article Number: 183
Published online on: 04 January 2021

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Article Open Access

miR‑375 affects the hedgehog signaling pathway by downregulating RAC1 to inhibit hepatic stellate cell viability and epithelial‑mesenchymal transition

Zhiwei Liang, Jian Li, Longshuan Zhao, Yilei Deng
Article Number: 182
Published online on: 31 December 2020

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Article Open Access

9‑Hydroxy‑isoegomaketone inhibits LPS‑induced NO and inflammatory cytokine production in RAW264.7 cells

Hyun Mi Kim, Bomi Nam, Sunil Babu Paudel, Joo-Won Nam, Ah-Reum Han, Hye Gwang Jeong, Chang Hyun Jin
Article Number: 181
Published online on: 31 December 2020

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Article Open Access

Intestinal dysbacteriosis leads to kidney stone disease

Enyang Zhao, Wenfu Zhang, Bo Geng, Bosen You, Wanhui Wang, Xuedong Li
Article Number: 180
Published online on: 31 December 2020

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Review Open Access

Research progress of the transcription factor Brn4 (Review)

Yuying Wu, Xunrui Zhang, Jue Wang, Guohua Jin, Xinhua Zhang
Article Number: 179
Published online on: 31 December 2020

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Article

miR-613 inhibits the proliferation of human ovarian granulosa cells by arresting cell cycle progression via the targeting of IGF-1

Junhui Wan, Sisun Liu
Article Number: 178
Published online on: 30 December 2020

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Article

circFOXO3 protects cardiomyocytes against radiation‑induced cardiotoxicity

Yiming Qiu, Xianping Xie, Luhua Lin
Article Number: 177
Published online on: 30 December 2020

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Article Open Access

Propofol ameliorates endotoxin‑induced myocardial cell injury by inhibiting inflammation and apoptosis via the PPARγ/HMGB1/NLRP3 axis

Hui Zhao, Ying Gu, Hai Chen
Article Number: 176
Published online on: 30 December 2020

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Article Open Access

Electroacupuncture effects on the P2X4R pathway in microglia regulating the excitability of neurons in the substantia gelatinosa region of rats with spinal nerve ligation

Yuyin Zheng, Chengqian Jia, Xia Jiang, Jie Chen, Xiao-Long  Chen, Xinwang Ying, Jiayu Wu, Mingchen Jiang, Guanhu Yang, Wenzhan Tu, Kecheng Zhou, Songhe Jiang
Article Number: 175
Published online on: 30 December 2020

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Correction Open Access

[Corrigendum] Anticancer effect of quinacrine on diffuse large B‑cell lymphoma via inhibition of MSI2‑NUMB signaling pathway

Shujun Yang, Lixia Sheng, Kaihong Xu, Yi Wang, Huiling Zhu, Ping Zhang, Qitian Mu, Guifang Ouyang
Article Number: 174
Published online on: 29 December 2020

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Article Open Access

Genetic response to low‑intensity ultrasound on mouse ST2 bone marrow stromal cells

Yoshiaki Tabuchi, Hideyuki Hasegawa, Nobuo Suzuki, Yukihiro Furusawa, Tetsushi  Hirano, Ryo Nagaoka, Jun Hirayama, Nobuhiko Hoshi, Takashi Mochizuki
Article Number: 173
Published online on: 23 December 2020

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Article Open Access

MicroRNA‑149‑3p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma

Qin Shen, Hong Zhu, Qiaoling Lei, Luyuan Chen, Dajiang Yang, Wen Sui
Article Number: 172
Published online on: 23 December 2020

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Article Open Access

Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression

Xiao-Hua Zhang, Hong-Yu Zhao, Yu Wang, Lin Di, Xin-Yu Liu, Feng Qian, Shu-Rong Liu
Article Number: 171
Published online on: 23 December 2020

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Article

Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species

Yun Fu, Yuedian Ye, Guifang Zhu, Yangwei Xu, Jingbo Sun, Hongmei Wu, Feiyan Feng, Zhihui Wen, Shanshan Jiang, Yanyan Li, Qingling Zhang
Article Number: 170
Published online on: 23 December 2020

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Article Open Access

Investigating the effect of lncRNA HOTAIR on apoptosis induced by myocardial ischemia-reperfusion injury

Jijing Fang, Weihong Zheng, Pengfei Hu, Jiale Wu
Article Number: 169
Published online on: 23 December 2020

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Article Open Access

Silencing of long non‑coding RNA NEAT1 inhibits hepatocellular carcinoma progression by downregulating SMO by sponging microRNA‑503

Chuihua Sun, Ting Xiao, Ying Xiao, Yunbao Li
Article Number: 168
Published online on: 23 December 2020

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Review Open Access

Role of Wnt5a in periodontal tissue development, maintenance, and periodontitis: Implications for periodontal regeneration (Review)

Xiuqun Wei, Qian Liu, Shujuan Guo, Yafei Wu
Article Number: 167
Published online on: 23 December 2020

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Review Open Access

Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Review Open Access

Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Review Open Access

Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Review Open Access

Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Review Open Access

Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Review Open Access

Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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