Open Access

[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway

  • Authors:
    • Ning Zeng
    • Tang Hongbo
    • Yi Xu
    • Min Wu
    • Yiping Wu
  • View Affiliations

  • Published online on: March 16, 2021     https://doi.org/10.3892/mmr.2021.12011
  • Article Number: 372
  • Copyright : © Zeng et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Article

Mol Med Rep 17: [Related article:] 5652-5657, 2018; DOI: 10.3892/mmr.2018.8599

An interested reader drew to our attention that, in the above paper, several of the figures appeared to contain strikingly similar data to those published in other articles by different authors from different research institutions, including (as examples) Fig. 8 (cf. Fig. 8 in Fang, K et al: ‘Antiproliferative effects of matricine in gemcitabine-resistant human pancreatic carcinoma cells are mediated via mitochondrial-mediated apoptosis, inhibition of cell migration, invasion suppression, and mammalian target of rapamycin (mTOR)-TOR/PI3K/AKT signalling pathway’, Med Sci Monit 25: 2943-2949, 2019), Fig. 4 (cf. Fig. 7 in He, W et al: ‘Arglabin is a plant sesquiterpene lactone that exerts potent anticancer effects on human oral squamous cancer cells via mitochondrial apoptosis and downregulation of the mTOR/PI3K/Akt signaling pathway to inhibit tumor growth in vivo’, J BUON 23: 1679-1685, 2018) and Fig. 7 (cf. Fig. 7B in Yu, Y et al: ‘Globularifolin exerts anticancer effects on glioma U87 cells through inhibition of Akt/mTOR and MEK/ERK signaling pathways in vitro and inhibits tumor growth in vivo’, Biochemie 42: 144-151, 2017). The authors also independently informed the Editorial Office that they were unable to repeat the experiments shown in Fig. 4, and requested a retraction.

Given the overall problems that have come to light with this paper, the Editor of Molecular Medicine Reports has agreed with the authors that this article should be retracted from the publication. The Editor and the authors apologize for any inconvenience caused.

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May-2021
Volume 23 Issue 5

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Online ISSN:1791-3004

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Spandidos Publications style
Zeng N, Hongbo T, Xu Y, Wu M and Wu Y: [Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway. Mol Med Rep 23: 372, 2021
APA
Zeng, N., Hongbo, T., Xu, Y., Wu, M., & Wu, Y. (2021). [Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway. Molecular Medicine Reports, 23, 372. https://doi.org/10.3892/mmr.2021.12011
MLA
Zeng, N., Hongbo, T., Xu, Y., Wu, M., Wu, Y."[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway". Molecular Medicine Reports 23.5 (2021): 372.
Chicago
Zeng, N., Hongbo, T., Xu, Y., Wu, M., Wu, Y."[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway". Molecular Medicine Reports 23, no. 5 (2021): 372. https://doi.org/10.3892/mmr.2021.12011