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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-2021 Volume 23 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Role of connexins in neurodegenerative diseases (Review)

Juping Xing, Changshui Xu
Article Number: 395
Published online on: 23 March 2021

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Article Open Access

Roles of the microRNA‑338‑3p/NOVA1 axis in retinoblastoma

Shoubin Sun, Runze Wang, Sisi Yi, Sijia Li, Lei Wang, Jianwen Wang
Article Number: 394
Published online on: 22 March 2021

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Review

Advances in the study of the role and molecular mechanism of with‑no‑lysine kinase 3 in nervous system diseases (Review)

Ya-Ting Gong, Mu-Yao Wu, Jia-Feng Tang, Jin-Chao Shen, Jie  Li, Rong Gao, Bao-Qi Dang, Gang Chen
Article Number: 393
Published online on: 22 March 2021

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Article Open Access

Phosphorylated‑myosin light chain mediates the destruction of small intestinal epithelial tight junctions in mice with acute liver failure

Fan Wu, Hui Li, Heng Zhang, Yusheng Liao, Huanping Ren, Jie Wu, Dan Zheng
Article Number: 392
Published online on: 22 March 2021

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Article Open Access

Protective effects of curcumin against rat intestinal inflammation‑related motility disorders

Yang Yao, Ranyuan Luo, Shu Xiong, Chang Zhang, Yukun Zhang
Article Number: 391
Published online on: 22 March 2021

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Article Open Access

ASMq protects against early burn wound progression in rats by alleviating oxidative stress and secondary mitochondria‑associated apoptosis via the Erk/p90RSK/Bad pathway

Hanlei Zhou, Quan Fang, Nan Li, Meirong Yu, Hongming Chen, Songxue Guo
Article Number: 390
Published online on: 22 March 2021

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Article Open Access

Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway

Yafen Wang, Tianfang Chang, Tong Wu, Wei Ye, Yusheng Wang, Guorui Dou, Hongjun Du, Yannian Hui, Changmei Guo
Article Number: 389
Published online on: 22 March 2021

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Article Open Access

Long non‑coding RNA OIP5‑AS1 facilitates the progression of ovarian cancer via the miR‑128‑3p/CCNG1 axis

Yuanyuan Liu, Xiaomin Fu, Xiuyun Wang, Yanling Liu, Xiaoyan Song
Article Number: 388
Published online on: 22 March 2021

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Article Open Access

Circular RNA ABCB10 promotes cell proliferation and invasion, but inhibits apoptosis via regulating the microRNA‑1271‑mediated Capn4/Wnt/β‑catenin signaling pathway in epithelial ovarian cancer

Xuefang Lin, Yan Chen, Xiabin Ye, Xuemei Xia
Article Number: 387
Published online on: 19 March 2021

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Article Open Access

MicroRNA‑1271‑5p alleviates the malignant development of hepatitis B virus‑mediated liver cancer via binding to AQP5

Zhigang Li, Lin Ma, Lingling Di, Xutao Lin
Article Number: 386
Published online on: 19 March 2021

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Article Open Access

Tumor suppressor miR‑613 induces cisplatin sensitivity in non‑small cell lung cancer cells by targeting GJA1 Retraction in /10.3892/mmr.2024.13291

Jianhua Luo, Yan Jin, Mengyuan Li, Liyang Dong
Article Number: 385
Published online on: 18 March 2021

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Article Open Access

Functional role and molecular mechanisms underlying prohibitin 2 in platelet mitophagy and activation

Long-Long Hu, Kai Zou, Yuan Chen, Li-Juan Wu, Jie Cao, Xiao-Ying Xiong, Ling Wang, Xiao-Shu Cheng, Qing-Zhong Xiao, Ren-Qiang Yang
Article Number: 384
Published online on: 18 March 2021

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Article Open Access

MST1 inhibits the progression of breast cancer by regulating the Hippo signaling pathway and may serve as a prognostic biomarker

Xiang Jin, Lihua Zhu, Sheng Xiao, Zhuhong Cui, Jing Tang, Jiangyong Yu, Mingjun Xie
Article Number: 383
Published online on: 18 March 2021

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Review Open Access

A novel update on vitamin D in recurrent pregnancy loss (Review)

Haoyu Zhao, Xiaoqi Wei, Xiuhua Yang
Article Number: 382
Published online on: 17 March 2021

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Article Open Access

MicroRNA-124 facilitates lens epithelial cell apoptosis by inhibiting SPRY2 and MMP-2

Yan Liu, Shuting Li, Yao Liu, Xujing Lv, Qing Zhou
Article Number: 381
Published online on: 17 March 2021

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Article

Long non‑coding RNA GAS5 protects against Mycoplasma pneumoniae pneumonia by regulating the microRNA‑222‑3p/TIMP3 axis

Likun Yang, Xifeng Zhang, Xiufen Liu
Article Number: 380
Published online on: 17 March 2021

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Article Open Access

0.5‑Gy X‑ray irradiation induces reorganization of cytoskeleton and differentiation of osteoblasts

Qun Huang, Hao Chai, Shendong Wang, Yongming Sun, Wei Xu
Article Number: 379
Published online on: 17 March 2021

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Article Open Access

Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice

Lingling Pang, Pengfei Yu, Xueping Liu, Yingqi Fan, Ying Shi, Shenchun Zou
Article Number: 378
Published online on: 17 March 2021

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Article Open Access

Bakkenolide‑IIIa ameliorates lipopolysaccharide‑induced inflammatory injury in human umbilical vein endothelial cells by upregulating LINC00294

Jichong Xu, Hao Feng, Lin Ma, Huaqiao Tan, Shuo Yan, Chun Fang
Article Number: 377
Published online on: 17 March 2021

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Article Open Access

Islet transplantation ameliorates diabetes-induced testicular interstitial fibrosis and is associated with inhibition of TGF-β1/Smad2 pathway in a rat model of type 1 diabetes

Yuan-Cai Zheng, Yi-Ling Feng, Yi-Hong Wang, Li-Jun Kong, Ming-Shi Zhou, Min-Min Wu, Cheng-Yang Liu, Hua-Chun Weng, Hong-Wei Wang
Article Number: 376
Published online on: 17 March 2021

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Article Open Access

Circular RNA circ‑CCT3 promotes hepatocellular carcinoma progression by regulating the miR‑1287‑5p/TEAD1/PTCH1/LOX axis

Wennan Lin, Tianyu Zhang, Guoxu Ding, Liguo Hao, Bingquan Zhang, Jing Yu, Yu Pang, Feng Geng, Lan Zhan, Minglu Zhou, Qiyu Yan, Yuguang Wang, Chunlei Zheng, Hui Li
Article Number: 375
Published online on: 16 March 2021

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Article Open Access

Piperazine ferulate attenuates high glucose‑induced mesangial cell injury via the regulation of p66Shc

Yong-Yu Yang, Rong-Rong Deng, Zhuo Chen, Liang-Yuan Yao, Xi-Ding Yang, Da-Xiong Xiang
Article Number: 374
Published online on: 16 March 2021

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Article

Upregulation of miR‑126 inhibits podocyte injury in sepsis via EGFL6/DKC1 signaling pathway

Jianming Su, Limin Ding
Article Number: 373
Published online on: 16 March 2021

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Retraction Open Access

[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway

Ning Zeng, Tang Hongbo, Yi Xu, Min Wu, Yiping Wu
Article Number: 372
Published online on: 16 March 2021

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Article Open Access

Tanshinone IIA regulates microRNA‑125b/foxp3/caspase‑1 signaling and inhibits cell viability of nasopharyngeal carcinoma

Youhu Wang, Wenyao Jin, Junbo Wang
Article Number: 371
Published online on: 16 March 2021

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Article Open Access

Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma

Mei Li, Yu Bin Chen, Fen Liu, Jia Quan Qu, Li Cheng Ren, Jin Chai, Can E. Tang
Article Number: 370
Published online on: 16 March 2021

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Article Open Access

MicroRNA‑378d inhibits Glut4 by targeting Rsbn1 in vitamin D deficient ovarian granulosa cells

Huiting Sun, Yichao Shi, Yuwei Shang, Xia Chen, Fei Xia
Article Number: 369
Published online on: 16 March 2021

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Article Open Access

miR‑122‑5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression

Ning Hu, Yanhua Tian, Yanmei Song, Leilei Zang
Article Number: 368
Published online on: 16 March 2021

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Article Open Access

SIRT6‑specific inhibitor OSS‑128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress

Yibo Huang, Junkai Zhang, Dongdong Xu, Yu Peng, Yuan Jin, Lei Zhang
Article Number: 367
Published online on: 16 March 2021

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Article Open Access

LINC01116 promotes the proliferation and invasion of glioma by regulating the microRNA‑744‑5p‑MDM2‑p53 axis

Li Jiang, Chao Cheng, Wei Ji, Hao Wang, Quan Du, Xiaoqiao Dong, Junfei Shao, Wenhua Yu
Article Number: 366
Published online on: 16 March 2021

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Article

Protective effect of electrical stimulation of the vagus nerve in lipopolysaccharide‑induced acute lung injury in rats

Weijuan Hu, Yibing Wang, Bin Cheng, Luyang Xu, Yin Zhou, Lidong Wu
Article Number: 365
Published online on: 16 March 2021

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Review Open Access

Interaction of non‑parenchymal hepatocytes in the process of hepatic fibrosis (Review)

Qi-Ni Cheng, Xue Yang, Jiang-Feng Wu, Wen-Bing Ai, Yi-Ran Ni
Article Number: 364
Published online on: 16 March 2021

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Review

Potential role of microRNAs in the regulation of pyroptosis (Review)

Xinli Hu, Chenyu Wu, Junsheng Lou, Haiwei Ma, Xingyu Wang, Yu Xu, Yijie Chen, Sunren Sheng, Hui Xu, Huazi Xu, Xiangyang Wang, Wenfei Ni, Kailiang Zhou
Article Number: 363
Published online on: 16 March 2021

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Review Open Access

A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review)

Xianbin Kong, Peng Lu, Chuanxin Liu, Yuzhu Guo, Yuying Yang, Yingying Peng, Fangyuan Wang, Zhichao Bo, Xiaoxin Dou, Haoyang Shi, Jingyan Meng
Article Number: 362
Published online on: 16 March 2021

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Article Open Access

IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway

Ning Huang, Xing Cui, Wen Li, Chunlai Zhang, Liqing Liu, Jinxing Li
Article Number: 361
Published online on: 16 March 2021

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Article Open Access

Inhibition of chaperone‑mediated autophagy reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer

Ying Xuan, Shuang Zhao, Xingjun Xiao, Liwei Xiang, Hua-Chuan Zheng
Article Number: 360
Published online on: 12 March 2021

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Article

miR‑101‑3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF‑κB pathway

Xiaoying Zhao, Sijia Li, Zhe Wang, Ning Bai, Yuan Feng
Article Number: 359
Published online on: 12 March 2021

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Article Open Access

Hydrogen sulfide improves ox‑LDL‑induced expression levels of Lp‑PLA2 in THP‑1 monocytes via the p38MAPK pathway

Heng-Jing Hu, Jie Qiu, Chi Zhang, Zhi-Han Tang, Shun-Lin Qu, Zhi-Sheng Jiang
Article Number: 358
Published online on: 12 March 2021

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Article Open Access

miR‑320a‑3P alleviates the epithelial‑mesenchymal transition of A549 cells by activation of STAT3/SMAD3 signaling in a pulmonary fibrosis model

Xin Wang, Jing Wang, Guichuan Huang, Yishi Li, Shuliang Guo
Article Number: 357
Published online on: 12 March 2021

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Article Open Access

miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis

Hong Yang, Tianqi Hu, Panwei Hu, Cong Qi, Lin Qian
Article Number: 356
Published online on: 12 March 2021

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Article Open Access

The effect of anti‑HLA class I antibodies on the immunological properties of human glomerular endothelial cells and their modification by mTOR inhibition or GCN2 kinase activation

Theodoros Eleftheriadis, Georgios Pissas, Marta Crespo, Georgios Filippidis, Nikolaos Antoniadis, Vassilios Liakopoulos, Ioannis Stefanidis
Article Number: 355
Published online on: 12 March 2021

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Article Open Access

IDH1 gene mutation activates Smad signaling molecules to regulate the expression levels of cell cycle and biological rhythm genes in human glioma U87‑MG cells

Yongying Gao, Yanwei Wu, Ningmei Zhang, Hongmei Yuan, Fei Wang, Hui Xu, Jiaxiang Yu, Jie Ma, Shaozhang Hou, Xiangmei Cao
Article Number: 354
Published online on: 12 March 2021

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Article

miR‑519d‑3p/HIF‑2α axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling

Lixia Jiang, Shaohua Shi, Feng Li, Qiaofa Shi, Tianyu Zhong, Huijuan Zhang, Yu Xia
Article Number: 353
Published online on: 12 March 2021

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Review Open Access

HIF‑1α in myocardial ischemia‑reperfusion injury (Review)

Jie Zheng, Peier Chen, Jianfeng Zhong, Yu Cheng, Hao Chen, Yuan He, Can Chen
Article Number: 352
Published online on: 12 March 2021

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Case Report Open Access

Updates in neonatal coronavirus disease 2019: What can we learn from detailed case reports? (Review)

Xingchao Li, Li Sun, Tao Li
Article Number: 351
Published online on: 11 March 2021

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Article Open Access

Berberine ameliorates the LPS-induced imbalance of osteogenic and adipogenic differentiation in rat bone marrow-derived mesenchymal stem cells

Rong Zhou, Fubo Chen, Haixia Liu, Xueqin Zhu, Xueyun Wen, Fang Yu, Guangwei Shang, Shengcai Qi, Yuanzhi Xu
Article Number: 350
Published online on: 11 March 2021

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Article Open Access

Circular RNA hsa_circ_0072309 inhibits the proliferation, invasion and migration of gastric cancer cells via inhibition of PI3K/AKT signaling by activating PPARγ/PTEN signaling

Xingpo Guo, Mingde Qin, Han Hong, Xiaofeng Xue, Jian Fang, Linhua Jiang, Yuting Kuang, Ling Gao
Article Number: 349
Published online on: 11 March 2021

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Article

Salvia miltiorrhiza induces depolarization of pacemaker potentials in murine small intestinal interstitial cells of Cajal via extracellular Ca2+ and Na+ influx

Donghun Han, Jeong Nam Kim, Min Ji Kwon, Taewon Han, Yun Tai Kim, Byung Joo Kim
Article Number: 348
Published online on: 11 March 2021

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Review Open Access

Interplay between cyclooxygenase‑2 and microRNAs in cancer (Review)

Zexiong Gong, Weiguo Huang, Baiyun Wang, Na Liang, Songkai Long, Wanjun Li, Qier Zhou
Article Number: 347
Published online on: 11 March 2021

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Article Open Access

miR‑224‑5p regulates the proliferation, migration and invasion of pancreatic mucinous cystadenocarcinoma by targeting PTEN

Xiaobo Peng, Chengtao Guo, Yanjun Wu, Mingzhen Ying, Renxu Chang, Lele Song, Lixing Zhan, Xianbao Zhan
Article Number: 346
Published online on: 10 March 2021

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Article Open Access

Total flavonoids of Rhizoma drynariae ameliorate steroid‑induced avascular necrosis of the femoral head via the PI3K/AKT pathway

Wenxue Lv, Mingxiu Yu, Qingyi Yang, Peng Kong, Bing Yan
Article Number: 345
Published online on: 09 March 2021

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Article Open Access

Cytokine secretion and pyroptosis of cholesteatoma keratinocytes mediated by AIM2 inflammasomes in response to cytoplasmic DNA

Chen Zhang, Min Chen, Zhangcai Chi
Article Number: 344
Published online on: 09 March 2021

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Article Open Access

HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin Corrigendum in /10.3892/mmr.2021.12143

Zengpeng Sun, Zhiguo Tan, Chuang Peng, Weimin Yi
Article Number: 343
Published online on: 09 March 2021

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Article

SERPINE2 feedback regulates EGF/EGFR signaling in human papillary thyroid carcinoma cells

Huimin Chu, Bo Hu, Xinyu Su
Article Number: 342
Published online on: 09 March 2021

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Article Open Access

Exogenous melatonin alleviates hemorrhagic shock‑induced hepatic ischemic injury in rats by inhibiting the NF‑κB/IκBα signaling pathway

Hai‑Wei Li, Pan Ying, Qi‑Qi Cai, Zhi‑Hui Yang, Xian‑Long Wu
Article Number: 341
Published online on: 09 March 2021

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Article Open Access

linc‑ROR facilitates hepatocellular carcinoma resistance to doxorubicin by regulating TWIST1‑mediated epithelial‑mesenchymal transition

Yuanbiao Zhang, Weiding Wu, Qiang Sun, Longyun Ye, Dongkai Zhou, Weilin Wang
Article Number: 340
Published online on: 09 March 2021

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Article

Protective effect of trichostatin A on CD19+CD5+CD1dhigh regulatory B cells in heart transplantation

Bing Zhou, Fuyang Mei, Changhao Wu, Heyun Xu, Zhifang Liu, Yong Cui
Article Number: 339
Published online on: 09 March 2021

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Article Open Access

Cyanidin‑3‑O‑β‑glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF‑β1/p38 MAPK/CREB signaling pathway

Shao Ouyang, Wei Chen, Zeng Gaofeng, Lei Changcheng, Tian Guoping, Zhu Minyan, Liu Yang, Yang Min, Jiahao Luo
Article Number: 338
Published online on: 09 March 2021

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Article

Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis

Jun-Hua Huang, Hua Duan, Sha Wang, Yi-Yi Wang
Article Number: 337
Published online on: 08 March 2021

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Article Open Access

Tumor suppressor role of sFRP‑4 in hepatocellular carcinoma via the Wnt/β‑catenin signaling pathway

Quanxin Wu, Cheng Xu, Xianghua Zeng, Zhimin Zhang, Bo Yang, Zhiguo Rao
Article Number: 336
Published online on: 08 March 2021

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Article Open Access

Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study

Liying Yang, Qianqian Liu, He Zhang, Yichao Wang, Yang Li, Shuchun Chen, Guangyao Song, Luping Ren
Article Number: 335
Published online on: 08 March 2021

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Article Open Access

Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction

Chao Chang, Liya Hu, Shanshan Sun, Yanqiu Song, Shan Liu, Jing Wang, Peijun Li
Article Number: 334
Published online on: 08 March 2021

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Article Open Access

Propofol alleviates inflammation and apoptosis in HCY‑induced HUVECs by inhibiting endoplasmic reticulum stress

Cunliang Ji, Hu Yi, Jing Huang, Wenzhong Zhang, Mingzhi Zheng
Article Number: 333
Published online on: 08 March 2021

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Article Open Access

Naringin ameliorates memory deficits and exerts neuroprotective effects in a mouse model of Alzheimer's disease by regulating multiple metabolic pathways

Xiangdong Meng, Mingming Fu, Shoufeng Wang, Weida Chen, Jianjie Wang, Ning Zhang
Article Number: 332
Published online on: 08 March 2021

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Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling

Baitao Ma, Xuebin Wang, Rui Zhang, Shuai Niu, Zhihua  Rong, Leng Ni, Xiao Di, Qin Han, Changwei Liu
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Acute glucose fluctuation promotes RAGE expression via reactive oxygen species‑mediated NF‑κB activation in rat podocytes

Zhangjie Hu, Wenming Fang, Yi Liu, Haowei Liang, Wei Chen, Hui Wang
Article Number: 330
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miR-93-5p promotes insulin resistance to regulate type 2 diabetes progression in HepG2 cells by targeting HGF

Man Zhou, Yilin Hou, Jun Wu, Guangli Li, Ping Cao, Wan Chen, Lingli Hu, Dingyun Gan
Article Number: 329
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Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA

Qiang Cheng, Qiang Li, Lingen Xu, Hui Jiang
Article Number: 328
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Expression of immunoglobulin G in human proximal tubular epithelial cells

Zhenling Deng, Ziyang Jing, Yanhong Guo, Junfan Ma, Huige Yan, Zhan Shi, Hui Deng, Yaoxian Liang, Song Wang, Zhuan Cui, Yuejuan Pan, Xiaoyan Qiu, Yue Wang
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HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro

Dongjie Sun, Zhehao Huang, Jinying Xu, Yiqing Wang, Lin Chen, Yi Hou, Guangfan Chi
Article Number: 326
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Application of nanotechnology in drug delivery systems for respiratory diseases (Review)

Ming-Xin Luo, Shan Hua, Qi-Yun Shang
Article Number: 325
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Circular RNA_0074027 participates in cell proliferation, apoptosis and metastasis of colorectal cancer cells through regulation of miR‑525‑3p

Gang Xiong, Jun Zhang, Yichao Zhang, Xiao Pang, Biao Wang, Yongchuan Zhang
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lncRNA‑MIAT facilitates the differentiation of adipose‑derived mesenchymal stem cells into lymphatic endothelial cells via the miR‑495/Prox1 axis

Xiao-Wei Dai, Wen Luo, Chun-Liu Lv
Article Number: 323
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miR‑302c‑3p and miR‑520a‑3p suppress the proliferation of cervical carcinoma cells by targeting CXCL8

Hong-Mei Ding, Hong Zhang, Juan Wang, Jin-Hua Zhou, Fang-Rong Shen, Ru-Ning Ji, Jia-Yin Shi, You-Guo Chen
Article Number: 322
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Impaired activity of circulating EPCs and endothelial function are associated with increased Syntax score in patients with coronary artery disease

Bin Zhang, Dong Li, Gexiu Liu, Wenfeng Tan, Gaoxing Zhang, Jinli Liao
Article Number: 321
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Corilagin induces apoptosis and autophagy in NRF2‑addicted U251 glioma cell line

Jilan Liu, Xianyun Qin, Wenyuan Ma, Shu Jia, Xiaobei Zhang, Xinlin Yang, Dongfeng Pan, Feng Jin
Article Number: 320
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Serum from patients with hypertension promotes endothelial dysfunction to induce trophoblast invasion through the miR‑27b‑3p/ATPase plasma membrane Ca2+ transporting 1 axis

Libo Zhu, Zhuqing Liu
Article Number: 319
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lncRNA DQ786243 promotes hepatocellular carcinoma cell invasion and proliferation by regulating the miR‑15b‑5p/Wnt3A axis Corrigendum in /10.3892/mmr.2022.12912 Retraction in /10.3892/mmr.2024.13399

Zewei Lin, Jikui Liu
Article Number: 318
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Testis-expressed protein 33 is not essential for spermiogenesis and fertility in mice

Mengmeng Xia, Jing Xia, Changmin Niu, Yanan Zhong, Tingting Ge, Yue Ding, Ying Zheng
Article Number: 317
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MicroRNA‑181a promotes epithelial‑mesenchymal transition in esophageal squamous cell carcinoma via the TGF‑β/Smad pathway

Run Xu, Xue-Mei Zhou, Yu-Shan Li, Li Ren, Xin-Rong He
Article Number: 316
Published online on: 02 March 2021

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Synergistic effect of the herbal mixture C5E on gemcitabine treatment in PANC‑1 cells

Pyo June Pak, Dong Gun Lee, Ji Hyun Sung, Seung Hyun Jung, Tae-Young Han, Sung Hyo Park, Namhyun Chung
Article Number: 315
Published online on: 02 March 2021

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Protective effects of different anti‑inflammatory drugs on tracheal stenosis following injury and potential mechanisms

Zhenjie Huang, Peng Wei, Luoman Gan, Wentao Li, Tonghua Zeng, Caicheng Qin, Zhiyu Chen, Guangnan Liu
Article Number: 314
Published online on: 02 March 2021

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Therapeutic effects of quinine in a mouse model of atopic dermatitis

Qian Zhang, Hongjing Jiang, Miao Liu, Xinchen Li, Murong Zhou, Yansi Lyu, Jingkai Huang, Si Chen, Li Wang
Article Number: 313
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miR‑541‑3p inhibits the viability and migration of vascular smooth muscle cells via targeting STIM1

Zhiyu Lv, Dengliang Yi, Chi Zhang, Yujie Xie, He Huang, Zhongcai Fan, Xing Liu
Article Number: 312
Published online on: 02 March 2021

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circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis

Yan Wen, Yao Chun, Zhong Qing Lian, Zhang Wei Yong, Yang Mei Lan, Liao Huan, Chen Yi Xi, Li Shu Juan, Zhong Wen Qing, Cheng Jia, Zhang Huan Ji
Article Number: 311
Published online on: 01 March 2021

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GASC1 promotes glioma progression by enhancing NOTCH1 signaling

Zhengzheng Xiao, Xiaoli Yang, Zebin Liu, Zheng Shao, Chaojun  Song, Kun Zhang, Xiaobin Wang, Zhengwei Li
Article Number: 310
Published online on: 28 February 2021

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Downregulation of lncRNA RPLP0P2 inhibits cell proliferation, invasion and migration, and promotes apoptosis in colorectal cancer

Hang Yuan, Shiliang Tu, Yingyu Ma, Yueming Sun
Article Number: 309
Published online on: 28 February 2021

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Chidamide induces apoptosis in DLBCL cells by suppressing the HDACs/STAT3/Bcl‑2 pathway

Hongwei Zhang, Fenqing Chi, Keru Qin, Xiuli Mu, Lieyang Wang, Bin  Yang, Yanli Wang, Min Bai, Zhenhua Li, Liping Su, Baofeng Yu
Article Number: 308
Published online on: 26 February 2021

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Functions of circular RNAs in bladder, prostate and renal cell cancer (Review)

Longfei Yang, Xiaofeng Zou, Junrong Zou, Guoxi Zhang
Article Number: 307
Published online on: 26 February 2021

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20(s)‑ginseonside‑Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone‑injured C2C12 myotube‑based model of skeletal atrophy in vitro Corrigendum in /10.3892/mmr.2021.12259

Manying Wang, Rui Jiang, Jianzeng Liu, Xiaohao Xu, Guang Sun, Daqing Zhao, Liwei Sun
Article Number: 306
Published online on: 26 February 2021

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Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation

He-Ming Huang, Xiao-Ru Zhou, Yan-Jun Liu, Shi-Jie Fan, Li-Ping Liao, Jing Huang, Cui-Cui Shi, Liang Yu, Jin-Jin Pen, Cheng Luo, Yuan-Yuan Zhang, Guang-Ming Li
Article Number: 305
Published online on: 26 February 2021

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MicroRNA‑199a/b‑5p inhibits endometrial cancer cell metastasis and invasion by targeting FAM83B in the epithelial‑to‑mesenchymal transition signaling pathway

Hanzhen Xiong, Na Wang, Hui Chen, Minfen Zhang, Qiongyan Lin
Article Number: 304
Published online on: 26 February 2021

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miR‑875‑5p regulates IR and inflammation via targeting TXNRD1 in gestational diabetes rats

Songbo Fu, Songquan Fu, Xiaoni Ma, Xiaomei Yang, Jizu Ling
Article Number: 303
Published online on: 25 February 2021

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June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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