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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-2021 Volume 23 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Role of connexins in neurodegenerative diseases (Review)

Juping Xing, Changshui Xu
Article Number: 395
Published online on: 23 March 2021

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Article Open Access

Roles of the microRNA‑338‑3p/NOVA1 axis in retinoblastoma

Shoubin Sun, Runze Wang, Sisi Yi, Sijia Li, Lei Wang, Jianwen Wang
Article Number: 394
Published online on: 22 March 2021

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Review

Advances in the study of the role and molecular mechanism of with‑no‑lysine kinase 3 in nervous system diseases (Review)

Ya-Ting Gong, Mu-Yao Wu, Jia-Feng Tang, Jin-Chao Shen, Jie  Li, Rong Gao, Bao-Qi Dang, Gang Chen
Article Number: 393
Published online on: 22 March 2021

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Article Open Access

Phosphorylated‑myosin light chain mediates the destruction of small intestinal epithelial tight junctions in mice with acute liver failure

Fan Wu, Hui Li, Heng Zhang, Yusheng Liao, Huanping Ren, Jie Wu, Dan Zheng
Article Number: 392
Published online on: 22 March 2021

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Article Open Access

Protective effects of curcumin against rat intestinal inflammation‑related motility disorders

Yang Yao, Ranyuan Luo, Shu Xiong, Chang Zhang, Yukun Zhang
Article Number: 391
Published online on: 22 March 2021

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Article Open Access

ASMq protects against early burn wound progression in rats by alleviating oxidative stress and secondary mitochondria‑associated apoptosis via the Erk/p90RSK/Bad pathway

Hanlei Zhou, Quan Fang, Nan Li, Meirong Yu, Hongming Chen, Songxue Guo
Article Number: 390
Published online on: 22 March 2021

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Article Open Access

Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway

Yafen Wang, Tianfang Chang, Tong Wu, Wei Ye, Yusheng Wang, Guorui Dou, Hongjun Du, Yannian Hui, Changmei Guo
Article Number: 389
Published online on: 22 March 2021

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Article Open Access

Long non‑coding RNA OIP5‑AS1 facilitates the progression of ovarian cancer via the miR‑128‑3p/CCNG1 axis

Yuanyuan Liu, Xiaomin Fu, Xiuyun Wang, Yanling Liu, Xiaoyan Song
Article Number: 388
Published online on: 22 March 2021

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Article Open Access

Circular RNA ABCB10 promotes cell proliferation and invasion, but inhibits apoptosis via regulating the microRNA‑1271‑mediated Capn4/Wnt/β‑catenin signaling pathway in epithelial ovarian cancer

Xuefang Lin, Yan Chen, Xiabin Ye, Xuemei Xia
Article Number: 387
Published online on: 19 March 2021

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Article Open Access

MicroRNA‑1271‑5p alleviates the malignant development of hepatitis B virus‑mediated liver cancer via binding to AQP5

Zhigang Li, Lin Ma, Lingling Di, Xutao Lin
Article Number: 386
Published online on: 19 March 2021

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Article Open Access

Tumor suppressor miR‑613 induces cisplatin sensitivity in non‑small cell lung cancer cells by targeting GJA1 Retraction in /10.3892/mmr.2024.13291

Jianhua Luo, Yan Jin, Mengyuan Li, Liyang Dong
Article Number: 385
Published online on: 18 March 2021

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Article Open Access

Functional role and molecular mechanisms underlying prohibitin 2 in platelet mitophagy and activation

Long-Long Hu, Kai Zou, Yuan Chen, Li-Juan Wu, Jie Cao, Xiao-Ying Xiong, Ling Wang, Xiao-Shu Cheng, Qing-Zhong Xiao, Ren-Qiang Yang
Article Number: 384
Published online on: 18 March 2021

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Article Open Access

MST1 inhibits the progression of breast cancer by regulating the Hippo signaling pathway and may serve as a prognostic biomarker

Xiang Jin, Lihua Zhu, Sheng Xiao, Zhuhong Cui, Jing Tang, Jiangyong Yu, Mingjun Xie
Article Number: 383
Published online on: 18 March 2021

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Review Open Access

A novel update on vitamin D in recurrent pregnancy loss (Review)

Haoyu Zhao, Xiaoqi Wei, Xiuhua Yang
Article Number: 382
Published online on: 17 March 2021

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Article Open Access

MicroRNA-124 facilitates lens epithelial cell apoptosis by inhibiting SPRY2 and MMP-2

Yan Liu, Shuting Li, Yao Liu, Xujing Lv, Qing Zhou
Article Number: 381
Published online on: 17 March 2021

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Article

Long non‑coding RNA GAS5 protects against Mycoplasma pneumoniae pneumonia by regulating the microRNA‑222‑3p/TIMP3 axis

Likun Yang, Xifeng Zhang, Xiufen Liu
Article Number: 380
Published online on: 17 March 2021

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Article Open Access

0.5‑Gy X‑ray irradiation induces reorganization of cytoskeleton and differentiation of osteoblasts

Qun Huang, Hao Chai, Shendong Wang, Yongming Sun, Wei Xu
Article Number: 379
Published online on: 17 March 2021

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Article Open Access

Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice

Lingling Pang, Pengfei Yu, Xueping Liu, Yingqi Fan, Ying Shi, Shenchun Zou
Article Number: 378
Published online on: 17 March 2021

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Article Open Access

Bakkenolide‑IIIa ameliorates lipopolysaccharide‑induced inflammatory injury in human umbilical vein endothelial cells by upregulating LINC00294

Jichong Xu, Hao Feng, Lin Ma, Huaqiao Tan, Shuo Yan, Chun Fang
Article Number: 377
Published online on: 17 March 2021

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Article Open Access

Islet transplantation ameliorates diabetes-induced testicular interstitial fibrosis and is associated with inhibition of TGF-β1/Smad2 pathway in a rat model of type 1 diabetes

Yuan-Cai Zheng, Yi-Ling Feng, Yi-Hong Wang, Li-Jun Kong, Ming-Shi Zhou, Min-Min Wu, Cheng-Yang Liu, Hua-Chun Weng, Hong-Wei Wang
Article Number: 376
Published online on: 17 March 2021

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Article Open Access

Circular RNA circ‑CCT3 promotes hepatocellular carcinoma progression by regulating the miR‑1287‑5p/TEAD1/PTCH1/LOX axis

Wennan Lin, Tianyu Zhang, Guoxu Ding, Liguo Hao, Bingquan Zhang, Jing Yu, Yu Pang, Feng Geng, Lan Zhan, Minglu Zhou, Qiyu Yan, Yuguang Wang, Chunlei Zheng, Hui Li
Article Number: 375
Published online on: 16 March 2021

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Article Open Access

Piperazine ferulate attenuates high glucose‑induced mesangial cell injury via the regulation of p66Shc

Yong-Yu Yang, Rong-Rong Deng, Zhuo Chen, Liang-Yuan Yao, Xi-Ding Yang, Da-Xiong Xiang
Article Number: 374
Published online on: 16 March 2021

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Article

Upregulation of miR‑126 inhibits podocyte injury in sepsis via EGFL6/DKC1 signaling pathway

Jianming Su, Limin Ding
Article Number: 373
Published online on: 16 March 2021

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Retraction Open Access

[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway

Ning Zeng, Tang Hongbo, Yi Xu, Min Wu, Yiping Wu
Article Number: 372
Published online on: 16 March 2021

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Article Open Access

Tanshinone IIA regulates microRNA‑125b/foxp3/caspase‑1 signaling and inhibits cell viability of nasopharyngeal carcinoma

Youhu Wang, Wenyao Jin, Junbo Wang
Article Number: 371
Published online on: 16 March 2021

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Article Open Access

Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma

Mei Li, Yu Bin Chen, Fen Liu, Jia Quan Qu, Li Cheng Ren, Jin Chai, Can E. Tang
Article Number: 370
Published online on: 16 March 2021

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Article Open Access

MicroRNA‑378d inhibits Glut4 by targeting Rsbn1 in vitamin D deficient ovarian granulosa cells

Huiting Sun, Yichao Shi, Yuwei Shang, Xia Chen, Fei Xia
Article Number: 369
Published online on: 16 March 2021

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Article Open Access

miR‑122‑5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression

Ning Hu, Yanhua Tian, Yanmei Song, Leilei Zang
Article Number: 368
Published online on: 16 March 2021

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Article Open Access

SIRT6‑specific inhibitor OSS‑128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress

Yibo Huang, Junkai Zhang, Dongdong Xu, Yu Peng, Yuan Jin, Lei Zhang
Article Number: 367
Published online on: 16 March 2021

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Article Open Access

LINC01116 promotes the proliferation and invasion of glioma by regulating the microRNA‑744‑5p‑MDM2‑p53 axis

Li Jiang, Chao Cheng, Wei Ji, Hao Wang, Quan Du, Xiaoqiao Dong, Junfei Shao, Wenhua Yu
Article Number: 366
Published online on: 16 March 2021

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Article

Protective effect of electrical stimulation of the vagus nerve in lipopolysaccharide‑induced acute lung injury in rats

Weijuan Hu, Yibing Wang, Bin Cheng, Luyang Xu, Yin Zhou, Lidong Wu
Article Number: 365
Published online on: 16 March 2021

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Review Open Access

Interaction of non‑parenchymal hepatocytes in the process of hepatic fibrosis (Review)

Qi-Ni Cheng, Xue Yang, Jiang-Feng Wu, Wen-Bing Ai, Yi-Ran Ni
Article Number: 364
Published online on: 16 March 2021

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Review

Potential role of microRNAs in the regulation of pyroptosis (Review)

Xinli Hu, Chenyu Wu, Junsheng Lou, Haiwei Ma, Xingyu Wang, Yu Xu, Yijie Chen, Sunren Sheng, Hui Xu, Huazi Xu, Xiangyang Wang, Wenfei Ni, Kailiang Zhou
Article Number: 363
Published online on: 16 March 2021

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Review Open Access

A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review)

Xianbin Kong, Peng Lu, Chuanxin Liu, Yuzhu Guo, Yuying Yang, Yingying Peng, Fangyuan Wang, Zhichao Bo, Xiaoxin Dou, Haoyang Shi, Jingyan Meng
Article Number: 362
Published online on: 16 March 2021

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Article Open Access

IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway

Ning Huang, Xing Cui, Wen Li, Chunlai Zhang, Liqing Liu, Jinxing Li
Article Number: 361
Published online on: 16 March 2021

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Article Open Access

Inhibition of chaperone‑mediated autophagy reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer

Ying Xuan, Shuang Zhao, Xingjun Xiao, Liwei Xiang, Hua-Chuan Zheng
Article Number: 360
Published online on: 12 March 2021

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Article

miR‑101‑3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF‑κB pathway

Xiaoying Zhao, Sijia Li, Zhe Wang, Ning Bai, Yuan Feng
Article Number: 359
Published online on: 12 March 2021

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Article Open Access

Hydrogen sulfide improves ox‑LDL‑induced expression levels of Lp‑PLA2 in THP‑1 monocytes via the p38MAPK pathway

Heng-Jing Hu, Jie Qiu, Chi Zhang, Zhi-Han Tang, Shun-Lin Qu, Zhi-Sheng Jiang
Article Number: 358
Published online on: 12 March 2021

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Article Open Access

miR‑320a‑3P alleviates the epithelial‑mesenchymal transition of A549 cells by activation of STAT3/SMAD3 signaling in a pulmonary fibrosis model

Xin Wang, Jing Wang, Guichuan Huang, Yishi Li, Shuliang Guo
Article Number: 357
Published online on: 12 March 2021

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Article Open Access

miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis

Hong Yang, Tianqi Hu, Panwei Hu, Cong Qi, Lin Qian
Article Number: 356
Published online on: 12 March 2021

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Article Open Access

The effect of anti‑HLA class I antibodies on the immunological properties of human glomerular endothelial cells and their modification by mTOR inhibition or GCN2 kinase activation

Theodoros Eleftheriadis, Georgios Pissas, Marta Crespo, Georgios Filippidis, Nikolaos Antoniadis, Vassilios Liakopoulos, Ioannis Stefanidis
Article Number: 355
Published online on: 12 March 2021

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Article Open Access

IDH1 gene mutation activates Smad signaling molecules to regulate the expression levels of cell cycle and biological rhythm genes in human glioma U87‑MG cells

Yongying Gao, Yanwei Wu, Ningmei Zhang, Hongmei Yuan, Fei Wang, Hui Xu, Jiaxiang Yu, Jie Ma, Shaozhang Hou, Xiangmei Cao
Article Number: 354
Published online on: 12 March 2021

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Article

miR‑519d‑3p/HIF‑2α axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling

Lixia Jiang, Shaohua Shi, Feng Li, Qiaofa Shi, Tianyu Zhong, Huijuan Zhang, Yu Xia
Article Number: 353
Published online on: 12 March 2021

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Review Open Access

HIF‑1α in myocardial ischemia‑reperfusion injury (Review)

Jie Zheng, Peier Chen, Jianfeng Zhong, Yu Cheng, Hao Chen, Yuan He, Can Chen
Article Number: 352
Published online on: 12 March 2021

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Case Report Open Access

Updates in neonatal coronavirus disease 2019: What can we learn from detailed case reports? (Review)

Xingchao Li, Li Sun, Tao Li
Article Number: 351
Published online on: 11 March 2021

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Article Open Access

Berberine ameliorates the LPS-induced imbalance of osteogenic and adipogenic differentiation in rat bone marrow-derived mesenchymal stem cells

Rong Zhou, Fubo Chen, Haixia Liu, Xueqin Zhu, Xueyun Wen, Fang Yu, Guangwei Shang, Shengcai Qi, Yuanzhi Xu
Article Number: 350
Published online on: 11 March 2021

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Article Open Access

Circular RNA hsa_circ_0072309 inhibits the proliferation, invasion and migration of gastric cancer cells via inhibition of PI3K/AKT signaling by activating PPARγ/PTEN signaling

Xingpo Guo, Mingde Qin, Han Hong, Xiaofeng Xue, Jian Fang, Linhua Jiang, Yuting Kuang, Ling Gao
Article Number: 349
Published online on: 11 March 2021

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Article

Salvia miltiorrhiza induces depolarization of pacemaker potentials in murine small intestinal interstitial cells of Cajal via extracellular Ca2+ and Na+ influx

Donghun Han, Jeong Nam Kim, Min Ji Kwon, Taewon Han, Yun Tai Kim, Byung Joo Kim
Article Number: 348
Published online on: 11 March 2021

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Review Open Access

Interplay between cyclooxygenase‑2 and microRNAs in cancer (Review)

Zexiong Gong, Weiguo Huang, Baiyun Wang, Na Liang, Songkai Long, Wanjun Li, Qier Zhou
Article Number: 347
Published online on: 11 March 2021

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Article Open Access

miR‑224‑5p regulates the proliferation, migration and invasion of pancreatic mucinous cystadenocarcinoma by targeting PTEN

Xiaobo Peng, Chengtao Guo, Yanjun Wu, Mingzhen Ying, Renxu Chang, Lele Song, Lixing Zhan, Xianbao Zhan
Article Number: 346
Published online on: 10 March 2021

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Article Open Access

Total flavonoids of Rhizoma drynariae ameliorate steroid‑induced avascular necrosis of the femoral head via the PI3K/AKT pathway

Wenxue Lv, Mingxiu Yu, Qingyi Yang, Peng Kong, Bing Yan
Article Number: 345
Published online on: 09 March 2021

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Article Open Access

Cytokine secretion and pyroptosis of cholesteatoma keratinocytes mediated by AIM2 inflammasomes in response to cytoplasmic DNA

Chen Zhang, Min Chen, Zhangcai Chi
Article Number: 344
Published online on: 09 March 2021

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Article Open Access

HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin Corrigendum in /10.3892/mmr.2021.12143

Zengpeng Sun, Zhiguo Tan, Chuang Peng, Weimin Yi
Article Number: 343
Published online on: 09 March 2021

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Article

SERPINE2 feedback regulates EGF/EGFR signaling in human papillary thyroid carcinoma cells

Huimin Chu, Bo Hu, Xinyu Su
Article Number: 342
Published online on: 09 March 2021

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Article Open Access

Exogenous melatonin alleviates hemorrhagic shock‑induced hepatic ischemic injury in rats by inhibiting the NF‑κB/IκBα signaling pathway

Hai‑Wei Li, Pan Ying, Qi‑Qi Cai, Zhi‑Hui Yang, Xian‑Long Wu
Article Number: 341
Published online on: 09 March 2021

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Article Open Access

linc‑ROR facilitates hepatocellular carcinoma resistance to doxorubicin by regulating TWIST1‑mediated epithelial‑mesenchymal transition

Yuanbiao Zhang, Weiding Wu, Qiang Sun, Longyun Ye, Dongkai Zhou, Weilin Wang
Article Number: 340
Published online on: 09 March 2021

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Article

Protective effect of trichostatin A on CD19+CD5+CD1dhigh regulatory B cells in heart transplantation

Bing Zhou, Fuyang Mei, Changhao Wu, Heyun Xu, Zhifang Liu, Yong Cui
Article Number: 339
Published online on: 09 March 2021

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Article Open Access

Cyanidin‑3‑O‑β‑glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF‑β1/p38 MAPK/CREB signaling pathway

Shao Ouyang, Wei Chen, Zeng Gaofeng, Lei Changcheng, Tian Guoping, Zhu Minyan, Liu Yang, Yang Min, Jiahao Luo
Article Number: 338
Published online on: 09 March 2021

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Article

Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis

Jun-Hua Huang, Hua Duan, Sha Wang, Yi-Yi Wang
Article Number: 337
Published online on: 08 March 2021

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Article Open Access

Tumor suppressor role of sFRP‑4 in hepatocellular carcinoma via the Wnt/β‑catenin signaling pathway

Quanxin Wu, Cheng Xu, Xianghua Zeng, Zhimin Zhang, Bo Yang, Zhiguo Rao
Article Number: 336
Published online on: 08 March 2021

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Article Open Access

Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study

Liying Yang, Qianqian Liu, He Zhang, Yichao Wang, Yang Li, Shuchun Chen, Guangyao Song, Luping Ren
Article Number: 335
Published online on: 08 March 2021

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Article Open Access

Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction

Chao Chang, Liya Hu, Shanshan Sun, Yanqiu Song, Shan Liu, Jing Wang, Peijun Li
Article Number: 334
Published online on: 08 March 2021

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Article Open Access

Propofol alleviates inflammation and apoptosis in HCY‑induced HUVECs by inhibiting endoplasmic reticulum stress

Cunliang Ji, Hu Yi, Jing Huang, Wenzhong Zhang, Mingzhi Zheng
Article Number: 333
Published online on: 08 March 2021

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Article Open Access

Naringin ameliorates memory deficits and exerts neuroprotective effects in a mouse model of Alzheimer's disease by regulating multiple metabolic pathways

Xiangdong Meng, Mingming Fu, Shoufeng Wang, Weida Chen, Jianjie Wang, Ning Zhang
Article Number: 332
Published online on: 08 March 2021

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Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling

Baitao Ma, Xuebin Wang, Rui Zhang, Shuai Niu, Zhihua  Rong, Leng Ni, Xiao Di, Qin Han, Changwei Liu
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Acute glucose fluctuation promotes RAGE expression via reactive oxygen species‑mediated NF‑κB activation in rat podocytes

Zhangjie Hu, Wenming Fang, Yi Liu, Haowei Liang, Wei Chen, Hui Wang
Article Number: 330
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miR-93-5p promotes insulin resistance to regulate type 2 diabetes progression in HepG2 cells by targeting HGF

Man Zhou, Yilin Hou, Jun Wu, Guangli Li, Ping Cao, Wan Chen, Lingli Hu, Dingyun Gan
Article Number: 329
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Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA

Qiang Cheng, Qiang Li, Lingen Xu, Hui Jiang
Article Number: 328
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Expression of immunoglobulin G in human proximal tubular epithelial cells

Zhenling Deng, Ziyang Jing, Yanhong Guo, Junfan Ma, Huige Yan, Zhan Shi, Hui Deng, Yaoxian Liang, Song Wang, Zhuan Cui, Yuejuan Pan, Xiaoyan Qiu, Yue Wang
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HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro

Dongjie Sun, Zhehao Huang, Jinying Xu, Yiqing Wang, Lin Chen, Yi Hou, Guangfan Chi
Article Number: 326
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Application of nanotechnology in drug delivery systems for respiratory diseases (Review)

Ming-Xin Luo, Shan Hua, Qi-Yun Shang
Article Number: 325
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Circular RNA_0074027 participates in cell proliferation, apoptosis and metastasis of colorectal cancer cells through regulation of miR‑525‑3p

Gang Xiong, Jun Zhang, Yichao Zhang, Xiao Pang, Biao Wang, Yongchuan Zhang
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lncRNA‑MIAT facilitates the differentiation of adipose‑derived mesenchymal stem cells into lymphatic endothelial cells via the miR‑495/Prox1 axis

Xiao-Wei Dai, Wen Luo, Chun-Liu Lv
Article Number: 323
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miR‑302c‑3p and miR‑520a‑3p suppress the proliferation of cervical carcinoma cells by targeting CXCL8

Hong-Mei Ding, Hong Zhang, Juan Wang, Jin-Hua Zhou, Fang-Rong Shen, Ru-Ning Ji, Jia-Yin Shi, You-Guo Chen
Article Number: 322
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Impaired activity of circulating EPCs and endothelial function are associated with increased Syntax score in patients with coronary artery disease

Bin Zhang, Dong Li, Gexiu Liu, Wenfeng Tan, Gaoxing Zhang, Jinli Liao
Article Number: 321
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Corilagin induces apoptosis and autophagy in NRF2‑addicted U251 glioma cell line

Jilan Liu, Xianyun Qin, Wenyuan Ma, Shu Jia, Xiaobei Zhang, Xinlin Yang, Dongfeng Pan, Feng Jin
Article Number: 320
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Serum from patients with hypertension promotes endothelial dysfunction to induce trophoblast invasion through the miR‑27b‑3p/ATPase plasma membrane Ca2+ transporting 1 axis

Libo Zhu, Zhuqing Liu
Article Number: 319
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lncRNA DQ786243 promotes hepatocellular carcinoma cell invasion and proliferation by regulating the miR‑15b‑5p/Wnt3A axis Corrigendum in /10.3892/mmr.2022.12912 Retraction in /10.3892/mmr.2024.13399

Zewei Lin, Jikui Liu
Article Number: 318
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Testis-expressed protein 33 is not essential for spermiogenesis and fertility in mice

Mengmeng Xia, Jing Xia, Changmin Niu, Yanan Zhong, Tingting Ge, Yue Ding, Ying Zheng
Article Number: 317
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MicroRNA‑181a promotes epithelial‑mesenchymal transition in esophageal squamous cell carcinoma via the TGF‑β/Smad pathway

Run Xu, Xue-Mei Zhou, Yu-Shan Li, Li Ren, Xin-Rong He
Article Number: 316
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Synergistic effect of the herbal mixture C5E on gemcitabine treatment in PANC‑1 cells

Pyo June Pak, Dong Gun Lee, Ji Hyun Sung, Seung Hyun Jung, Tae-Young Han, Sung Hyo Park, Namhyun Chung
Article Number: 315
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Protective effects of different anti‑inflammatory drugs on tracheal stenosis following injury and potential mechanisms

Zhenjie Huang, Peng Wei, Luoman Gan, Wentao Li, Tonghua Zeng, Caicheng Qin, Zhiyu Chen, Guangnan Liu
Article Number: 314
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Therapeutic effects of quinine in a mouse model of atopic dermatitis

Qian Zhang, Hongjing Jiang, Miao Liu, Xinchen Li, Murong Zhou, Yansi Lyu, Jingkai Huang, Si Chen, Li Wang
Article Number: 313
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miR‑541‑3p inhibits the viability and migration of vascular smooth muscle cells via targeting STIM1

Zhiyu Lv, Dengliang Yi, Chi Zhang, Yujie Xie, He Huang, Zhongcai Fan, Xing Liu
Article Number: 312
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circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis

Yan Wen, Yao Chun, Zhong Qing Lian, Zhang Wei Yong, Yang Mei Lan, Liao Huan, Chen Yi Xi, Li Shu Juan, Zhong Wen Qing, Cheng Jia, Zhang Huan Ji
Article Number: 311
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GASC1 promotes glioma progression by enhancing NOTCH1 signaling

Zhengzheng Xiao, Xiaoli Yang, Zebin Liu, Zheng Shao, Chaojun  Song, Kun Zhang, Xiaobin Wang, Zhengwei Li
Article Number: 310
Published online on: 28 February 2021

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Downregulation of lncRNA RPLP0P2 inhibits cell proliferation, invasion and migration, and promotes apoptosis in colorectal cancer

Hang Yuan, Shiliang Tu, Yingyu Ma, Yueming Sun
Article Number: 309
Published online on: 28 February 2021

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Chidamide induces apoptosis in DLBCL cells by suppressing the HDACs/STAT3/Bcl‑2 pathway

Hongwei Zhang, Fenqing Chi, Keru Qin, Xiuli Mu, Lieyang Wang, Bin  Yang, Yanli Wang, Min Bai, Zhenhua Li, Liping Su, Baofeng Yu
Article Number: 308
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Functions of circular RNAs in bladder, prostate and renal cell cancer (Review)

Longfei Yang, Xiaofeng Zou, Junrong Zou, Guoxi Zhang
Article Number: 307
Published online on: 26 February 2021

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20(s)‑ginseonside‑Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone‑injured C2C12 myotube‑based model of skeletal atrophy in vitro Corrigendum in /10.3892/mmr.2021.12259

Manying Wang, Rui Jiang, Jianzeng Liu, Xiaohao Xu, Guang Sun, Daqing Zhao, Liwei Sun
Article Number: 306
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Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation

He-Ming Huang, Xiao-Ru Zhou, Yan-Jun Liu, Shi-Jie Fan, Li-Ping Liao, Jing Huang, Cui-Cui Shi, Liang Yu, Jin-Jin Pen, Cheng Luo, Yuan-Yuan Zhang, Guang-Ming Li
Article Number: 305
Published online on: 26 February 2021

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MicroRNA‑199a/b‑5p inhibits endometrial cancer cell metastasis and invasion by targeting FAM83B in the epithelial‑to‑mesenchymal transition signaling pathway

Hanzhen Xiong, Na Wang, Hui Chen, Minfen Zhang, Qiongyan Lin
Article Number: 304
Published online on: 26 February 2021

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miR‑875‑5p regulates IR and inflammation via targeting TXNRD1 in gestational diabetes rats

Songbo Fu, Songquan Fu, Xiaoni Ma, Xiaomei Yang, Jizu Ling
Article Number: 303
Published online on: 25 February 2021

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Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
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[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review)

Yuwen Zeng, Yutong Yan, Shiye Wu, Wanshan Wu, Ke Chen, Youyi Lai, Qing Ye, Nan Zhang, Yuanyuan Zhou
Article Number: 320
Published online on: 23 September 2026

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Lactylation in gastric cancer: From mechanisms to clinical applications (Review)

Yuliang Fang, Peng Chen, Yuhong Gao, Yanpiao Li, Xue Li
Article Number: 319
Published online on: 23 September 2026

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Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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