Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
August-2023 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2023 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF

  • Authors:
    • Zhi-Qing Zhu
    • Tian Zhang
    • Shuo Chang
    • Zhen-Hua Ren
    • Qin Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Pediatrics, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China, Department of Anatomy, Anhui Medical University, Hefei, Anhui 230032, P.R. China
    Copyright: © Zhu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 157
    |
    Published online on: June 30, 2023
       https://doi.org/10.3892/mmr.2023.13044
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study aimed to screen for potential biomarkers in the urine of immunoglobulin A vasculitis with nephritis (IgAVN) using parallel accumulation‑serial fragmentation combined with data‑independent acquisition (diaPASEF) proteomic approach. Urine proteomes of eight children with IgAVN and eight healthy children were identified by diaPASEF and all differential proteins were analyzed by Gene Ontology and Kyoto Encyclopedia of Gene and Genome. Then, the specific biomarkers of urine samples from 10 children with IgAVN, 10 children with IgAV and 10 healthy children were verified by ELISA. The present study screened 254 differential proteins from the experiment, including 190 upregulated proteins and 64 downregulated proteins. The results of the ELISA showed that the concentration of urinary zinc‑alpha‑2‑glycoprotein (AZGP1) in children with IgAVN was significantly higher compared with that in children with IgAV and healthy children. The present study provided the potential clinical application of AZGP1 as a helpful biomarker and a potential indicator for early diagnosis of the occurrence of IgAVN.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

View References

1 

Chen J, Fang X, Dang X, Wu X and Yi Z: Association of the paired box 2 gene polymorphism with the susceptibility and pathogenesis of Henoch-Schönlein Purpura in children. Mol Med Rep. 11:1997–2003. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Leung AKC, Barankin B and Leong KF: Henoch-Schönlein Purpura in Children: An updated review. Curr Pediatric Rev. 16:265–276. 2020. View Article : Google Scholar : PubMed/NCBI

3 

Pillebout E and Sunderkotter C: IgA vasculitis. Semin Immunopathol. 43:729–738. 2021. View Article : Google Scholar : PubMed/NCBI

4 

Oni L and Sampath S: Childhood IgA vasculitis (Henoch Schonlein Purpura)-advances and knowledge gaps. Front Pediatr. 7:2572019. View Article : Google Scholar : PubMed/NCBI

5 

Xie B, Zhang W, Zhang Q, Zhang Q, Wang Y, Sun L, Liu M and Zhou P: An integrated transcriptomic and proteomic analysis identifies significant novel pathways for Henoch-Schönlein Purpura nephritis progression. Biomed Res Int. 2020:24891752020. View Article : Google Scholar : PubMed/NCBI

6 

Gao R, Niu X, Zhu L, Qi R and He L: iTRAQ quantitative proteomic analysis differentially expressed proteins and signal pathways in Henoch-Schönlein Purpura nephritis. Am J Transl Res. 12:7908–7922. 2020.PubMed/NCBI

7 

Fang X, Wu H, Lu M, Cao Y, Wang R, Wang M, Gao C and Xia Z: Urinary proteomics of Henoch-Schönlein Purpura nephritis in children using liquid chromatography-tandem mass spectrometry. Clin Proteomics. 17:102020. View Article : Google Scholar : PubMed/NCBI

8 

Naderi AS and Reilly RF: Primary care approach to proteinuria. J Am Board Fam Med. 21:569–574. 2008. View Article : Google Scholar : PubMed/NCBI

9 

Taherkhani A, Farrokhi Yekta R, Mohseni M, Saidijam M and Arefi Oskouie A: Chronic kidney disease: A review of proteomic and metabolomic approaches to membranous glomerulonephritis, focal segmental glomerulosclerosis, and IgA nephropathy biomarkers. Proteome Sci. 17:72019. View Article : Google Scholar : PubMed/NCBI

10 

Li J, Smith LS and Zhu HJ: Data-independent acquisition (DIA): An emerging proteomics technology for analysis of drug-metabolizing enzymes and transporters. Drug discovery today. Technologies. 39:49–56. 2021.PubMed/NCBI

11 

Demichev V, Szyrwiel L, Yu F, Teo GC, Rosenberger G, Niewienda A, Ludwig D, Decker J, Kaspar-Schoenefeld S, Lilley KS, et al: dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts. Nat Commun. 13:39442022. View Article : Google Scholar : PubMed/NCBI

12 

Mun DG, Vanderboom PM, Madugundu AK, Garapati K, Chavan S, Peterson JA, Saraswat M and Pandey A: DIA-based proteome profiling of nasopharyngeal Swabs from COVID-19 patients. J Proteome Res. 20:4165–4175. 2021. View Article : Google Scholar : PubMed/NCBI

13 

Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, Buoncompagni A, Lazar C, Bilge I, Uziel Y, et al: EULAR/PRINTO/PRES criteria for Henoch-Schönlein Purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis. 69:798–806. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Parker SJ, Rost H, Rosenberger G, Collins BC, Malmström L, Amodei D, Venkatraman V, Raedschelders K, Van Eyk JE and Aebersold R: Identification of a set of conserved eukaryotic internal retention time standards for data-independent acquisition mass spectrometry. Mol Cell Proteomics. 14:2800–2813. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Meier F, Brunner AD, Koch S, Koch H, Lubeck M, Krause M, Goedecke N, Decker J, Kosinski T, Park MA, et al: Online parallel accumulation-serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer. Mol Cell Proteomics. 17:2534–2545. 2018. View Article : Google Scholar : PubMed/NCBI

16 

Gotz S, Garcia-Gomez JM, Terol J, Williams TD, Nagaraj SH, Nueda MJ, Robles M, Talón M, Dopazo J and Conesa A: High-throughput functional annotation and data mining with the Blast2GO suite. Nucleic Acids Res. 36:3420–3435. 2008. View Article : Google Scholar : PubMed/NCBI

17 

Kanehisa M, Goto S, Sato Y, Furumichi M and Tanabe M: KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 40:D109–D114. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Szklarczyk D, Franceschini A, Wyder S, Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos A, Tsafou KP, et al: STRING v10: Protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res. 43:D447–D452. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Chen JY and Mao JH: Henoch-Schönlein Purpura nephritis in children: Incidence, pathogenesis and management. World J Pediatr. 11:29–34. 2015. View Article : Google Scholar : PubMed/NCBI

20 

Mucha K, Bakun M, Jazwiec R, Dadlez M, Florczak M, Bajor M, Gala K and Pączek L: Complement components, proteolysisrelated, and cell communicationrelated proteins detected in urine proteomics are associated with IgA nephropathy. Pol Arch Med Wewn. 124:380–386. 2014.PubMed/NCBI

21 

Surin B, Sachon E, Rougier JP, Steverlynck C, Garreau C, Lelongt B, Ronco P and Piedagnel R: LG3 fragment of endorepellin is a possible biomarker of severity in IgA nephropathy. Proteomics. 13:142–152. 2013. View Article : Google Scholar : PubMed/NCBI

22 

Neprasova M, Maixnerova D, Novak J, Reily C, Julian BA, Boron J, Novotny P, Suchanek M, Tesar V and Kacer P: Toward noninvasive diagnosis of IgA nephropathy: A Pilot urinary metabolomic and proteomic study. Dis Markers. 2016:36509092016. View Article : Google Scholar : PubMed/NCBI

23 

Guo Z, Wang Z, Lu C, Yang S, Sun H, Reziw, Guo Y, Sun W and Yue H: Analysis of the differential urinary protein profile in IgA nephropathy patients of Uygur ethnicity. BMC Nephrol. 19:3582018. View Article : Google Scholar : PubMed/NCBI

24 

Rocchetti MT, Papale M, d'Apollo AM, Suriano IV, Di Palma AM, Vocino G, Montemurno E, Varraso L, Grandaliano G, Di Paolo S and Gesualdo L: Association of urinary laminin G-like 3 and free K light chains with disease activity and histological injury in IgA nephropathy. Clin J Am Soc Nephrol. 8:1115–1125. 2013. View Article : Google Scholar : PubMed/NCBI

25 

He Q, Shao L, Yu J, Ji S, Wang H, Mao Y and Chen J: Urinary proteome analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with magnetic beads for identifying the pathologic presentation of clinical early IgA nephropathy. J Biomed Nanotechnol. 8:133–139. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Taylor S, Pieri K, Nanni P, Tica J, Barratt J and Didangelos A: Phosphatidylethanolamine binding protein-4 (PEBP4) is increased in IgA nephropathy and is associated with IgA-positive B-cells in affected kidneys. J Autoimmun. 105:1023092019. View Article : Google Scholar : PubMed/NCBI

27 

Rudnicki M, Siwy J, Wendt R, Lipphardt M, Koziolek MJ, Maixnerova D, Peters B, Kerschbaum J, Leierer J, Neprasova M, et al: Urine proteomics for prediction of disease progression in patients with IgA nephropathy. Nephrol Dial Transplant. 37:42–52. 2021. View Article : Google Scholar : PubMed/NCBI

28 

Ning X, Yin Z, Li Z, Xu J, Wang L, Shen W, Lu Y, Cai G, Zhang X and Chen X: Comparative proteomic analysis of urine and laser microdissected glomeruli in IgA nephropathy. Clin Exp Pharmacol Physiol. 44:576–585. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Turnier JL, Brunner HI, Bennett M, Aleed A, Gulati G, Haffey WD, Thornton S, Wagner M, Devarajan P, Witte D, et al: Discovery of SERPINA3 as a candidate urinary biomarker of lupus nephritis activity. Rheumatology (Oxford). 58:321–330. 2019. View Article : Google Scholar : PubMed/NCBI

30 

Cai Z, Zhang S, Wu P, Ren Q, Wei P, Hong M, Feng Y, Wong CK, Tang H and Zeng H: A novel potential target of IL-35-regulated JAK/STAT signaling pathway in lupus nephritis. Clin Transl Med. 11:e3092021. View Article : Google Scholar : PubMed/NCBI

31 

Varghese SA, Powell TB, Budisavljevic MN, Oates JC, Raymond JR, Almeida JS and Arthur JM: Urine biomarkers predict the cause of glomerular disease. J Am Soc Nephrol. 18:913–922. 2007. View Article : Google Scholar : PubMed/NCBI

32 

He X, Yin W, Ding Y, Cui SJ, Luan J, Zhao P, Yue X, Yu C, Laing X and Zhao Y: Higher serum angiotensinogen is an indicator of IgA vasculitis with nephritis revealed by comparative proteomes analysis. PLoS One. 10:e01305362015. View Article : Google Scholar : PubMed/NCBI

33 

Schmitt R: ZAG-a novel biomarker for cardiovascular risk in ESRD patients? Kidney Int. 94:858–860. 2018. View Article : Google Scholar : PubMed/NCBI

34 

Sörensen-Zender I, Beneke J, Schmidt BM, Menne J, Haller H and Schmitt R: Zinc-alpha2-glycoprotein in patients with acute and chronic kidney disease. BMC Nephrol. 14:1452013. View Article : Google Scholar : PubMed/NCBI

35 

Soggiu A, Piras C, Bonizzi L, Hussein HA, Pisanu S and Roncada P: A discovery-phase urine proteomics investigation in type 1 diabetes. Acta Diabetol. 49:453–464. 2012. View Article : Google Scholar : PubMed/NCBI

36 

Somparn P, Hirankarn N, Leelahavanichkul A, Khovidhunkit W, Thongboonkerd V and Avihingsanon Y: Urinary proteomics revealed prostaglandin H(2)D-isomerase, not Zn-alpha2-glycoprotein, as a biomarker for active lupus nephritis. J Proteomics. 75:3240–3247. 2012. View Article : Google Scholar : PubMed/NCBI

37 

Ekman R, Johansson BG and Ravnskov U: Renal handling of Zn-alpha2-glycoprotein as compared with that of albumin and the retinol-binding protein. J Clin Invest. 57:945–954. 1976. View Article : Google Scholar : PubMed/NCBI

38 

Pelletier CC, Koppe L, Croze ML, Kalbacher E, Vella RE, Guebre-Egziabher F, Géloën A, Badet L, Fouque D and Soulage CO: White adipose tissue overproduces the lipid-mobilizing factor zinc alpha2-glycoprotein in chronic kidney disease. Kidney Int. 83:878–886. 2013. View Article : Google Scholar : PubMed/NCBI

39 

Pelletier CC, Koppe L, Alix PM, Kalbacher E, Croze ML, Hadj-Aissa A, Fouque D, Guebre-Egziabher F and Soulage CO: The relationship between renal function and plasma concentration of the cachectic factor zinc-alpha2-glycoprotein (ZAG) in adult patients with chronic kidney disease. PLoS One. 9:e1034752014. View Article : Google Scholar : PubMed/NCBI

40 

Robson KJ, Ooi JD, Holdsworth SR, Rossjohn J and Kitching AR: HLA and kidney disease: From associations to mechanisms. Nat Rev Nephrol. 14:636–655. 2018. View Article : Google Scholar : PubMed/NCBI

41 

Bouchara A, Yi D, Pastural M, Granjon S, Selag JC, Laville M, Arkouche W, Pelletier S, Fouque D, Soulage CO and Koppe L: Serum levels of the adipokine zinc-alpha2-glycoprotein (ZAG) predict mortality in hemodialysis patients. Kidney Int. 94:983–992. 2018. View Article : Google Scholar : PubMed/NCBI

42 

Matarese G and La Cava A: The intricate interface between immune system and metabolism. Trends Immunol. 25:193–200. 2004. View Article : Google Scholar : PubMed/NCBI

43 

Noh JY, Shin JU, Kim JH, Kim SH, Kim BM, Kim YH, Park S, Kim TG, Shin KO, Park K and Lee KH: ZAG regulates the skin barrier and immunity in atopic dermatitis. J Invest Dermatol. 139:1648–1657. e16472019. View Article : Google Scholar : PubMed/NCBI

44 

Na HS, Kwon JE, Lee SH, Jhun J, Kim SM, Kim SY, Kim EK, Jung K, Park SH and Cho ML: Th17 and IL-17 cause acceleration of inflammation and fat loss by inducing alpha2-glycoprotein 1 (AZGP1) in rheumatoid arthritis with high-fat diet. Am J Pathol. 187:1049–1058. 2017. View Article : Google Scholar : PubMed/NCBI

45 

Yeregui E, Masip J, Viladés C, Domingo P, Pacheco YM, Blanco J, Mallolas J, Alba V, Vargas M, García-Pardo G, et al: Adipokines as new biomarkers of immune recovery: Apelin receptor, RBP4 and ZAG are related to CD4(+) T-cell reconstitution in PLHIV on suppressive antiretroviral therapy. Int J Mol Sci. 23:22022022. View Article : Google Scholar : PubMed/NCBI

46 

Romauch M: Zinc-alpha2-glycoprotein as an inhibitor of amine oxidase copper-containing 3. Open Biol. 10:1900352020. View Article : Google Scholar : PubMed/NCBI

47 

Schmitt R, Marlier A and Cantley LG: Zag expression during aging suppresses proliferation after kidney injury. J Am Soc Nephrol. 19:2375–2383. 2008. View Article : Google Scholar : PubMed/NCBI

48 

Sörensen-Zender I, Bhayana S, Susnik N, Rolli V, Batkai S, Baisantry A, Bahram S, Sen P, Teng B, Lindner R, et al: Zinc-alpha2-Glycoprotein exerts antifibrotic effects in kidney and heart. J Am Soc Nephrol. 26:2659–2668. 2015. View Article : Google Scholar : PubMed/NCBI

49 

do Valle Duraes F, Lafont A, Beibel M, Martin K, Darribat K, Cuttat R, Waldt A, Naumann U, Wieczorek G, Gaulis S, et al: Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis. JCI Insight. 5:e1306512020. View Article : Google Scholar : PubMed/NCBI

50 

Adams EJ and Luoma AM: The adaptable major histocompatibility complex (MHC) fold: Structure and function of nonclassical and MHC class I-like molecules. Annu Rev Immunol. 31:529–561. 2013. View Article : Google Scholar : PubMed/NCBI

51 

Takagaki M, Honke K, Tsukamoto T, Higashiyama S, Taniguchi N, Makita A and Ohkubo I: Zn-alpha 2-glycoprotein is a novel adhesive protein. Biochem Biophys Res Commun. 201:1339–1347. 1994. View Article : Google Scholar : PubMed/NCBI

52 

Song Y, Huang X, Yu G, Qiao J, Cheng J, Wu J and Chen J: Pathogenesis of IgA Vasculitis: An Up-to-date review. Front Immunol. 12:7716192021. View Article : Google Scholar : PubMed/NCBI

53 

Chimenti MS, Ballanti E, Triggianese P and Perricone R: Vasculitides and the complement system: A comprehensive review. Clin Rev Allergy Immunol. 49:333–346. 2015. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhu Z, Zhang T, Chang S, Ren Z and Zhang Q: AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF. Mol Med Rep 28: 157, 2023.
APA
Zhu, Z., Zhang, T., Chang, S., Ren, Z., & Zhang, Q. (2023). AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF. Molecular Medicine Reports, 28, 157. https://doi.org/10.3892/mmr.2023.13044
MLA
Zhu, Z., Zhang, T., Chang, S., Ren, Z., Zhang, Q."AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF". Molecular Medicine Reports 28.2 (2023): 157.
Chicago
Zhu, Z., Zhang, T., Chang, S., Ren, Z., Zhang, Q."AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF". Molecular Medicine Reports 28, no. 2 (2023): 157. https://doi.org/10.3892/mmr.2023.13044
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu Z, Zhang T, Chang S, Ren Z and Zhang Q: AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF. Mol Med Rep 28: 157, 2023.
APA
Zhu, Z., Zhang, T., Chang, S., Ren, Z., & Zhang, Q. (2023). AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF. Molecular Medicine Reports, 28, 157. https://doi.org/10.3892/mmr.2023.13044
MLA
Zhu, Z., Zhang, T., Chang, S., Ren, Z., Zhang, Q."AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF". Molecular Medicine Reports 28.2 (2023): 157.
Chicago
Zhu, Z., Zhang, T., Chang, S., Ren, Z., Zhang, Q."AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF". Molecular Medicine Reports 28, no. 2 (2023): 157. https://doi.org/10.3892/mmr.2023.13044
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team