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Article

Quercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review

  • Authors:
    • Paula A. Oliveira
    • Beatriz Medeiros-Fonseca
    • Carmen Vasconcelos-Nóbrega
    • Antonieta Alvarado
    • Maria João Pires
    • Helena Vala
    • Ana I.R.N.A. Barros
    • Ana I. Faustino-Rocha
  • View Affiliations / Copyright

    Affiliations: Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences (ECAV), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal, Centre for Τhe Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Inov4Agro, 5000-801 Vila Real, Portugal, Centre for The Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Inov4Agro, 5000-801 Vila Real, Portugal
  • Article Number: 175
    |
    Published online on: July 31, 2023
       https://doi.org/10.3892/mmr.2023.13062
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Abstract

Acorns have traditionally been used in the human diet and for the treatment of specific diseases. Therefore, the present study performed a systematic review of studies which investigated the effects of Quercus spp. extracts in cancer prevention and treatment. A systematic literature search was performed for original records which addressed the anticancer effects of Quercus spp. extract in in vitro and in vivo cancer models. Body composition, food consumption, tumor development and/or toxicity were evaluated in in vivo studies, while cytotoxicity was evaluated in in vitro studies. Few studies and low sample sizes presented a challenge in the drawing of solid conclusions. Overall, the results suggested a positive impact of Quercus spp. extract, by reducing cancer development. Therefore, more studies with different cancer cell lines and animal models to address the efficacy of the acorn extracts in several types of cancer are required. Furthermore, the effects of acorn flour, incorporated in the diet, in an animal model of mammary cancer should be evaluated.
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Copy and paste a formatted citation
Spandidos Publications style
Oliveira PA, Medeiros-Fonseca B, Vasconcelos-Nóbrega C, Alvarado A, Pires MJ, Vala H, Barros AI and Faustino-Rocha AI: <em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review. Mol Med Rep 28: 175, 2023.
APA
Oliveira, P.A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M.J., Vala, H. ... Faustino-Rocha, A.I. (2023). <em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review. Molecular Medicine Reports, 28, 175. https://doi.org/10.3892/mmr.2023.13062
MLA
Oliveira, P. A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M. J., Vala, H., Barros, A. I., Faustino-Rocha, A. I."<em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review". Molecular Medicine Reports 28.3 (2023): 175.
Chicago
Oliveira, P. A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M. J., Vala, H., Barros, A. I., Faustino-Rocha, A. I."<em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review". Molecular Medicine Reports 28, no. 3 (2023): 175. https://doi.org/10.3892/mmr.2023.13062
Copy and paste a formatted citation
x
Spandidos Publications style
Oliveira PA, Medeiros-Fonseca B, Vasconcelos-Nóbrega C, Alvarado A, Pires MJ, Vala H, Barros AI and Faustino-Rocha AI: <em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review. Mol Med Rep 28: 175, 2023.
APA
Oliveira, P.A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M.J., Vala, H. ... Faustino-Rocha, A.I. (2023). <em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review. Molecular Medicine Reports, 28, 175. https://doi.org/10.3892/mmr.2023.13062
MLA
Oliveira, P. A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M. J., Vala, H., Barros, A. I., Faustino-Rocha, A. I."<em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review". Molecular Medicine Reports 28.3 (2023): 175.
Chicago
Oliveira, P. A., Medeiros-Fonseca, B., Vasconcelos-Nóbrega, C., Alvarado, A., Pires, M. J., Vala, H., Barros, A. I., Faustino-Rocha, A. I."<em>Quercus</em> spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review". Molecular Medicine Reports 28, no. 3 (2023): 175. https://doi.org/10.3892/mmr.2023.13062
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