|
1
|
Wang W, Jiang B, Sun H, Ru X, Sun D, Wang
L, Wang L, Jiang Y, Li Y, Wang Y, et al: Prevalence, incidence, and
mortality of stroke in China: Results from a nationwide
population-based survey of 480 687 adults. Circulation.
135:759–771. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wang D, Liu J, Liu M, Lu C, Brainin M and
Zhang J: Patterns of stroke between university hospitals and
nonuniversity hospitals in Mainland China: Prospective multicenter
hospital-based registry study. World Neurosurg. 98:258–265. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Yuan Y, Tian Y, Jiang H, Cai LY, Song J,
Peng R and Zhang XM: Mechanism of PGC-1α-mediated mitochondrial
biogenesis in cerebral ischemia-reperfusion injury. Front Mol
Neurosci. 16:12249642023. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Uzdensky AB: Apoptosis regulation in the
penumbra after ischemic stroke: Expression of pro- and
antiapoptotic proteins. Apoptosis. 24:687–702. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chao XD, Fei F and Fei Z: The role of
excitatory amino acid transporters in cerebral ischemia. Neurochem
Res. 35:1224–1230. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Chi OZ, Hunter C, Liu X and Weiss HR:
Effects of exogenous excitatory amino acid neurotransmitters on
blood-brain barrier disruption in focal cerebral ischemia.
Neurochem Res. 34:1249–1254. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Takahashi K, Foster JB and Lin CL:
Glutamate transporter EAAT2: Regulation, function, and potential as
a therapeutic target for neurological and psychiatric disease. Cell
Mol Life Sci. 72:3489–3506. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Sankhala KK, Mita MM, Mita AC and Takimoto
CH: Heat shock proteins: A potential anticancer target. Curr Drug
Targets. 12:2001–2008. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Whitesell L and Lindquist SL: HSP90 and
the chaperoning of cancer. Nat Rev Cancer. 5:761–772. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Grad I, Cederroth CR, Walicki J, Grey C,
Barluenga S, Winssinger N, De Massy B, Nef S and Picard D: The
molecular chaperone Hsp90α is required for meiotic progression of
spermatocytes beyond pachytene in the mouse. PLoS One.
5:e157702010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zhang R, Liu C, Ji Y, Teng L and Guo Y:
Neuregulin-1β plays a neuroprotective role by inhibiting the Cdk5
signaling pathway after cerebral ischemia-reperfusion injury in
rats. J Mol Neurosci. 66:261–272. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Longa EZ, Weinstein PR, Carlson S and
Cummins R: Reversible middle cerebral artery occlusion without
craniectomy in rats. Stroke. 20:84–91. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yu X, Luo Y, Yang L, Chen P and Duan X:
P-hydroxybenzyl alcohol ameliorates neuronal cerebral
ischemia-reperfusion injury by activating mitochondrial autophagy
through SIRT1. Mol Med Rep. 27:682023. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhou M, Wang H, Zeng X, Yin P, Zhu J, Chen
W, Li X, Wang L, Wang L, Liu Y, et al: Mortality, morbidity, and
risk factors in China and its provinces, 1990–2017: A systematic
analysis for the global burden of disease study 2017. Lancet.
394:1145–1158. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
GBD 2017 Causes of Death Collaborators, .
Global, regional, and national age-sex-specific mortality for 282
causes of death in 195 countries and territories, 1980–2017: A
systematic analysis for the global burden of disease study 2017.
Lancet. 392:1736–1788. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bradley E, Zhao X, Wang R, Brann D,
Bieberich E and Wang G: Low dose Hsp90 inhibitor 17AAG protects
neural progenitor cells from ischemia induced death. J Cell Commun
Signal. 8:353–362. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chinese Society of Neurology and Chinese
Stroke Society, . Chinese guidelines for diagnosis and treatment of
acute ischemic stroke 2018. Chin J Neurol. 9:666–682. 2018.
|
|
18
|
Adelson JD, Barreto GE, Xu L, Kim T, Brott
BK, Ouyang YB, Naserke T, Djurisic M, Xiong X, Shatz CJ and Giffard
RG: Neuroprotection from stroke in the absence of MHCI or PirB.
Neuron. 73:1100–1107. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Pundik S, Xu K and Sundararajan S:
Reperfusion brain injury: Focus on cellular bioenergetics.
Neurology. 79 (13 Suppl 1):S44–S51. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhang Z, Yan J, Taheri S, Liu KJ and Shi H
and Shi H: Hypoxia-inducible factor 1 contributes to
N-acetylcysteine's protection in stroke. Free Radic Biol Med.
68:8–21. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wen XR, Li C, Zong YY, Yu CZ, Xu J, Han D
and Zhang GY: Dual inhibitory roles of geldanamycin on the c-Jun
NH2-terminal kinase 3 signal pathway through suppressing the
expression of mixed-lineage kinase 3 and attenuating the activation
of apoptosis signal-regulating kinase 1 via facilitating the
activation of Akt in ischemic brain injury. Neuroscience.
156:483–497. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Qi J, Liu Y, Yang P, Chen T, Liu XZ, Yin
Y, Zhang J and Wang F: Heat shock protein 90 inhibition by
17-dimethylaminoethylamino-17-demethoxygeldanamycin protects
blood-brain barrier integrity in cerebral ischemic stroke. Am J
Transl Res. 7:1826–1837. 2015.PubMed/NCBI
|
|
23
|
Qi J, Han X, Liu HT, Chen T, Zhang JL,
Yang P, Bo SH, Lu XT and Zhang J:
17-Dimethylaminoethylamino-17-demethoxygel-danamycin attenuates
inflammatory responses in experimental stroke. Biol Pharm Bull.
37:1713–1718. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Voss AK, Thomas T and Gruss P: Mice
lacking HSP90beta fail to develop a placental labyrinth.
Development. 127:1–11. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pajarillo E, Rizor A, Lee J, Aschner M and
Lee E: The role of astrocytic glutamate transporters GLT-1 and
GLAST in neurological disorders: Potential targets for
neurotherapeutics. Neuropharmacology. 161:1075592019. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mahmoud S, Gharagozloo M, Simard C and
Gris D: Astrocytes maintain glutamate homeostasis in the CNS by
controlling the balance between glutamate uptake and release.
Cells. 8:1842019. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wang H, Li J, Zhang H, Wang M, Xiao L,
Wang Y and Cheng Q: Regulation of microglia polarization after
cerebral ischemia. Front Cell Neurosci. 17:11826212023. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Leung SW, Lai JH, Wu JC, Tsai YR, Chen YH,
Kang SJ, Chiang YH, Chang CF and Chen KY: Neuroprotective effects
of emodin against ischemia/reperfusion injury through activating
ERK-1/2 signaling pathway. Int J Mol Sci. 21:28992020. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Peng M, Ling X, Song R, Gao X, Liang Z,
Fang F and Cang J: Upregulation of GLT-1 via PI3K/Akt pathway
contributes to neuroprotection induced by dexmedetomidine. Front
Neurol. 10:10412019. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bacigaluppi M, Russo GL,
Peruzzotti-Jametti L, Rossi S, Sandrone S, Butti E, De Ceglia R,
Bergamaschi A, Motta C, Gallizioli M, et al: Neural stem cell
transplantation induces stroke recovery by upregulating glutamate
transporter GLT-1 in astrocytes. J Neurosci. 36:10529–10544. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Krzyżanowska W, Pomierny B, Bystrowska B,
Pomierny-Chamioło L, Filip M, Budziszewska B and Pera J:
Ceftriaxone- and N-acetylcysteine-induced brain tolerance to
ischemia: Influence on glutamate levels in focal cerebral ischemia.
PLoS One. 12:e01862432017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Sha L, Wang X, Li J, Shi X, Wu L, Shen Y
and Xu Q: Pharmacologic inhibition of Hsp90 to prevent GLT-1
degradation as an effective therapy for epilepsy. J Exp Med.
214:547–563. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Peng YC, Wang S, Zhang Y, Huang LJ, Wang
XL and Peng Y: Hsp90β inhibitors prevent GLT-1 degradation but have
no beneficial efficacy on absence epilepsy. J Asian Nat Prod Res.
21:905–915. 2019. View Article : Google Scholar : PubMed/NCBI
|
