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Association of gut dysbiosis with first‑episode psychosis (Review)

  • Authors:
    • Christos Theleritis
    • Maria-Ioanna Stefanou
    • Marina Demetriou
    • Evangelos Alevyzakis
    • Konstantinos Triantafyllou
    • Nikolaos Smyrnis
    • Demetrios A. Spandidos
    • Emmanouil Rizos
  • View Affiliations / Copyright

    Affiliations: Second Department of Psychiatry, Attikon University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece, Second Department of Neurology, School of Medicine, Attikon University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece, Hepatogastroenterology Unit, Second Department of Propaedeutic Internal Medicine, Attikon University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece, Laboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece
    Copyright: © Theleritis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 130
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    Published online on: May 24, 2024
       https://doi.org/10.3892/mmr.2024.13254
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Abstract

The gut‑microbiota‑brain axis is a complex bidirectional communication system linking the gastrointestinal tract to the brain. Changes in the balance, composition and diversity of the gut‑microbiota (gut dysbiosis) have been found to be associated with the development of psychosis. Early‑life stress, along with various stressors encountered in different developmental phases, have been shown to be associated with the abnormal composition of the gut microbiota, leading to irregular immunological and neuroendocrine functions, which are potentially responsible for the occurrence of first‑episode psychosis (FEP). The aim of the present narrative review was to summarize the significant differences of the altered microbiome composition in patients suffering from FEP vs. healthy controls, and to discuss its effects on the occurrence and intensity of symptoms in FEP.
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Copy and paste a formatted citation
Spandidos Publications style
Theleritis C, Stefanou M, Demetriou M, Alevyzakis E, Triantafyllou K, Smyrnis N, Spandidos DA and Rizos E: Association of gut dysbiosis with first‑episode psychosis (Review). Mol Med Rep 30: 130, 2024.
APA
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N. ... Rizos, E. (2024). Association of gut dysbiosis with first‑episode psychosis (Review). Molecular Medicine Reports, 30, 130. https://doi.org/10.3892/mmr.2024.13254
MLA
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N., Spandidos, D. A., Rizos, E."Association of gut dysbiosis with first‑episode psychosis (Review)". Molecular Medicine Reports 30.1 (2024): 130.
Chicago
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N., Spandidos, D. A., Rizos, E."Association of gut dysbiosis with first‑episode psychosis (Review)". Molecular Medicine Reports 30, no. 1 (2024): 130. https://doi.org/10.3892/mmr.2024.13254
Copy and paste a formatted citation
x
Spandidos Publications style
Theleritis C, Stefanou M, Demetriou M, Alevyzakis E, Triantafyllou K, Smyrnis N, Spandidos DA and Rizos E: Association of gut dysbiosis with first‑episode psychosis (Review). Mol Med Rep 30: 130, 2024.
APA
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N. ... Rizos, E. (2024). Association of gut dysbiosis with first‑episode psychosis (Review). Molecular Medicine Reports, 30, 130. https://doi.org/10.3892/mmr.2024.13254
MLA
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N., Spandidos, D. A., Rizos, E."Association of gut dysbiosis with first‑episode psychosis (Review)". Molecular Medicine Reports 30.1 (2024): 130.
Chicago
Theleritis, C., Stefanou, M., Demetriou, M., Alevyzakis, E., Triantafyllou, K., Smyrnis, N., Spandidos, D. A., Rizos, E."Association of gut dysbiosis with first‑episode psychosis (Review)". Molecular Medicine Reports 30, no. 1 (2024): 130. https://doi.org/10.3892/mmr.2024.13254
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