|
1
|
Green S, Walter P, Kumar V, Krust A,
Bornert JM, Argos P and Chambon P: Human oestrogen receptor cDNA:
Sequence, expression and homology to v-erb-A. Nature. 320:134–139.
1986. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Jameson L, De Groot LJ, de Kretser DM,
Giudice LC, Grossman AB, Melmed S, Potts JT and Weir GC:
Endocrinology: Adult and Pediatric. 7th edition. W.B Saunders;
Philadelphia, PH: pp. 2200–2350. 2016
|
|
3
|
Fuentes N and Silveyra P: Estrogen
receptor signaling mechanisms. Adv Protein Chem Struct Biol.
116:135–170. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Faltas CL, LeBron KA and Holz MK:
Unconventional estrogen signaling in health and disease.
Endocrinology. 161:bqaa0302020. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hazell GG, Yao ST, Roper JA, Prossnitz ER,
O'Carroll AM and Lolait SJ: Localisation of GPR30, a novel G
protein-coupled oestrogen receptor, suggests multiple functions in
rodent brain and peripheral tissues. J Endocrinol. 202:223–236.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Arterburn JB and Prossnitz ER: G
Protein-Coupled Estrogen Receptor GPER: Molecular pharmacology and
therapeutic applications. Annu Rev Pharmacol Toxicol. 63:295–320.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Björnström L and Sjöberg M: Mechanisms of
estrogen receptor signaling: Convergence of genomic and nongenomic
actions on target genes. Mol Endocrinol. 19:833–842. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Williams C, Edvardsson K, Lewandowski SA,
Ström A and Gustafsson JA: A genome-wide study of the repressive
effects of estrogen receptor beta on estrogen receptor alpha
signaling in breast cancer cells. Oncogene. 27:1019–1032. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Klinge CM, Jernigan SC, Smith SL,
Tyulmenkov VV and Kulakosky PC: Estrogen response element sequence
impacts the conformation and transcriptional activity of estrogen
receptor alpha. Mol Cell Endocrinol. 174:151–166. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Clusan L, Ferrière F, Flouriot G and
Pakdel F: A basic review on estrogen receptor signaling pathways in
breast cancer. Int J Mol Sci. 24:68342023. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bord S, Horner A, Beavan S and Compston J:
Estrogen receptors alpha and beta are differentially expressed in
developing human bone. J Clin Endocrinol Metab. 86:2309–2314. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gosden JR, Middleton PG and Rout D:
Localization of the human oestrogen receptor gene to chromosome
6q24-q27 by in situ hybridization. Cytogenet Cell Genet.
43:218–220. 1986. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Enmark E, Pelto-Huikko M, Grandien K,
Lagercrantz S, Lagercrantz J, Fried G, Nordenskjöld M and
Gustafsson JA: Human estrogen receptor beta-gene structure,
chromosomal localization and expression pattern. J Clin Endocrinol
Metab. 82:4258–4265. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kumar R, Zakharov MN, Khan SH, Miki R,
Jang H, Toraldo G, Singh R, Bhasin S and Jasuja R: The dynamic
structure of the estrogen receptor. J Amino Acids. 2011:8125402011.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hewitt SC and Korach KS: Estrogen
receptors: Structure, mechanisms and function. Rev Endocr Metab
Disord. 3:193–200. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Barton M, Filardo EJ, Lolait SJ, Thomas P,
Maggiolini M and Prossnitz ER: Twenty years of the G
protein-coupled estrogen receptor GPER: Historical and personal
perspectives. J Steroid Biochem Mol Biol. 176:4–15. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Saito K and Cui H: Estrogen receptor alpha
splice variants, post-translational modifications and their
physiological functions. Cells. 12:8952023. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Flouriot G, Brand H, Denger S, Metivier R,
Kos M, Reid G, Sonntag-Buck V and Gannon F: Identification of a new
isoform of the human estrogen receptor-alpha (hER-alpha) that is
encoded by distinct transcripts and that is able to repress
hER-alpha activation function 1. EMBO J. 19:4688–4700. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wang Z, Zhang X, Shen P, Loggie BW, Chang
Y and Deuel TF: Identification, cloning and expression of human
estrogen receptor-alpha36, a novel variant of human estrogen
receptor-alpha66. Biochem Biophys Res Commun. 336:1023–1027. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Warner M, Fan X, Strom A, Wu W and
Gustafsson JÅ: 25 years of ERβ: A personal journey. J Mol
Endocrinol. 68:R1–R9. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Monteiro FL, Stepanauskaite L, Archer A
and Williams C: Estrogen receptor beta expression and role in
cancers. J Steroid Biochem Mol Biol. 242:1065262024. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Jia M, Dahlman-Wright K and Gustafsson JÅ:
Estrogen receptor alpha and beta in health and disease. Best Pract
Res Clin Endocrinol Metab. 29:557–568. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Arao Y and Korach KS: The physiological
role of estrogen receptor functional domains. Essays Biochem.
65:867–875. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Stender JD, Kim K, Charn TH, Komm B, Chang
KC, Kraus WL, Benner C, Glass CK and Katzenellenbogen BS:
Genome-wide analysis of estrogen receptor alpha DNA binding and
tethering mechanisms identifies Runx1 as a novel tethering factor
in receptor-mediated transcriptional activation. Mol Cell Biol.
30:3943–3955. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Song RX, Zhang Z and Santen RJ: Estrogen
rapid action via protein complex formation involving ERalpha and
Src. Trends Endocrinol Metab. 16:347–353. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Kelly MJ and Levin ER: Rapid actions of
plasma membrane estrogen receptors. Trends Endocrinol Metab.
12:152–156. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Castoria G, Migliaccio A, Bilancio A, Di
Domenico M, de Falco A, Lombardi M, Fiorentino R, Varricchio L,
Barone MV and Auricchio F: PI3-kinase in concert with Src promotes
the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J.
20:6050–6059. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Pedram A, Razandi M, Aitkenhead M, Hughes
CC and Levin ER: Integration of the non-genomic and genomic actions
of estrogen. Membrane-initiated signaling by steroid to
transcription and cell biology. J Biol Chem. 277:50768–50775. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Delmas PD: Treatment of postmenopausal
osteoporosis. Lancet. 359:2018–2026. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lindberg MK, Erlandsson M, Alatalo SL,
Windahl S, Andersson G, Halleen JM, Carlsten H, Gustafsson JA and
Ohlsson C: Estrogen receptor alpha, but not estrogen receptor beta,
is involved in the regulation of the OPG/RANKL
(osteoprotegerin/receptor activator of NF-kappa B ligand) ratio and
serum interleukin-6 in male mice. J Endocrinol. 171:425–433. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Nakamura T, Imai Y, Matsumoto T, Sato S,
Takeuchi K, Igarashi K, Harada Y, Azuma Y, Krust A, Yamamoto Y, et
al: Estrogen prevents bone loss via estrogen receptor alpha and
induction of Fas ligand in osteoclasts. Cell. 130:811–823. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Börjesson AE, Windahl SH, Karimian E,
Eriksson EE, Lagerquist MK, Engdahl C, Antal MC, Krust A, Chambon
P, Sävendahl L and Ohlsson C: The role of estrogen receptor-α and
its activation function-1 for growth plate closure in female mice.
Am J Physiol Endocrinol Metab. 302:E1381–E1389. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Martin-Millan M, Almeida M, Ambrogini E,
Han L, Zhao H, Weinstein RS, Jilka RL, O'Brien CA and Manolagas SC:
The estrogen receptor-alpha in osteoclasts mediates the protective
effects of estrogens on cancellous but not cortical bone. Mol
Endocrinol. 24:323–334. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Manolagas SC, O'Brien CA and Almeida M:
The role of estrogen and androgen receptors in bone health and
disease. Nat Rev Endocrinol. 9:699–712. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Almeida M, Han L, Martin-Millan M, O'Brien
CA and Manolagas SC: Oxidative stress antagonizes Wnt signaling in
osteoblast precursors by diverting beta-catenin from T cell factor-
to forkhead box O-mediated transcription. J Biol Chem.
282:27298–27305. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Smith EP, Boyd J, Frank GR, Takahashi H,
Cohen RM, Specker B, Williams TC, Lubahn DB and Korach KS: Estrogen
resistance caused by a mutation in the estrogen-receptor gene in a
man. N Engl J Med. 331:1056–1061. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Rochira V and Carani C: Aromatase
deficiency in men: A clinical perspective. Nat Rev Endocrinol.
5:559–568. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Morishima A, Grumbach MM, Simpson ER,
Fisher C and Qin K: Aromatase deficiency in male and female
siblings caused by a novel mutation and the physiological role of
estrogens. J Clin Endocrinol Metab. 80:3689–3698. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Conte FA, Grumbach MM, Ito Y, Fisher CR
and Simpson ER: A syndrome of female pseudohermaphrodism,
hypergonadotropic hypogonadism and multicystic ovaries associated
with missense mutations in the gene encoding aromatase (P450arom).
J Clin Endocrinol Metab. 78:1287–1292. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chen GG, Zeng Q and Tse GM: Estrogen and
its receptors in cancer. Med Res Rev. 28:954–974. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chan KKL, Siu MKY, Jiang YX, Wang JJ, Wang
Y, Leung THY, Liu SS, Cheung ANY and Ngan HYS: Differential
expression of estrogen receptor subtypes and variants in ovarian
cancer: Effects on cell invasion, proliferation and prognosis. BMC
Cancer. 17:6062017. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Ciucci A, Zannoni GF, Travaglia D,
Petrillo M, Scambia G and Gallo D: Prognostic significance of the
estrogen receptor beta (ERβ) isoforms ERβ1, ERβ2 and ERβ5 in
advanced serous ovarian cancer. Gynecol Oncol. 132:351–359. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Ignatov T, Modl S, Thulig M, Weißenborn C,
Treeck O, Ortmann O, Zenclussen A, Costa SD, Kalinski T and Ignatov
A: GPER-1 acts as a tumor suppressor in ovarian cancer. J Ovarian
Res. 6:512013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Smith HO, Arias-Pulido H, Kuo DY, Howard
T, Qualls CR, Lee SJ, Verschraegen CF, Hathaway HJ, Joste NE and
Prossnitz ER: GPR30 predicts poor survival for ovarian cancer.
Gynecol Oncol. 114:465–471. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ramírez-de-Arellano A, Pereira-Suárez AL,
Rico-Fuentes C, López-Pulido EI, Villegas-Pineda JC and Sierra-Diaz
E: Distribution and effects of estrogen receptors in prostate
cancer: Associated molecular mechanisms. Front Endocrinol
(Lausanne). 12:8115782022. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Bonkhoff H: Estrogen receptor signaling in
prostate cancer: Implications for carcinogenesis and tumor
progression. Prostate. 78:2–10. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ryu WS, Kim JH, Jang YJ, Park SS, Um JW,
Park SH, Kim SJ, Mok YJ and Kim CS: Expression of estrogen
receptors in gastric cancer and their clinical significance. J Surg
Oncol. 106:456–461. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Deng H, Huang X, Fan J, Wang L, Xia Q,
Yang X, Wang Z and Liu L: A variant of estrogen receptor-alpha,
ER-alpha36 is expressed in human gastric cancer and is highly
correlated with lymph node metastasis. Oncol Rep. 24:171–176.
2010.PubMed/NCBI
|
|
49
|
Xu CY, Guo JL, Jiang ZN, Xie SD, Shen JG,
Shen JY and Wang LB: Prognostic role of estrogen receptor alpha and
estrogen receptor beta in gastric cancer. Ann Surg Oncol.
17:2503–2509. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Jacenik D and Krajewska WM: Significance
of G protein-coupled estrogen receptor in the pathophysiology of
irritable bowel syndrome, inflammatory bowel diseases and
colorectal cancer. Front Endocrinol (Lausanne). 11:3902020.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Baldissera VD, Alves AF, Almeida S,
Porawski M and Giovenardi M: Hepatocellular carcinoma and estrogen
receptors: Polymorphisms and isoforms relations and implications.
Med Hypotheses. 86:67–70. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Wei T, Chen W, Wen L, Zhang J, Zhang Q,
Yang J, Liu H, Chen BW, Zhou Y, Feng X, et al: G protein-coupled
estrogen receptor deficiency accelerates liver tumorigenesis by
enhancing inflammation and fibrosis. Cancer Lett. 382:195–202.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Gupta VK, Banerjee S and Saluja AK:
Learning from gender disparity: Role of estrogen receptor
activation in coping with pancreatic cancer. Cell Mol Gastroenterol
Hepatol. 10:862–863. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Dika E, Patrizi A, Lambertini M,
Manuelpillai N, Fiorentino M, Altimari A, Ferracin M, Lauriola M,
Fabbri E, Campione E, et al: Estrogen receptors and melanoma: A
review. Cells. 8:14632019. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
He M, Yu W, Chang C, Miyamoto H, Liu X,
Jiang K and Yeh S: Estrogen receptor α promotes lung cancer cell
invasion via increase of and cross-talk with infiltrated
macrophages through the CCL2/CCR2/MMP9 and CXCL12/CXCR4 signaling
pathways. Mol Oncol. 14:1779–1799. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Liu S, Hu C, Li M, An J, Zhou W, Guo J and
Xiao Y: Estrogen receptor beta promotes lung cancer invasion via
increasing CXCR4 expression. Cell Death Dis. 13:702022. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Liu C, Liao Y, Fan S, Tang H, Jiang Z,
Zhou B, Xiong J, Zhou S, Zou M and Wang J: G protein-coupled
estrogen receptor (GPER) mediates NSCLC progression induced by
17β-estradiol (E2) and selective agonist G1. Med Oncol. 32:1042015.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Heer E, Harper A, Escandor N, Sung H,
McCormack V and Fidler-Benaoudia MM: Global burden and trends in
premenopausal and postmenopausal breast cancer: A population-based
study. Lancet Glob Health. 8:e1027–e1037. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Cserni G: Histological type and typing of
breast carcinomas and the WHO classification changes over time.
Pathologica. 112:25–41. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Chen P, Li B and Ou-Yang L: Role of
estrogen receptors in health and disease. Front Endocrinol
(Lausanne). 13:8390052022. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Huang B, Omoto Y, Iwase H, Yamashita H,
Toyama T, Coombes RC, Filipovic A, Warner M and Gustafsson JÅ:
Differential expression of estrogen receptor α, β1 and β2 in
lobular and ductal breast cancer. Proc Natl Acad Sci USA.
111:1933–1938. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Beral V; Million Women Study
Collaborators, : Breast cancer and hormone-replacement therapy in
the Million Women Study. Lancet. 362:419–427. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Salagame U, Canfell K and Banks E: An
epidemiological overview of the relationship between hormone
replacement therapy and breast cancer. Expert Rev Endocrinol Metab.
6:397–409. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Meng YG, Han WD, Zhao YL, Huang K, Si YL,
Wu ZQ and Mu YM: Induction of the LRP16 gene by estrogen promotes
the invasive growth of Ishikawa human endometrial cancer cells
through the downregulation of E-cadherin. Cell Res. 17:869–880.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Xu X, Zhang M, Xu F and Jiang S: Wnt
signaling in breast cancer: Biological mechanisms, challenges and
opportunities. Mol Cancer. 19:1652020. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Anbalagan M and Rowan BG: Estrogen
receptor alpha phosphorylation and its functional impact in human
breast cancer. Mol Cell Endocrinol. 418:Pt 3:264–272. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Tsai EM, Wang SC, Lee JN and Hung MC: Akt
activation by estrogen in estrogen receptor-negative breast cancer
cells. Cancer Res. 61:8390–8392. 2001.PubMed/NCBI
|
|
68
|
Dustin D, Gu G and Fuqua SAW: ESR1
mutations in breast cancer. Cancer. 125:3714–3728. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Toy W, Weir H, Razavi P, Lawson M,
Goeppert AU, Mazzola AM, Smith A, Wilson J, Morrow C, Wong WL, et
al: Activating ESR1 mutations differentially affect the efficacy of
ER antagonists. Cancer Discov. 7:277–287. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Klinge CM, Riggs KA, Wickramasinghe NS,
Emberts CG, McConda DB, Barry PN and Magnusen JE: Estrogen receptor
alpha 46 is reduced in tamoxifen resistant breast cancer cells and
re-expression inhibits cell proliferation and estrogen receptor
alpha 66-regulated target gene transcription. Mol Cell Endocrinol.
323:268–276. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Wang ZY and Yin L: Estrogen receptor
alpha-36 (ER-α36): A new player in human breast cancer. Mol Cell
Endocrinol. 418:Pt 3:193–206. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Giacinti L, Claudio PP, Lopez M and
Giordano A: Epigenetic information and estrogen receptor alpha
expression in breast cancer. Oncologist. 11:1–8. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Zhao C, Matthews J, Tujague M, Wan J,
Ström A, Toresson G, Lam EW, Cheng G, Gustafsson JA and
Dahlman-Wright K: Estrogen receptor beta2 negatively regulates the
transactivation of estrogen receptor alpha in human breast cancer
cells. Cancer Res. 67:3955–3962. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Hopp TA, Weiss HL, Parra IS, Cui Y,
Osborne CK and Fuqua SA: Low levels of estrogen receptor b protein
predict resistance to tamoxifen therapy in breast cancer. Clin
Cancer Res. 10:7490–7499. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Markey GC, Cullen R, Diggin P, Hill AD, Mc
Dermott EW, O'Higgins NJ and Duffy MJ: Estrogen receptor-beta mRNA
is associated with adverse outcome in patients with breast cancer.
Tumour Biol. 30:171–175. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Esslimani-Sahla M, Simony-Lafontaine J,
Kramar A, Lavaill R, Mollevi C, Warner M, Gustafsson JA and
Rochefort H: Estrogen receptor beta (ER beta) level but not its ER
beta cx variant helps to predict tamoxifen resistance in breast
cancer. Clin Cancer Res. 10:5769–5776. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Shaaban AM, Green AR, Karthik S, Alizadeh
Y, Hughes TA, Harkins L, Ellis IO, Robertson JF, Paish EC, Saunders
PT, et al: Nuclear and cytoplasmic expression of ERbeta1, ERbeta2
and ERbeta5 identifies distinct prognostic outcome for breast
cancer patients. Clin Cancer Res. 14:5228–5235. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Lee MT, Ho SM, Tarapore P, Chung I and
Leung YK: Estrogen receptor β isoform 5 confers sensitivity of
breast cancer cell lines to chemotherapeutic agent-induced
apoptosis through interaction with Bcl2L12. Neoplasia.
15:1262–1271. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Ignatov T, Weißenborn C, Poehlmann A,
Lemke A, Semczuk A, Roessner A, Costa SD, Kalinski T and Ignatov A:
GPER-1 expression decreases during breast cancer tumorigenesis.
Cancer Invest. 31:309–315. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Fan X, Xu H, Warner M and Gustafsson JA:
ERbeta in CNS: New roles in development and function. Prog Brain
Res. 181:233–250. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Zuloaga DG, Puts DA, Jordan CL and
Breedlove SM: The role of androgen receptors in the masculinization
of brain and behavior: What we've learned from the testicular
feminization mutation. Horm Behav. 53:613–626. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Biegon A: In vivo visualization of
aromatase in animals and humans. Front Neuroendocrinol. 40:42–51.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Kudwa AE, Bodo C, Gustafsson JA and
Rissman EF: A previously uncharacterized role for estrogen receptor
beta: Defeminization of male brain and behavior. Proc Natl Acad Sci
USA. 102:4608–4612. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Skordis N, Kyriakou A, Dror S, Mushailov A
and Nicolaides NC: Gender dysphoria in children and adolescents: An
overview. Hormones (Athens). 19:267–276. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Henningsson S, Westberg L, Nilsson S,
Lundström B, Ekselius L, Bodlund O, Lindström E, Hellstrand M,
Rosmond R, Eriksson E and Landén M: Sex steroid-related genes and
male-to-female transsexualism. Psychoneuroendocrinology.
30:657–664. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Hare L, Bernard P, Sánchez FJ, Baird PN,
Vilain E, Kennedy T and Harley VR: Androgen receptor repeat length
polymorphism associated with male-to-female transsexualism. Biol
Psychiatry. 65:93–96. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Ujike H, Otani K, Nakatsuka M, Ishii K,
Sasaki A, Oishi T, Sato T, Okahisa Y, Matsumoto Y, Namba Y, et al:
Association study of gender identity disorder and sex
hormone-related genes. Prog Neuropsychopharmacol Biol Psychiatry.
33:1241–1244. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Fernández R, Esteva I, Gómez-Gil E, Rumbo
T, Almaraz MC, Roda E, Haro-Mora JJ, Guillamón A and Pásaro E:
Association study of ERβ, AR and CYP19A1 genes and MtF
transsexualism. J Sex Med. 11:2986–2994. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Cortés-Cortés J, Fernández R, Teijeiro N,
Gómez-Gil E, Esteva I, Almaraz MC, Guillamón A and Pásaro E:
Genotypes and Haplotypes of the Estrogen Receptor α Gene (ESR1) Are
Associated With Female-to-Male Gender Dysphoria. J Sex Med.
14:464–472. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Fernández R, Guillamon A, Cortés-Cortés J,
Gómez-Gil E, Jácome A, Esteva I, Almaraz M, Mora M, Aranda G and
Pásaro E: Molecular basis of Gender Dysphoria: Androgen and
estrogen receptor interaction. Psychoneuroendocrinology.
98:161–167. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Foreman M, Hare L, York K, Balakrishnan K,
Sánchez FJ, Harte F, Erasmus J, Vilain E and Harley VR: Genetic
link between gender dysphoria and sex hormone signaling. J Clin
Endocrinol Metab. 104:390–396. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Ramírez KDV, Fernández R, Delgado-Zayas E,
Gómez-Gil E, Esteva I, Guillamon A and Pásaro E: Implications of
the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological
Basis of Gender Incongruence. Sex Med. 9:1003682021. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Nilsson S, Mäkelä S, Treuter E, Tujague M,
Thomsen J, Andersson G, Enmark E, Pettersson K, Warner M and
Gustafsson JA: Mechanisms of estrogen action. Physiol Rev.
81:1535–1565. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
McKenna NJ, Lanz RB and O'Malley BW:
Nuclear receptor coregulators: Cellular and molecular biology.
Endocr Rev. 20:321–344. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Yi P, Wang Z, Feng Q, Pintilie GD, Foulds
CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W and O'Malley BW:
Structure of a biologically active estrogen receptor-coactivator
complex on DNA. Mol Cell. 57:1047–1058. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Maioli S, Leander K, Nilsson P and
Nalvarte I: Estrogen receptors and the aging brain. Essays Biochem.
65:913–925. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Osterlund MK and Hurd YL: Estrogen
receptors in the human forebrain and the relation to
neuropsychiatric disorders. Prog Neurobiol. 64:251–267. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Mehra RD, Sharma K, Nyakas C and Vij U:
Estrogen receptor alpha and beta immunoreactive neurons in normal
adult and aged female rat hippocampus: A qualitative and
quantitative study. Brain Res. 1056:22–35. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
González M, Cabrera-Socorro A,
Pérez-García CG, Fraser JD, López FJ, Alonso R and Meyer G:
Distribution patterns of estrogen receptor alpha and beta in the
human cortex and hippocampus during development and adulthood. J
Comp Neurol. 503:790–802. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Toffoletto S, Lanzenberger R, Gingnell M,
Sundström-Poromaa I and Comasco E: Emotional and cognitive
functional imaging of estrogen and progesterone effects in the
female human brain: A systematic review. Psychoneuroendocrinology.
50:28–52. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Waters EM, Yildirim M, Janssen WG, Lou WY,
McEwen BS, Morrison JH and Milner TA: Estrogen and aging affect the
synaptic distribution of estrogen receptor β-immunoreactivity in
the CA1 region of female rat hippocampus. Brain Res. 1379:86–97.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Morrison JH, Brinton RD, Schmidt PJ and
Gore AC: Estrogen, menopause and the aging brain: How basic
neuroscience can inform hormone therapy in women. J Neurosci.
26:10332–10348. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Dwyer JB, Aftab A, Radhakrishnan R, Widge
A, Rodriguez CI, Carpenter LL, Nemeroff CB, McDonald WM and Kalin
NH; APA Council of Research Task Force on Novel Biomarkers and
Treatments, : Hormonal treatments for major depressive disorder:
State of the Art. Am J Psychiatry. 177:686–705. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Goveas JS, Espeland MA, Woods NF,
Wassertheil-Smoller S and Kotchen JM: Depressive symptoms and
incidence of mild cognitive impairment and probable dementia in
elderly women: The Women's Health Initiative Memory Study. J Am
Geriatr Soc. 59:57–66. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Kilpi F, Soares ALG, Fraser A, Nelson SM,
Sattar N, Fallon SJ, Tilling K and Lawlor DA: Changes in six
domains of cognitive function with reproductive and chronological
ageing and sex hormones: A longitudinal study in 2411 UK mid-life
women. BMC Womens Health. 20:1772020. View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Wood Alexander M, Wu CY, Coughlan GT, Puri
T, Buckley RF, Palta P, Swardfager W, Masellis M, Galea LAM,
Einstein G, et al: Associations between age at menopause, vascular
risk and 3-year cognitive change in the canadian longitudinal study
on aging. Neurology. 102:e2092982024. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Georgakis MK, Kalogirou EI, Diamantaras
AA, Daskalopoulou SS, Munro CA, Lyketsos CG, Skalkidou A and
Petridou ET: Age at menopause and duration of reproductive period
in association with dementia and cognitive function: A systematic
review and meta-analysis. Psychoneuroendocrinology. 73:224–243.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Song YJ, Li SR, Li XW, Chen X, Wei ZX, Liu
QS and Cheng Y: The effect of estrogen replacement therapy on
Alzheimer's disease and parkinson's disease in postmenopausal
women: A meta-analysis. Front Neurosci. 14:1572020. View Article : Google Scholar : PubMed/NCBI
|
