Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
December-2024 Volume 30 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2024 Volume 30 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts

  • Authors:
    • Demin Lv
    • Bingxia Li
    • Zhen Liu
    • Qing Zhang
    • Sucheng Cao
    • Yanlong Xu
    • Zheng Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Traumatic Orthopedics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China, Department of Stomatology, Zhenjiang 359th Hospital, Zhenjiang, Jiangsu 212001, P.R. China, Department of Neurosurgery, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China, Department of Traumatic Orthopedics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China, Department of Emergency Services, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China, Department of Emergency Services, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China, Department of Medical Ultrasonics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China
    Copyright: © Lv et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 241
    |
    Published online on: October 15, 2024
       https://doi.org/10.3892/mmr.2024.13365
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Addressing the repair and regeneration of large bone defects poses significant challenges in bone tissue engineering. Despite the abundant evidence demonstrating the positive role of MSCs in osteogenesis, their limited osteogenic differentiation ability still needs to be improved. The present study used lipopolysaccharide (LPS) to enhance the osteogenic properties of ecto‑mesenchymal stem cells (EMSCs). Human nasal respiratory mucosa‑derived EMSCs were cultured on plates and stimulated with LPS for 5 days prior to undergoing osteogenic differentiation. The findings revealed that LPS effectively stimulated the osteogenic differentiation capacity of EMSCs, as evidenced by heightened alkaline phosphatase activity, elevated expression levels of osteogenic‑related proteins and enhanced mineralization of EMSCs. The present study also demonstrated that the augmentation occurred due to increased IL‑10 levels, although it was not solely attributable to this factor. Together, the findings illustrated that the LPS‑mediated adaptation of EMSCs is an active process driving osteogenic differentiation and could be a novel strategy for bone regeneration.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

View References

1 

Rayat Pisheh H, Ansari M and Eslami H: How is mechanobiology involved in bone regenerative medicine? Tissue Cell. 76:1018212022. View Article : Google Scholar : PubMed/NCBI

2 

Dec P, Modrzejewski A and Pawlik A: Existing and novel biomaterials for bone tissue engineering. Int J Mol Sci. 24:5292022. View Article : Google Scholar : PubMed/NCBI

3 

Li S, Liu J, Liu S, Jiao W and Wang X: Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis. J Nanobiotechnology. 19:3432021. View Article : Google Scholar : PubMed/NCBI

4 

Li S, Tian X, Fan J, Tong H, Ao Q and Wang X: Chitosans for tissue repair and organ three-dimensional (3D) bioprinting. Micromachines (Basel). 10:7652019. View Article : Google Scholar : PubMed/NCBI

5 

Yuan G, Li Z, Lin X, Li N and Xu R: New perspective of skeletal stem cells. Biomater Transl. 3:280–294. 2022.PubMed/NCBI

6 

Benayahu D: Mesenchymal stem cell differentiation and usage for biotechnology applications: Tissue engineering and food manufacturing. Biomater Transl. 3:17–23. 2022.PubMed/NCBI

7 

Charbord P: Bone marrow mesenchymal stem cells: Historical overview and concepts. Hum Gene Ther. 21:1045–1056. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Wang D, Cao H, Hua W, Gao L, Yuan Y, Zhou X and Zeng Z: Mesenchymal stem cell-derived extracellular vesicles for bone defect repair. membranes (basel). 12:7162022. View Article : Google Scholar : PubMed/NCBI

9 

Li S, Liu J, Liu S, Jiao W and Wang X: Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis. J Nanobiotechnology. 19:1942021. View Article : Google Scholar : PubMed/NCBI

10 

Lin H, Sohn J, Shen H, Langhans MT and Tuan RS: Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing. Biomaterials. 203:96–110. 2019. View Article : Google Scholar : PubMed/NCBI

11 

Delorme B, Nivet E, Gaillard J, Häupl T, Ringe J, Devèze A, Magnan J, Sohier J, Khrestchatisky M, Roman FS, et al: The human nose harbors a niche of olfactory ectomesenchymal stem cells displaying neurogenic and osteogenic properties. Stem Cells Dev. 19:853–866. 2010. View Article : Google Scholar : PubMed/NCBI

12 

Patthey C, Schlosser G and Shimeld SM: The evolutionary history of vertebrate cranial placodes-I: Cell type evolution. Dev Biol. 389:82–97. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Diogo R, Kelly RG, Christiaen L, Levine M, Ziermann JM, Molnar JL, Noden DM and Tzahor E: A new heart for a new head in vertebrate cardiopharyngeal evolution. Nature. 520:466–473. 2015. View Article : Google Scholar : PubMed/NCBI

14 

Achilleos A and Trainor PA: Neural crest stem cells: Discovery, properties and potential for therapy. Cell Res. 22:288–304. 2012. View Article : Google Scholar : PubMed/NCBI

15 

Trainor PA: Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention. Am J Med Genet A. 52A:2984–2994. 2010. View Article : Google Scholar : PubMed/NCBI

16 

Srinivasan A, Teo N, Poon KJ, Tiwari P, Ravichandran A, Wen F, Teoh SH, Lim TC and Toh YC: Comparative craniofacial bone regeneration capacities of mesenchymal stem cells derived from human neural crest stem cells and bone marrow. ACS Biomater Sci Eng. 7:207–221. 2021. View Article : Google Scholar : PubMed/NCBI

17 

Shi W, Zhang X, Bian L, Dai Y, Wang Z, Zhou Y, Yu S, Zhang Z, Zhao P, Tang H, et al: Alendronate crosslinked chitosan/polycaprolactone scaffold for bone defects repairing. Int J Biol Macromol. 204:441–456. 2022. View Article : Google Scholar : PubMed/NCBI

18 

Shi W, Bian L, Wu Y, Wang Z, Dai Y, Zhou Y, Meng P, Wang Q, Zhang Z, Zhao X, et al: Enhanced bone regeneration using a ZIF-8-Loaded fibrin composite scaffold. Macromol Biosci. 22:e21004162022. View Article : Google Scholar : PubMed/NCBI

19 

Li S, Wang J, Han Y, Li X, Liu C, Lv Z, Wang X, Tang X and Wang Z: Carbenoxolone inhibits mechanical stress-induced osteogenic differentiation of mesenchymal stem cells by regulating p38 MAPK phosphorylation. Exp Ther Med. 15:2798–2803. 2018.PubMed/NCBI

20 

Yuan L, You H, Qin N and Zuo W: Interleukin-10 modulates the metabolism and osteogenesis of human dental pulp stem cells. Cell Reprogram. 23:270–276. 2021. View Article : Google Scholar : PubMed/NCBI

21 

Su W, Wan Q, Huang J, Han L, Chen X, Chen G, Olsen N, Zheng SG and Liang D: Culture medium from TNF-α-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms. J Allergy Clin Immunol. 136:423–432.e8. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Liu H, Zhu X, Cao X, Chi A, Dai J, Wang Z, Deng C and Zhang M: IL-1β-primed mesenchymal stromal cells exert enhanced therapeutic effects to alleviate Chronic Prostatitis/Chronic Pelvic Pain Syndrome through systemic immunity. Stem Cell Res Ther. 12:5142021. View Article : Google Scholar : PubMed/NCBI

23 

Vallés G, Bensiamar F, Maestro-Paramio L, García-Rey E, Vilaboa N and Saldaña L: Influence of inflammatory conditions provided by macrophages on osteogenic ability of mesenchymal stem cells. Stem Cell Res Ther. 11:572020. View Article : Google Scholar : PubMed/NCBI

24 

Mahon OR, Browe DC, Gonzalez-Fernandez T, Pitacco P, Whelan IT, Von Euw S, Hobbs C, Nicolosi V, Cunningham KT, Mills KHG, et al: Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner. Biomaterials. 239:1198332020. View Article : Google Scholar : PubMed/NCBI

25 

Shi W, Que Y, Lv D, Bi S, Xu Z, Wang D and Zhang Z: Overexpression of TG2 enhances the differentiation of ectomesenchymal stem cells into neuron-like cells and promotes functional recovery in adult rats following spinal cord injury. Mol Med Rep. 20:2763–2773. 2019.PubMed/NCBI

26 

Shi W, Bian L, Lv D, Bi S, Dai Y, Yang K, Lu H, Zhou H, Que Y, Wang D, et al: Enhanced neural differentiation of neural stem cells by sustained release of Shh from TG2 gene-modified EMSC co-culture in vitro. Amino Acids. 53:11–22. 2021. View Article : Google Scholar : PubMed/NCBI

27 

Ouyang W, Rutz S, Crellin NK, Valdez PA and Hymowitz SG: Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol. 29:71–109. 2011. View Article : Google Scholar : PubMed/NCBI

28 

Fuchs S, Dohle E and Kirkpatrick CJ: Sonic Hedgehog-mediated synergistic effects guiding angiogenesis and osteogenesis. Vitam Horm. 88:491–506. 2012. View Article : Google Scholar : PubMed/NCBI

29 

Ma D, Yu H, Xu S, Wang H, Zhang X, Ning T and Wu B: Stathmin inhibits proliferation and differentiation of dental pulp stem cells via sonic hedgehog/Gli. J Cell Mol Med. 22:3442–3451. 2018. View Article : Google Scholar : PubMed/NCBI

30 

Bai Y, Zhang W, Hao L, Zhao Y, Tsai IC, Qi Y and Xu Q: Acetyl-CoA-dependent ac4C acetylation promotes the osteogenic differentiation of LPS-stimulated BMSCs. Int Immunopharmacol. 133:1121242024. View Article : Google Scholar : PubMed/NCBI

31 

Huang Z, Chen G, Wu H, Huang X, Xu R, Deng F and Li Y: Ebselen restores peri-implantitis-induced osteogenic inhibition via suppressing BMSCs ferroptosis. Exp Cell Res. 427:1136122023. View Article : Google Scholar : PubMed/NCBI

32 

Amarasekara DS, Kim S and Rho J: Regulation of osteoblast differentiation by cytokine networks. Int J Mol Sci. 22:28512021. View Article : Google Scholar : PubMed/NCBI

33 

Zhang SX, Wang JJ, Starr CR, Lee EJ, Park KS, Zhylkibayev A, Medina A, Lin JH and Gorbatyuk M: The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease. Prog Retin Eye Res. 98:1012312024. View Article : Google Scholar : PubMed/NCBI

34 

Takebe H, Shalehin N, Hosoya A, Shimo T and Irie K: Sonic hedgehog regulates bone fracture healing. Int J Mol Sci. 21:6772020. View Article : Google Scholar : PubMed/NCBI

35 

Guan CC, Yan M, Jiang XQ, Zhang P, Zhang XL, Li J, Ye DX and Zhang FQ: Sonic hedgehog alleviates the inhibitory effects of high glucose on the osteoblastic differentiation of bone marrow stromal cells. Bone. 45:1146–1152. 2009. View Article : Google Scholar : PubMed/NCBI

36 

Wang Y, Zhang H, Hu Y, Jing Y, Geng Z and Su J: Bone repair biomaterials: A perspective from immunomodulation. Adv Funct Mater. 32:22086392022. View Article : Google Scholar : PubMed/NCBI

37 

Wang F, Gu Z, Yin Z, Zhang W, Bai L and Su J: Cell unit-inspired natural nano-based biomaterials as versatile building blocks for bone/cartilage regeneration. J Nanobiotechnology. 21:2932023. View Article : Google Scholar : PubMed/NCBI

38 

Zhang S, Zhao G, Mahotra M, Ma S, Li W, Lee HW, Yu H, Sampathkumar K, Xie D, Guo J and Loo SCJ: Chitosan nanofibrous scaffold with graded and controlled release of ciprofloxacin and BMP-2 nanoparticles for the conception of bone regeneration. Int J Biol Macromol. 254((Pt 2)): 1279122024. View Article : Google Scholar : PubMed/NCBI

39 

Liu G, Ma M, Yang H, He W, Xie Y, Li J, Li J, Zhao F and Zheng Y: Chitosan/polydopamine/octacalcium phosphate composite microcarrier simulates natural bone components to induce osteogenic differentiation of stem cells. Biomater Adv. 154:2136422023. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Lv D, Li B, Liu Z, Zhang Q, Cao S, Xu Y and Zhang Z: LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts. Mol Med Rep 30: 241, 2024.
APA
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., & Zhang, Z. (2024). LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts. Molecular Medicine Reports, 30, 241. https://doi.org/10.3892/mmr.2024.13365
MLA
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., Zhang, Z."LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts". Molecular Medicine Reports 30.6 (2024): 241.
Chicago
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., Zhang, Z."LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts". Molecular Medicine Reports 30, no. 6 (2024): 241. https://doi.org/10.3892/mmr.2024.13365
Copy and paste a formatted citation
x
Spandidos Publications style
Lv D, Li B, Liu Z, Zhang Q, Cao S, Xu Y and Zhang Z: LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts. Mol Med Rep 30: 241, 2024.
APA
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., & Zhang, Z. (2024). LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts. Molecular Medicine Reports, 30, 241. https://doi.org/10.3892/mmr.2024.13365
MLA
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., Zhang, Z."LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts". Molecular Medicine Reports 30.6 (2024): 241.
Chicago
Lv, D., Li, B., Liu, Z., Zhang, Q., Cao, S., Xu, Y., Zhang, Z."LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts". Molecular Medicine Reports 30, no. 6 (2024): 241. https://doi.org/10.3892/mmr.2024.13365
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team