[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Yang,Lina; Yang,Xinrui; Tang,Yiwei; Zhang,Defu; Zhu,Lijie; Wang,Shengnan; Wang,Bo; Ma,Tao

doi:10.3892/mmr.2026.13890

June-2026 Volume 33 Issue 6

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

June-2026 Volume 33 Issue 6

Full Size Image

Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Authors:
- Lina Yang
- Xinrui Yang
- Yiwei Tang
- Defu Zhang
- Lijie Zhu
- Shengnan Wang
- Bo Wang
- Tao Ma
View Affiliations / Copyright

Affiliations: College of Food Science and Technology, Bohai University, Jinzhou, Liaoning 121013, P.R. China, Center for Therapeutic Research of Hepatocarcinoma, Beijing 302 Hospital, Beijing 100039, P.R. China

Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 180
|
Published online on: April 27, 2026

https://doi.org/10.3892/mmr.2026.13890
Expand metrics +

Article

Mol Med Rep 17: [Related article:] 7545–7552, 2018; DOI: 10.3892/mmr.2018.8828

Following the publication of the above article, a concerned author drew to the authors’ attention that, in Fig. 1B on p. 7548, the first two lanes for the lower set of β-actin western blots were unexpectedly similar to the data shown for the ATM protein blots in the third and fourth lanes in the same figure part. In addition, the upper set of β-actin western blots featured in Fig. 1B were also strikingly similar to the blots shown for the Bax protein in Fig. 2 on p. 6549. Moreover, an independent analysis of the data in this paper undertaken by the Editorial Office also revealed that the TAp73 and GRAMD protein blots shown in Fig. 2 were very similar.

$Effects of NU7026 and X-rays on growth, DNA damage and apoptosis in A549 cells. (A) The survival fraction was calculated after 0, 2, 4, 6 and 8 Gy X-ray irradiation. (B) Protein levels of DNA-PK and ATM were determined by western blotting 24 h post-treatment, following treatment with no-irradiation, 10 µM NU7026, 4 Gy X-rays and 10 µM NU7026+4 Gy X-rays. (C) The survival fraction was calculated after 10 µM NU7026 and 4 Gy X-ray irradiation. ***P<0.001. (D) γH2AX foci were imaged and detected by immunofluorescence 0.5 h post-irradiation. (E) Apoptosis was analyzed by flow cytometry after Annexin V/PI staining 24 h post-irradiation.$

Figure 1.

Effects of NU7026 and X-rays on growth, DNA damage and apoptosis in A549 cells. (A) The survival fraction was calculated after 0, 2, 4, 6 and 8 Gy X-ray irradiation. (B) Protein levels of DNA-PK and ATM were determined by western blotting 24 h post-treatment, following treatment with no-irradiation, 10 µM NU7026, 4 Gy X-rays and 10 µM NU7026+4 Gy X-rays. (C) The survival fraction was calculated after 10 µM NU7026 and 4 Gy X-ray irradiation. ***P<0.001. (D) γH2AX foci were imaged and detected by immunofluorescence 0.5 h post-irradiation. (E) Apoptosis was analyzed by flow cytometry after Annexin V/PI staining 24 h post-irradiation.

Figure 2.

Effects of NU7026 and X-rays on expression of apoptosis-related proteins in A549 cells. The protein levels of p53, DNp73, TAp73, GRAMD4, Bcl-2 and Bax were determined by western blotting 24 h post-irradiation, following treatment with 10 µM NU7026 for 30 min and 4 Gy X-rays. ***P<0.001 vs. the control group, #P<0.05 and ##P<0.01 vs. the 4 Gy group.

After having re-assessed these figures, the authors have submitted corrected versions of Figs. 1 and 2, as shown on the next page, featuring revised data for the upper and lower sets of β-actin blots in Fig. 1, and the TAp73 blots and certain of the β-actin blots in Fig. 2. Note that these errors did not affect the results or the main conclusions reported in the study. All the authors approve of the publication of this corrigendum, and are grateful to the Editor of Molecular Medicine Reports for allowing them the opportunity to publish this. The authors regret their oversight in allowing these errors to be included in the paper, and apologize to the readership for any inconvenience caused.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

This article is mentioned in:

Article

Figure 1.

Figure 2.

Related Articles