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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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January-February 2010 Volume 3 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls

  • Authors:
    • Andreas Lewander
    • Gunnar Arbman
    • Xiao F. Sun
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Institute of Clinical and Experimental Medicine, University of Linköping, Linköping, Sweden
  • Pages: 69-74
    |
    Published online on: January 1, 2010
       https://doi.org/10.3892/mmr_00000220
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Abstract

To investigate whether a -708ins/del8 polymorphism in the promoter region of the NFKBIA gene is related to colorectal cancer risk and clinicopathological variables, we genotyped 92 Swedish and 93 Chinese patients as well as 174 Swedish and 159 Chinese healthy controls by polymerase chain reaction-single stranded conformation polymorphism and DNA sequencing. The -708/del8 polymorphism was found in two Swedish patients and eight Swedish controls, but was absent in the Chinese population. However, among the Chinese population we found other mutations in three patients and in one control. In conclusion, the -708ins/del8 polymorphism is too rare to have a major impact on colorectal cancer incidence in the two populations.

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Copy and paste a formatted citation
Spandidos Publications style
Lewander A, Arbman G and Sun XF: Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls . Mol Med Rep 3: 69-74, 2010.
APA
Lewander, A., Arbman, G., & Sun, X.F. (2010). Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls . Molecular Medicine Reports, 3, 69-74. https://doi.org/10.3892/mmr_00000220
MLA
Lewander, A., Arbman, G., Sun, X. F."Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls ". Molecular Medicine Reports 3.1 (2010): 69-74.
Chicago
Lewander, A., Arbman, G., Sun, X. F."Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls ". Molecular Medicine Reports 3, no. 1 (2010): 69-74. https://doi.org/10.3892/mmr_00000220
Copy and paste a formatted citation
x
Spandidos Publications style
Lewander A, Arbman G and Sun XF: Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls . Mol Med Rep 3: 69-74, 2010.
APA
Lewander, A., Arbman, G., & Sun, X.F. (2010). Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls . Molecular Medicine Reports, 3, 69-74. https://doi.org/10.3892/mmr_00000220
MLA
Lewander, A., Arbman, G., Sun, X. F."Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls ". Molecular Medicine Reports 3.1 (2010): 69-74.
Chicago
Lewander, A., Arbman, G., Sun, X. F."Polymorphism in the promoter region of the NFKBIA gene is rare in Swedish and Chinese colorectal cancer patients and controls ". Molecular Medicine Reports 3, no. 1 (2010): 69-74. https://doi.org/10.3892/mmr_00000220
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