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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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November-December 2010 Volume 1 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

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Review Open Access

MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)

  • Authors:
    • Megumi Yanokura
    • Kouji Banno
    • Yusuke Kobayashi
    • Iori Kisu
    • Arisa Ueki
    • Asuka Ono
    • Kennta Masuda
    • Hiroyuki Nomura
    • Akira Hirasawa
    • Nobuyuki Susumu
    • Daisuke Aoki
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo 160-8582, Japan
  • Pages: 935-940
    |
    Published online on: September 22, 2010
       https://doi.org/10.3892/ol.2010.173
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Abstract

MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 base pairs that regulate the expression of genes by targeting messenger RNA with complementarity with the miRNA base sequence. Regulation of gene expression by miRNAs is crucial in cellular development and differentiation, and recent studies suggest a relationship between human diseases and the breakdown of gene silencing mechanisms induced by miRNA abnormalities. In particular, abnormal miRNA expression has been detected in various types of cancer and the target genes have been identified. These results indicate that miRNAs act in a manner equivalent to oncogenes or tumor suppressors. miRNAs may also serve as diagnostic biomarkers and therapeutic targets. In this review, we introduce the latest findings on miRNAs in human endometrial cancer, a common malignancy, and discuss the potential of miRNAs as biomarkers and targets for molecular therapy.
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Copy and paste a formatted citation
Spandidos Publications style
Yanokura M, Banno K, Kobayashi Y, Kisu I, Ueki A, Ono A, Masuda K, Nomura H, Hirasawa A, Susumu N, Susumu N, et al: MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review). Oncol Lett 1: 935-940, 2010.
APA
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A. ... Aoki, D. (2010). MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review). Oncology Letters, 1, 935-940. https://doi.org/10.3892/ol.2010.173
MLA
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A., Masuda, K., Nomura, H., Hirasawa, A., Susumu, N., Aoki, D."MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)". Oncology Letters 1.6 (2010): 935-940.
Chicago
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A., Masuda, K., Nomura, H., Hirasawa, A., Susumu, N., Aoki, D."MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)". Oncology Letters 1, no. 6 (2010): 935-940. https://doi.org/10.3892/ol.2010.173
Copy and paste a formatted citation
x
Spandidos Publications style
Yanokura M, Banno K, Kobayashi Y, Kisu I, Ueki A, Ono A, Masuda K, Nomura H, Hirasawa A, Susumu N, Susumu N, et al: MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review). Oncol Lett 1: 935-940, 2010.
APA
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A. ... Aoki, D. (2010). MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review). Oncology Letters, 1, 935-940. https://doi.org/10.3892/ol.2010.173
MLA
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A., Masuda, K., Nomura, H., Hirasawa, A., Susumu, N., Aoki, D."MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)". Oncology Letters 1.6 (2010): 935-940.
Chicago
Yanokura, M., Banno, K., Kobayashi, Y., Kisu, I., Ueki, A., Ono, A., Masuda, K., Nomura, H., Hirasawa, A., Susumu, N., Aoki, D."MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)". Oncology Letters 1, no. 6 (2010): 935-940. https://doi.org/10.3892/ol.2010.173
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