Surgical strategy of brain tumors adjacent to the optic radiation using diffusion tensor imaging-based tractography

Tatsuzawa,Kazunori; Owada,Kei; Sasajima,Hiroyasu; Yamada,Kei; Mineura,Katsuyoshi

doi:10.3892/ol.2010.177

Surgical strategy of brain tumors adjacent to the optic radiation using diffusion tensor imaging-based tractography

Authors:
- Kazunori Tatsuzawa
- Kei Owada
- Hiroyasu Sasajima
- Kei Yamada
- Katsuyoshi Mineura
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Affiliations: Department of Neurosurgery, Kyoto Prefectural Graduate School of Medicine, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan, Department of Radiology, Kyoto Prefectural Graduate School of Medicine, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Published online on: September 23, 2010 https://doi.org/10.3892/ol.2010.177
Pages: 1005-1010

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Abstract

The present study evaluated the efficacy of diffusion tensor imaging (DTI)-based tractography in the surgery of brain tumors adjacent to the optic radiation. Of the 14 surgical cases included, 11 had metastatic brain tumors and 3 cerebral gliomas. Additionally, 4 of the 14 patients had pre-operative visual field defects, while the remaining 10 patients experienced no visual impairment. The optic radiations on the lesion side were evident in all 14 patients. On the basis of these tractographic findings, we employed optimal surgical approaches in each patient to avoid injury to the eloquent neural structures, including optic radiation, during surgery. Successful surgical resection was performed in all 14 patients. Of the 14 patients, 2 with visual field defects during the pre-operative period showed improvement in their visual field, and the remaining 12 patients experienced no visual deterioration. DTI-based tractography thus is a feasible modality for the surgical planning of brain lesions adjacent to the optic radiation.

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1	Romano A, D’Andrea G, Minniti G, Mastronardi L, Ferrante L, Fantozzi LM and Bozzao A: Pre-surgical planning and MR-tractography utility in brain tumour resection. Eur Radiol. 19:2798–2808. 2009. View Article : Google Scholar : PubMed/NCBI
2	Witwer BP, Moftakhar R, Hasan KM, et al: Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J Neurosurg. 97:568–575. 2002. View Article : Google Scholar : PubMed/NCBI
3	Yu CS, Li KC, Xuan Y, Ji XM and Qin W: Diffusion tensor tractography in patients with cerebral tumors: a helpful technique for neurosurgical planning and postoperative assessment. Eur J Radiol. 56:197–204. 2005. View Article : Google Scholar : PubMed/NCBI
4	Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K and Yagi K: Relationships between brain tumor and optic tract or calcarine fissure are involved in visual deficits after surgery for brain tumor. Acta Neurochir. 152:637–642. 2010. View Article : Google Scholar : PubMed/NCBI
5	Yamada K, Kizu O, Mori S, et al: Brain fiber tracking with clinically feasible diffusion-tensor MR imaging: initial experience. Radiology. 227:295–301. 2003. View Article : Google Scholar : PubMed/NCBI
6	Clark CA, Barrick TR, Murphy MM and Bell BA: White matter fiber tracking in patients with space-occupying lesions of the brain: a new technique for neurosurgical planning? Neuroimage. 20:1601–1608. 2003. View Article : Google Scholar : PubMed/NCBI
7	Kikuta K, Takagi Y, Nozaki K, et al: Early experience with 3-T magnetic resonance tractography in the surgery of cerebral arteriovenous malformations in and around the visual pathway. Neurosurgery. 58:331–337. 2006. View Article : Google Scholar
8	González-Darder JM, González-López P, Talamantes F, Quilis V, Cortes V, Garcia-March G and Rordán P: Multimodal navigation in the functional microsurgical resection of intrinsic brain tumors located in eloquent motor areas: role of tractography. Neurosurg Focus. 28:E52010.PubMed/NCBI
9	Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, Sorensen AG and Fahlbusch R: Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery. Neurosurgery. 56:130–138. 2005.
10	Yamamoto T, Yamada K, Nishimura T and Kinoshita S: Tractography to depict three layers of visual field trajectories to the calcarine gyri. Am J Ophthalmol. 140:781–785. 2005. View Article : Google Scholar : PubMed/NCBI
11	Kamada K, Todo T, Morita A, et al: Functional monitoring for visual pathway using real-time visual evoked potentials and optic-radiation tractography. Neurosurgery. 57:121–127. 2005. View Article : Google Scholar : PubMed/NCBI
12	Roux FE, Ibarrola D, Lotterie JA, Chollet F and Berry I: Perimetric visual field and functional MRI correlation: implications for image-guided surgery in occipital brain tumours. J Neurol Neurosurg Psychiatry. 71:505–514. 2001. View Article : Google Scholar : PubMed/NCBI
13	Duffau H, Velut S, Mitchell MC, Gatignol P and Capelle L: Intra-operative mapping of the subcortical visual pathways using direct electrical stimulations. Acta Neurochir. 146:265–270. 2004. View Article : Google Scholar : PubMed/NCBI
14	Yamada K, Sakai K, Akazawa K, Yuen S and Nishimura T: MR tractography: a review of its clinical applications. Magn Reson Med Sci. 8:165–174. 2009. View Article : Google Scholar : PubMed/NCBI
15	Sincoff EH, Tan Y and Abdulrauf SI: White matter fiber dissection of the optic radiations of the temporal lobe and implications for surgical approaches to the temporal horn. J Neurosurg. 101:739–746. 2004. View Article : Google Scholar : PubMed/NCBI
16	Powell HWR, Parker GJM, Alexander DC, et al: MR tractography predicts visual field defects following temporal lobe resection. Neurology. 65:596–599. 2005. View Article : Google Scholar : PubMed/NCBI
17	Yogarajah M, Focke NK, Bonelli S, et al: Defining Meyer’s loop-temporal lobe resections, visual field deficits and diffusion tensor tractography. Brain. 132:1656–1668. 2009.
18	Kinoshita M, Yamada K, Hashimoto N, et al: Fiber-tracking does not accurately estimate size of fiber bundle in pathological condition: initial neurosurgical experience using neuronavigation and subcortical white matter stimulation. Neuroimage. 25:424–429. 2005. View Article : Google Scholar