Radiation recall dermatitis due to gemcitabine does not suggest the need to discontinue chemotherapy

Lock,Michael; Sinclair,Kevin; Welch,Stephen; Younus,Jawaid; Salim,Mohammad

doi:10.3892/ol.2010.195

January-February 2011 Volume 2 Issue 1

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January-February 2011 Volume 2 Issue 1

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Article

Radiation recall dermatitis due to gemcitabine does not suggest the need to discontinue chemotherapy

Authors:
- Michael Lock
- Kevin Sinclair
- Stephen Welch
- Jawaid Younus
- Mohammad Salim
View Affiliations / Copyright

Affiliations: Division of Radiation Oncology, London Regional Cancer Program, London, Ontario N6A 4L6, Canada, Division of Medical Oncology, London Regional Cancer Program, London, Ontario N6A 4L6, Canada
Pages: 85-90
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Published online on: October 5, 2010

https://doi.org/10.3892/ol.2010.195
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Abstract

Radiation recall is common following treatment with certain chemotherapy drugs and presents frequently as a skin reaction. With gemcitabine, such a recall phenomenon may affect internal tissues and presents itself as myositis. Although such reactions have previously been reported in the literature, whether or not to continue chemotherapy during such reactions remains controversial. We reported a case of radiation recall in a patient treated with gemcitabine and radiation therapy that presented as myositis. We were able to continue palliative chemotherapy and manage the side effects with supportive care treatment. This case report provides partial support for the continuation of chemotherapy when required even when a recall reaction is encountered.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Radiation recall dermatitis due to gemcitabine does not suggest the need to discontinue chemotherapy

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