Pituicytoma: Report of two cases

Mao,Zhigang; Xiao,Weiwei; Wang,Haijun; Li,Zhi; Huang,Quan; He,Dongsheng; Zhu,Yonghong

doi:10.3892/ol.2010.209

January-February 2011 Volume 2 Issue 1

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

January-February 2011 Volume 2 Issue 1

Full Size Image

Article

Pituicytoma: Report of two cases

Authors:
- Zhigang Mao
- Weiwei Xiao
- Haijun Wang
- Zhi Li
- Quan Huang
- Dongsheng He
- Yonghong Zhu
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, the First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Pathology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China
Pages: 37-41
|
Published online on: November 23, 2010

https://doi.org/10.3892/ol.2010.209
Expand metrics +

Abstract

This report describes two cases of pituicytoma. The two patients were female and presented with visual complaints, diabetes insipidus, headaches and menstrual disorders. The imaging characteristic was an intrasellar or suprasellar mass, and one mass originated in the pituitary stalk. The mass showed homogeneous enhancement with contrast administration. A hematoxylin and eosin stain showed a compact structure consisting of elongated, bipolar spindle cells arranged in interlacing fascicles or assuming a storiform pattern. Immunohistochemically, the tumor showed diffuse strong expression of S-100 protein, vimentin and epithelial membrane antigen, and glial fibrillary acidic protein was focally positive. The pituicytoma may have originated in the pituitary stalk and presented with diabetes insipidus, and the differential diagnosis should be compared with the pituitary stalk mass. Bleeding during resection was moderate, and surgery was regarded as the first choice of treatment for pituicytomas.

View Figures

View References

1	Scothorne CM: A glioma of the posterior lobe of the pituitary gland. J Pathol Bacteriol. 69:109–112. 1955. View Article : Google Scholar : PubMed/NCBI
2	Brat DJ, Scheithauer BW, Staugaitis SM, Holtzman RN, Morgello S and Burger PC: Pituicytoma: a distinctive lowgrade glioma of the neurohypophysis. Am J Surg Pathol. 24:362–368. 2000. View Article : Google Scholar : PubMed/NCBI
3	Ulm AJ, Yachnis AT, Brat DJ and Rhoton AL Jr: Pituicytoma: reports of two cases and clues regarding histogenesis. Neurosurgery. 54:753–757. 2004. View Article : Google Scholar : PubMed/NCBI
4	Wolfe SQ, Bruce J and Morcos JJ: Pituicytoma: case report. Neurosurgery. 63:E173–E174. 2008. View Article : Google Scholar : PubMed/NCBI
5	Takei H, Goodman JC, Tanaka S, Bhattacharjee MB, Bahrami A and Powell SZ: Pituicytoma incidentally found at autopsy. Pathol Int. 55:745–749. 2005. View Article : Google Scholar : PubMed/NCBI
6	Benveniste RJ, Purohit D and Byun H: Pituicytoma presenting with spontaneous hemorrhage. Pituitary. 9:53–58. 2006. View Article : Google Scholar
7	Figarella-branger D, Dufour H, Femandez C, Bouvier-Labit C, Grisoli F and Pellissier JF: Pituicytomas, a mis-diagnosed benign tumor of the neurohypophysis: report of three cases. Acta Neuropathol. 104:313–319. 2002.PubMed/NCBI
8	Kowalski RJ, Prayson RA and Mayberg MR: Pituicytoma. Ann Diagn Pathol. 8:290–294. 2004. View Article : Google Scholar
9	Uesaka T, Miyazono M, Nishio S and Iwaki T: Astrocytoma of the pituitary gland (pituicytoma): case report. Neuroradiology. 44:123–125. 2002. View Article : Google Scholar : PubMed/NCBI
10	Katsuta T, Inoue T, Nakagaki H, Takeshita M, Morimoto K and Iwaki T: Distinctions between pituicytoma and ordinary pilocytic astrocytoma. J Neurosurg. 98:404–406. 2003. View Article : Google Scholar : PubMed/NCBI
11	Gibbs WN, Monukie S, Linskey ME and Hasso AN: Pituicytoma: diagnostic features on selective carotid angiography and MR imaging. Am J Neuroradiol. 27:1639–1642. 2006.PubMed/NCBI
12	Thiryayi WA, Gnanalingham KK, Reid H, Heald A and Kearney T: Pituicytoma: a misdiagnosed benign tumour of the posterior pituitary. Br J Neurosurg. 21:47–48. 2007. View Article : Google Scholar : PubMed/NCBI
13	Nakasu Y, Nakasu S, Saito A, Horiguchi S and Kameya T: Pituicytoma: two case reports. Neurol Med Chir (Tokyo). 46:152–156. 2006. View Article : Google Scholar : PubMed/NCBI
14	Shah B, Lipper MH, Laws ER, Lopes B and Spellman MJ: Posterior pituitary astrocytoma: a rare tumor of the neurohypophysis: a case report. Am J Neuroradiol. 26:1858–1861. 2005.PubMed/NCBI
15	Han ZL, He DS, Mao ZG and Wang HJ: Cerebrospinal fluid rhinorrhea following trans-sphenoidal pituitary macroadenoma surgery: experience from 592 patients. Clin Neurol Neurosurg. 110:570–579. 2008. View Article : Google Scholar : PubMed/NCBI
16	Rossi ML, Bevan JS, Esiri MM, Hughes JT and Adams CB: Pituicytoma (pilocytic astrocytoma). Case report J Neurosurg. 67:768–772. 1987.PubMed/NCBI
17	Rousseaua A, Mokhtaria K and Duyckaertsa C: The 2007 WHO classification of tumors of the central nervous system – what has changed? Curr Opin Neurol. 21:720–727. 2008.
18	Shashikant C, Talal AS and Georges D: Epithelial membrane antigen in hematolymphoid neoplasms: a review. Appl Immunohistochem. 5:203–215. 1997. View Article : Google Scholar
19	Eng LF, Ghirnikar RS and Lee YL: Glial fibrillary acidic protein: GFAP-thirty-one-years (1969–2000). Neurochem Res. 25:1439–1451. 2000.PubMed/NCBI
20	Huang QL, Zhao SF, Gaudin A, Quennedey B and Gascuel J: Glial fibrillary acidic protein and vimentin expression in the frog olfactory system during metamorphosis. Neuro Report. 16:1439–1442. 2005.
21	Trembath D, Miller CR and Perry A: Gray zones in brain tumor classification evolving concepts. Adv Anat Pathol. 15:287–297. 2008. View Article : Google Scholar : PubMed/NCBI
22	Rupp D and Molitch M: Pituitary stalk lesions. Curr Opin Endocrinol Diabetes Obes. 15:339–345. 2008. View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Pituicytoma: Report of two cases

This article is mentioned in:

Abstract

Figure 1

Figure 2

Figure 3

Related Articles