|
1
|
Louis DN, Ohgaki H, Wiestler OD and
Cavenee WK: WHO Classification of Tumours of the Central Nervous
System. 4th edition. International Agency for Research on Cancer;
Lyon: 2007
|
|
2
|
Crawford JR, MacDonald TJ and Packer RJ:
Medulloblastoma in childhood: new biological advances. Lancet
Neurol. 6:1073–1085. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Clarke MF and Fuller M: Stem cells and
cancer: two faces of eve. Cell. 124:1111–1115. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Singh SK, Hawkins C, Clarke ID, et al:
Identification of human brain tumour initiating cells. Nature.
432:396–401. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hemmati HD, Nakano I, Lazareff JA, et al:
Cancerous stem cells can arise from pediatric brain tumors. Proc
Natl Acad Sci USA. 100:15178–15183. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Miraglia S, Godfrey W, Yin AH, et al: A
novel five-transmembrane hematopoietic stem cell antigen:
isolation, characterization, and molecular cloning. Blood.
90:5013–5021. 1997.PubMed/NCBI
|
|
7
|
Yu Y, Flint A, Dvorin EL and Bischoff J:
AC133–2, a novel isoform of human AC133 stem cell antigen. J Biol
Chem. 277:20711–20716. 2002.
|
|
8
|
Fargeas CA, Corbeil D and Huttner WB:
AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family
gene products in need of a rational nomenclature. Stem Cells.
21:506–508. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mizrak D, Brittan M and Alison MR: CD133:
molecule of the moment. J Pathol. 214:3–9. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Shmelkov SV, Butler JM, Hooper AT, et al:
CD133 expression is not restricted to stem cells, and both
CD133+ and CD133− metastatic colon cancer
cells initiate tumors. J Clin Invest. 118:2111–2120.
2008.PubMed/NCBI
|
|
11
|
Blazek ER, Foutch JL and Maki G: Daoy
medulloblastoma cells that express CD133 are radioresistant
relative to CD133− cells, and the CD133+
sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys.
67:1–5. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Srivastava VK and Nalbantoglu J: Flow
cytometric characterization of the DAOY medulloblastoma cell line
for the cancer stem-like phenotype. Cytometry A. 73:940–948. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Buckbinder L, Velasco-Miguel S, Chen Y, et
al: The p53 tumor suppressor targets a novel regulator of G protein
signaling. Proc Natl Acad Sci USA. 94:7868–7872. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Guarnaccia C, Pintar A and Pongor S: Exon
6 of human Jagged-1 encodes an autonomously folding unit. FEBS
Lett. 574:156–160. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Gilbertson RJ, Clifford SC, MacMeekin W,
et al: Expression of the ErbB-neuregulin signaling network during
human cerebellar development: implications for the biology of
medulloblastoma. Cancer Res. 58:3932–3941. 1998.
|
|
16
|
Takahashi K, Tanabe K, Ohnuki M, et al:
Induction of pluri-potent stem cells from adult human fibroblasts
by defined factors. Cell. 131:861–872. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Reya T and Clevers H: Wnt signalling in
stem cells and cancer. Nature. 434:843–850. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ruiz i Altaba A, Sanchez P and Dahmane N:
Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat
Rev Cancer. 2:361–372. 2002.PubMed/NCBI
|
|
19
|
Gilbertson RJ: Medulloblastoma: signalling
a change in treatment. Lancet Oncol. 5:209–218. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Brown CW, Houston-Hawkins DE, Woodruff TK
and Matzuk MM: Insertion of Inhbb into the Inhba locus rescues the
Inhba-null phenotype and reveals new activin functions. Nat Genet.
25:453–457. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
21
|
Holash J, Maisonpierre PC, Compton D, et
al: Vessel cooption, regression, and growth in tumors mediated by
angiopoietins and VEGF. Science. 284:1994–1998. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Garner CC, Tucker RP and Matus A:
Selective localization of messenger RNA for cytoskeletal protein
MAP2 in dendrites. Nature. 336:674–677. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Julien JP, Grosveld F, Yazdanbaksh K,
Flavell D, Meijer D and Mushynski W: The structure of a human
neurofilament gene (NF-L): a unique exon-intron organization in the
intermediate filament gene family. Biochim Biophys Acta. 909:10–20.
1987. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ango F, di Cristo G, Higashiyama H,
Bennett V, Wu P and Huang ZJ: Ankyrin-based subcellular gradient of
neurofascin, an immunoglobulin family protein, directs GABAergic
innervation at purkinje axon initial segment. Cell. 119:257–272.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Wingate RJ: The rhombic lip and early
cerebellar development. Curr Opin Neurobiol. 11:82–88. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Yuan W, Zhou L, Chen JH, Wu JY, Rao Y and
Ornitz DM: The mouse SLIT family: secreted ligands for ROBO
expressed in patterns that suggest a role in morphogenesis and axon
guidance. Dev Biol. 212:290–306. 1999. View Article : Google Scholar
|
|
27
|
Lafarga M, Crespo P, Berciano MT, Andres
MA and Leon J: Apolipoprotein E expression in the cerebellum of
normal and hypercholesterolemic rabbits. Brain Res Mol Brain Res.
21:115–123. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Hallahan AR, Pritchard JI, Chandraratna
RA, et al: BMP-2 mediates retinoid-induced apoptosis in
medulloblastoma cells through a paracrine effect. Nat Med.
9:1033–1038. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gumireddy K, Sutton LN, Phillips PC and
Reddy CD: All-transretinoic acid-induced apoptosis in human
medulloblastoma: activation of caspase-3/poly(ADP-ribose)
polymerase 1 pathway. Clin Cancer Res. 9:4052–4059. 2003.PubMed/NCBI
|
|
30
|
Goodrich LV, Milenkovic L, Higgins KM and
Scott MP: Altered neural cell fates and medulloblastoma in mouse
patched mutants. Science. 277:1109–1113. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Wechsler-Reya R and Scott MP: The
developmental biology of brain tumors. Annu Rev Neurosci.
24:385–428. 2001. View Article : Google Scholar
|
|
32
|
Yokota N, Nishizawa S, Ohta S, et al: Role
of Wnt pathway in medulloblastoma oncogenesis. Int J Cancer.
101:198–201. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yokota N, Mainprize TG, Taylor MD, et al:
Identification of differentially expressed and developmentally
regulated genes in medulloblastoma using suppression subtraction
hybridization. Oncogene. 23:3444–3453. 2004. View Article : Google Scholar
|
|
34
|
Fan X, Matsui W, Khaki L, et al: Notch
pathway inhibition depletes stem-like cells and blocks engraftment
in embryonal brain tumors. Cancer Res. 66:7445–7452. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Gilbertson R, Wickramasinghe C, Hernan R,
et al: Clinical and molecular stratification of disease risk in
medulloblastoma. Br J Cancer. 85:705–712. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
MacDonald TJ, Brown KM, LaFleur B, et al:
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK
pathway as therapeutic targets for metastatic disease. Nat Genet.
29:143–152. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
37
|
Gilbertson RJ and Clifford SC: PDGFRB is
overexpressed in metastatic medulloblastoma. Nat Genet. 35:197–198.
2003. View Article : Google Scholar : PubMed/NCBI
|
