1
|
Ambudkar SV, Dey S, Hrycyna CA,
Ramachandra M, Pastan I and Gottesman MM: Biochemical, cellular,
and pharmacological aspects of the multidrug transporter. Annu Rev
Pharmacol Toxicol. 39:361–398. 1999. View Article : Google Scholar : PubMed/NCBI
|
2
|
Deeley RG, Westlake C and Cole SP:
Transmembrane transport of endo- and xenobiotics by mammalian
ATP-binding cassette multidrug resistance proteins. Physiol Rev.
86:849–899. 2006. View Article : Google Scholar : PubMed/NCBI
|
3
|
Cui Y, Konig J, Buchholz JK, Spring H,
Leier I and Keppler D: Drug resistance and ATP-dependent conjugate
transport mediated by the apical multidrug resistance protein,
MRP2, permanently expressed in human and canine cells. Mol
Pharmacol. 55:929–937. 1999.
|
4
|
Kruh GD and Belinsk MG: The MRP family of
drug efflux pumps. Oncogene. 22:7537–7552. 2003. View Article : Google Scholar : PubMed/NCBI
|
5
|
Elion GB: The purine path to chemotherapy.
Science. 244:41–47. 1989. View Article : Google Scholar : PubMed/NCBI
|
6
|
Elgemeie GH: Thioguanine, mercaptopurine:
their analogs and nucleosides as antimetabolites. Curr Pharm Des.
9:2627–2642. 2003. View Article : Google Scholar : PubMed/NCBI
|
7
|
Fotoohi AK, Wrabel A, Moshfegh A, Peterson
C and Albertioni F: Molecular mechanisms underlying the enhanced
sensitivity of thiopurine-resistant T-lymphoblastic cell lines to
methyl mercaptopurine-riboside. Biochem Pharmacol. 72:816–823.
2006. View Article : Google Scholar : PubMed/NCBI
|
8
|
Juliano RL and Ling V: A surface
glycoprotein modulating drug permeability in Chinese hamster ovary
cell mutants. Biochim Biophys Acta. 455:152–162. 1976. View Article : Google Scholar : PubMed/NCBI
|
9
|
Plasschaert SL, de Bont ES, Boezen M, et
al: Expression of multidrug resistance-associated proteins predicts
prognosis in childhood and adult acute lymphoblastic leukemia. Clin
Cancer Res. 11:8661–8668. 2005. View Article : Google Scholar : PubMed/NCBI
|
10
|
Del Principe MI, del Poeta G, Maurillo L,
et al: P-glycoprotein and BCL-2 levels predict outcome in adult
acute lymphoblastic leukaemia. Br J Haematol. 121:730–738.
2003.PubMed/NCBI
|
11
|
Cole SP, Bhardwaj G, Gerlach JH, et al:
Overexpression of a transporter gene in a multidrug-resistant human
lung cancer cell line. Science. 258:1650–1654. 1992. View Article : Google Scholar : PubMed/NCBI
|
12
|
Doyle LA, Yang W, Abruzzo LV, et al: A
multidrug resistance transporter from human MCF-7 breast cancer
cells. Proc Natl Acad Sci USA. 95:15665–15670. 1998. View Article : Google Scholar : PubMed/NCBI
|
13
|
Lee K, Klein-Szanto AJ and Kruh GD:
Analysis of the MRP4 drug resistance profile in transfected NIH3T3
cells. J Natl Cancer Inst. 92:1934–1940. 2000. View Article : Google Scholar : PubMed/NCBI
|
14
|
Chen ZS, Lee K and Kruh GD: Transport of
cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug
resistance protein 4: resistance to 6-mercaptopurine and
6-thioguanine. J Biol Chem. 276:33747–33754. 2001. View Article : Google Scholar : PubMed/NCBI
|
15
|
Abbas-Terki T, Blanco-Bose W, Deglon N,
Pralong W and Aebischer P: Lentiviral-mediated RNA interference.
Hum Gene Ther. 13:2197–2201. 2002. View Article : Google Scholar : PubMed/NCBI
|
16
|
Guo Y, Kotova E, Chen ZS, Lee K,
Hopper-Borge E, Belinsky MG and Kruh GD: MRP8, ATP-binding cassette
C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance
factor for fluoropyrimidines 2′, 3′-dideoxycytidine and
9′-(2′-phosphonylmethoxyethyl) adenine. J Biol Chem.
278:29509–29514. 2003.PubMed/NCBI
|
17
|
Dean M, Hamon Y and Chimini G: The human
ATP-binding cassette (ABC) transporter superfamily. J Lipid Res.
42:1007–1017. 2001.PubMed/NCBI
|
18
|
Dean M, Rzhetsky A and Allikmets R: The
human ATP-binding cassette (ABC) transporter superfamily. Genome
Res. 11:1156–1166. 2001. View Article : Google Scholar : PubMed/NCBI
|
19
|
Annino L, Vegna ML, Camera A, et al:
Treatment of adult acute lymphoblastic leukemia (ALL): long-term
follow-up of the GIMEMA ALL 0288 randomized study. Blood.
99:863–871. 2002. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhang J, Visser F, Vickers MF, et al:
Uridine binding motifs of human concentrative nucleoside
transporters 1 and 3 produced in Saccharomyces cerevisiae.
Mol Pharmacol. 64:1512–1520. 2003. View Article : Google Scholar : PubMed/NCBI
|
21
|
Larson RA: The U.S. trials in adult acute
lymphoblastic leukemia. Ann Hematol. 83(Suppl 1): S127–S128.
2004.PubMed/NCBI
|
22
|
Norris MD, Smith J, Tanabe K, et al:
Expression of multidrug transporter MRP4/ABCC4 is a marker of poor
prognosis in neuroblastoma and confers resistance toirinotecan in
vitro. Mol Cancer Ther. 4:547–553. 2005. View Article : Google Scholar : PubMed/NCBI
|
23
|
Wijnholds J, Mol CA, van Deemter L, et al:
Multidrug-resistance protein 5 is a multispecific organic anion
transporter able to transport nucleoside analogs. Pro Natl Acad Sci
USA. 97:7476–7481. 2000. View Article : Google Scholar : PubMed/NCBI
|
24
|
Wielinga PR, Reid G, Challa EE, et al:
Thiopurine metabolism and identification of the thiopurine
metabolites transported by MRP4 and MRP5 overexpressed in human
embryonic kidney cells. Mol Pharmacol. 62:1321–1331. 2002.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Reid G, Wielinga P, Zelcer N, et al:
Characterization of the transport of nucleoside analog drugs by the
human multidrug resistance proteins MRP4 and MRP5. Mol Pharmacol.
63:1094–1103. 2003. View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang X, Furukawa T, Nitanda T, Okamoto M,
Sugimoto Y, Akiyama S and Baba M: Breast cancer resistance protein
(BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside
reverse transcriptase inhibitors. Mol Pharmacol. 63:65–72. 2003.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Chen ZS, Lee K, Walther S, Raftogianis RB,
Kuwano M, Zeng H and Kruh GD: Analysis of methotrexate and folate
transport by multidrug resistance protein 4 (ABCC4): MRP4 is a
component of the methotrexate efflux system. Cancer Res.
62:3144–3150. 2002.PubMed/NCBI
|
28
|
Peng XX, Shi Z, Damaraju VL, et al:
Up-regulation of MRP4 and down-regulation of influx transporters in
human leukemic cells with acquired resistance to 6-mercaptopurine.
Leuk Res. 32:799–809. 2008. View Article : Google Scholar : PubMed/NCBI
|
29
|
Kruh GD: Introduction to resistance to
anticancer agents. Oncogene. 22:7262–7264. 2003. View Article : Google Scholar : PubMed/NCBI
|
30
|
Smith KM, Slugoski MD, Loewen SK, Ng AM,
Yao SY, Chen XZ, et al: The broadly selective human
Na+/nucleoside cotransporter (hCNT3) exhibits novel
cation-coupled nucleoside transport characteristics. J Biol Chem.
280:25436–25499. 2005.PubMed/NCBI
|
31
|
Fotoohi AK, Lindqvist M, Peterson C and
Albertioni F: Involvement of the concentrative nucleoside
transporter 3 and equilibrative nucleoside transporter 2 in the
resistance of T-lymphoblastic cell lines to thiopurines. Biochem
Biophys Res Commun. 343:208–215. 2006. View Article : Google Scholar
|
32
|
Breuninger LM, Paul S, Gaughan K, Miki T,
Chan A, Aaronson SA and Kruh GD: Expression of multidrug associated
protein in NIH/3T3 cells confers multidrug resistance associated
with increased drug efflux and altered intracellular drug
distribution. Cancer Res. 55:5342–5347. 1995.
|
33
|
Clarke ML, Damaraju VL, Zhang J, et al:
The role of human nucleoside transporters in cellular uptake of
4′-thio-beta-D-arabinofuranosylcytosine and
beta-D-arabinosylcytosine. Mol Pharmacol. 70:303–310. 2006.
|
34
|
Cass CE, Young JD and Baldwin SA: Recent
advances in the molecular biology of nucleoside transporters of
mammalian cells, Biochem. Cell Biol. 76:761–770. 1998.PubMed/NCBI
|
35
|
Chen ZS, Aoki S, Komatsu M, Ueda K, et al:
Reversal of drug resistance mediated by multidrug resistance
protein (MRP) 1 by dual effects of agosterol A on MRP1 function.
Int J Cancer. 93:107–113. 2001. View Article : Google Scholar : PubMed/NCBI
|
36
|
Chen ZS, Robey RW, Belinsky MG, et al:
Transport of methotrexate, methotrexate polyglutamates, and
17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of
acquired mutations at R482 on methotrexate transport. Cancer Res.
63:4048–4054. 2003.PubMed/NCBI
|
37
|
Peng XX and Li YB: Induction of cellular
glutathione-linked enzymes and catalase by the unique
chemoprotective agent, 3H-1,2-dithiole-3-thione in rat
cardiomyocytes affords protection against oxidative cell injury.
Pharmacol Res. 45:491–497. 2002. View Article : Google Scholar
|
38
|
Bradford MM: A rapid and sensitive method
for the quantitation of microgram quantities of protein utilizing
the principle of protein-dye binding. Anal Biochem. 72:248–254.
1976. View Article : Google Scholar : PubMed/NCBI
|
39
|
Krynetskaia NF, Krynetski EY and Evans WE:
Human RNase H-mediated RNA cleavage from DNA-RNA duplexes is
inhibited by 6-deoxythioguanosine incorporation into DNA. Mol
Pharmacol. 56:841–848. 1999.PubMed/NCBI
|
40
|
Mcleod HL, Relling MV, Liu Q, Pui CH and
Evans WE: Polymorphic thiopurine methyltransferase in erythrocytes
is indicative of activity in leukemic blasts from children with
acute lymphoblastic leukemia. Blood. 85:1897–1902. 1995.PubMed/NCBI
|
41
|
Hart SM, Ganeshaguru K, Hoffbrand AV,
Prentice HG and Mehta AB: Expression of the multidrug
resistance-associated protein (MRP) in acute leukemia. Leukemia.
8:2163–2168. 1994.PubMed/NCBI
|
42
|
Wuchter C, Leonid K, Ruppert V, et al:
Clinical significance of P-glycoprotein expression and function for
response to induction chemotherapy, relapse rate and overall
survival in acute leukemia. Haematologica. 85:711–721.
2000.PubMed/NCBI
|
43
|
Kuwazuru Y, Yoshimura A, Hanada S, et al:
Expression of multidrug transporter, P-glycoprotein, in chronic
myelogenous leukemia cells in blast crisis. Br J Haematol.
74:24–29. 1990. View Article : Google Scholar : PubMed/NCBI
|
44
|
Zeng H, Lin ZP and Sartorelli AC:
Resistance to purine and pyrimidine nucleoside and nucleobase
analogs by the human MDR1 transfected murine leukemia cell line
L1210/VMDRC.06. Biochem Pharmacol. 68:911–921. 2004. View Article : Google Scholar : PubMed/NCBI
|
45
|
Loscher W and Potschka H: Blood-brain
barrier active efflux transporters: ATP-binding cassette gene
family. NeuroRx. 2:86–98. 2005. View Article : Google Scholar : PubMed/NCBI
|
46
|
De Graaf D, Sharma RC, Mechetner EB,
Schimke RT and Roninson IB: P-glycoprotein confers methotrexate
resistance in 3T6 cells with deficient carrier mediated
methotrexate uptake. Proc Natl Acad Sci USA. 93:1238–1242.
1996.PubMed/NCBI
|