Histologic coagulative tumour necrosis as a prognostic indicator of aggressiveness in renal, lung, thyroid and colorectal carcinomas: A brief review

  • Authors:
    • Rosario Caruso
    • Antonino Parisi
    • Anna Bonanno
    • Domenica Paparo
    • Emilia  Quattrocchi
    • Giovanni Branca
    • Marco Scardigno
    • Francesco Fedele
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  • Published online on: September 16, 2011     https://doi.org/10.3892/ol.2011.420
  • Pages: 16-18
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Abstract

Tumour growth involves two essential deviations from the normal state including the induction of proliferative stimuli, and simultaneous suppression of potentially compensatory cell death. It has been suggested that the development of invasive cancer involves a progressive switch from predominantly apoptotic to necrotic tumour cell death. The presence of tumour necrosis in pathologic specimens may not only reflect tumour biology, but also provide additional beneficial prognostic information. This review emphasises the role of tumour necrosis as an additional prognostic factor for patients with certain types of epithelial neoplasms.
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January 2012
Volume 3 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Caruso R, Parisi A, Bonanno A, Paparo D, Quattrocchi E, Branca G, Scardigno M and Fedele F: Histologic coagulative tumour necrosis as a prognostic indicator of aggressiveness in renal, lung, thyroid and colorectal carcinomas: A brief review. Oncol Lett 3: 16-18, 2012
APA
Caruso, R., Parisi, A., Bonanno, A., Paparo, D., Quattrocchi, E., Branca, G. ... Fedele, F. (2012). Histologic coagulative tumour necrosis as a prognostic indicator of aggressiveness in renal, lung, thyroid and colorectal carcinomas: A brief review. Oncology Letters, 3, 16-18. https://doi.org/10.3892/ol.2011.420
MLA
Caruso, R., Parisi, A., Bonanno, A., Paparo, D., Quattrocchi, E., Branca, G., Scardigno, M., Fedele, F."Histologic coagulative tumour necrosis as a prognostic indicator of aggressiveness in renal, lung, thyroid and colorectal carcinomas: A brief review". Oncology Letters 3.1 (2012): 16-18.
Chicago
Caruso, R., Parisi, A., Bonanno, A., Paparo, D., Quattrocchi, E., Branca, G., Scardigno, M., Fedele, F."Histologic coagulative tumour necrosis as a prognostic indicator of aggressiveness in renal, lung, thyroid and colorectal carcinomas: A brief review". Oncology Letters 3, no. 1 (2012): 16-18. https://doi.org/10.3892/ol.2011.420