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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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January 2012 Volume 3 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review

  • Authors:
    • Waseem Khaliq
    • Mohammad Farshad Bahador
    • Thomas Nichols Laurence
    • Ronald Andrew Sapiente
    • James Sheridan Lewis
    • David Lee Graham
  • View Affiliations / Copyright

    Affiliations: Instructor of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA, University of Missouri, Columbia, MO, USA, Department of Internal Medicine, University of Illinois College of Medicine, IL, USA, Department of Radiation Oncology, Carle Cancer Center/Mills Breast Cancer Institute, Urbana, IL, USA, Department of Pathology and Immunology, Washington University in St. Louis, MO, USA
  • Pages: 155-158
    |
    Published online on: October 13, 2011
       https://doi.org/10.3892/ol.2011.440
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Abstract

Ewing's sarcoma is the second most common primary sacral tumor. Ewing's sarcomas are rare, aggressive tumors with a tendency towards recurrence following resection and early metastasis. Although peak incidences are between the ages of 10 and 20 years, patients of younger or older age account for almost 30% of the cases. We report the case of a 52-year-old healthy female who presented with a 2-week history of pain in her right posterior thigh that was unable to be relieved by non‑steroidal anti-inflammatory medicine and physical therapy. Magnetic resonance imaging demonstrated an irregular right presacral mass and core needle biopsy revealed a small, round blue cell neoplasm. Staging workup was normal and an open biopsy was positive for the ES translocation (22q12). The patient was treated with 17 cycles of vincristine, adriamycin and cytoxan with mesna rescue, alternating with ifosfamide and etoposide in addition to external beam radiation. Post-treatment imaging demonstrated complete resolution of the tumor. Six weeks post‑treatment the patient presented with a recurrent tumor. This case emphasizes the importance of timely establishment of initial diagnosis, early metastasis in treatment responsive patients and under-utilization of positron emission tomography-computed tomography (PET-CT) during the treatment to detect sub-clinical metastasis.
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Copy and paste a formatted citation
Spandidos Publications style
Khaliq W, Bahador MF, Nichols Laurence T, Sapiente RA, Lewis JS and Graham DL: Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review. Oncol Lett 3: 155-158, 2012.
APA
Khaliq, W., Bahador, M.F., Nichols Laurence, T., Sapiente, R.A., Lewis, J.S., & Graham, D.L. (2012). Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review. Oncology Letters, 3, 155-158. https://doi.org/10.3892/ol.2011.440
MLA
Khaliq, W., Bahador, M. F., Nichols Laurence, T., Sapiente, R. A., Lewis, J. S., Graham, D. L."Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review". Oncology Letters 3.1 (2012): 155-158.
Chicago
Khaliq, W., Bahador, M. F., Nichols Laurence, T., Sapiente, R. A., Lewis, J. S., Graham, D. L."Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review". Oncology Letters 3, no. 1 (2012): 155-158. https://doi.org/10.3892/ol.2011.440
Copy and paste a formatted citation
x
Spandidos Publications style
Khaliq W, Bahador MF, Nichols Laurence T, Sapiente RA, Lewis JS and Graham DL: Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review. Oncol Lett 3: 155-158, 2012.
APA
Khaliq, W., Bahador, M.F., Nichols Laurence, T., Sapiente, R.A., Lewis, J.S., & Graham, D.L. (2012). Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review. Oncology Letters, 3, 155-158. https://doi.org/10.3892/ol.2011.440
MLA
Khaliq, W., Bahador, M. F., Nichols Laurence, T., Sapiente, R. A., Lewis, J. S., Graham, D. L."Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review". Oncology Letters 3.1 (2012): 155-158.
Chicago
Khaliq, W., Bahador, M. F., Nichols Laurence, T., Sapiente, R. A., Lewis, J. S., Graham, D. L."Ewing's Sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review". Oncology Letters 3, no. 1 (2012): 155-158. https://doi.org/10.3892/ol.2011.440
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