Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
January 2012 Volume 3 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January 2012 Volume 3 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells

  • Authors:
    • Samil Jung
    • Soonduck Lee
    • Jayhee Lee
    • ChenGping Li
    • Ji-Yeon Ohk
    • Hyeon‑Kyung Jeong
    • Seungkyu  Lee
    • Sangwoo Kim
    • Yunyeong Choi
    • Sunghak Kim
    • Heungwoo Lee
    • Myeong-Sok Lee
  • View Affiliations / Copyright

    Affiliations: Division of Biological Science and Research Center for Women's Diseases, Sookmyung Women's University, Seoul 140-742, Republic of Korea, Seoul Science High School, Seoul, Republic of Korea
  • Pages: 147-154
    |
    Published online on: October 18, 2011
       https://doi.org/10.3892/ol.2011.444
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Breast cancer is one of the most common types of cancer in women and is highly treatable by radiotherapy. However, repeated exposure to radiation results in tumor cell resistance. Understanding the molecular mechanisms involved in the response of tumors to γ-irradiation is important for improving radiotherapy. For this reason, we aimed to identify radiation-responsive genes at the protein level. In the present study, we observed differentially expressed proteins using 2D-PAGE and MALDI-TOF-MS for the global analysis of protein expression patterns in response to ionizing radiation (IR). When the expression patterns of proteins were compared to a control gel, numerous spots were found that differed greatly. Among them, 11 spots were found to be significantly different. One set of proteins (GH2, RGS17, BAK1, CCNH, TSG6, RAD51B, IGFBP1 and CASP14) was upregulated and another set of proteins (C1QRF, PLSCR2 and p34SE1-1) was downregulated after exposure to γ-rays. These proteins are known to be related to cell cycle control, apoptosis, DNA repair, cell proliferation and other signaling pathways.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

El-Deiry WS: The role of p53 in chemosensitivity and radio-sensitivity. Oncogene. 22:7486–7495. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Iliakis G, Wang Y, Guan J and Wang H: DNA damage checkpoint control in cells exposed to ionizing radiation. Oncogene. 22:5834–5847. 2003. View Article : Google Scholar : PubMed/NCBI

3 

Amundson SA, Myers TG and Fornace Jr: Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress. Oncogene. 17:3287–3299. 1998. View Article : Google Scholar : PubMed/NCBI

4 

Fornace AJ Jr, Amundson SA, Bittner M, Myers TG, Meltzer P, Weinsten JN and Trent J: The complexity of radiation stress reponse: analysis by informatics and functional genomics approaches. Gene Expr. 7:387–400. 1999.PubMed/NCBI

5 

King TC, Estalilla OC and Safran H: Role of p53 and p16 gene alterations in determining response to concurrent paclitaxel and radiation in solid tumor. Semin Radiat Oncol. 9:4–11. 1999.PubMed/NCBI

6 

Lu X and Lane DP: Differential induction of transcriptionally active p53 following UV or ionizing irradiation: defects in chromosome instability syndromes? Cell. 75:765–778. 1993. View Article : Google Scholar : PubMed/NCBI

7 

Keyse SM: The induction of gene expression in mammalian cells by radiation. Semin Cancer Biol. 4:119–128. 1993.PubMed/NCBI

8 

Iliakis G: Cell cycle regulation in irradiated and nonirradiated cells. Semin Oncol. 24:602–615. 1997.PubMed/NCBI

9 

Eckardt Schupp F and Klaus C: Radiation inducible DNA repair processes in eukaryotes. Biochimie. 81:161–171. 1999.PubMed/NCBI

10 

Maity A, McKenna WG and Muschel RJ: The molecular basis for cell cycle delays following ionizing radiation: a review. Radiother Oncol. 31:1–13. 1994. View Article : Google Scholar : PubMed/NCBI

11 

Forrester HB, Vidair CA, Albright N, Ling CC and Dewey WC: Using computerized video time lapse for quantifying cell death of Xirradiated rat embryo cells transfected with cmyc or cHaras. Cancer Res. 59:931–939. 1999.PubMed/NCBI

12 

Kasid U, Suy S, Dent P, Ray S, Whiteside TL and Sturgill TW: Activation of Raf by ionizing radiation. Nature. 382:813–816. 1996. View Article : Google Scholar : PubMed/NCBI

13 

Waldman T, Lengauer C, Kinzler KW and Vogelstein B: Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature. 381:713–716. 1996. View Article : Google Scholar : PubMed/NCBI

14 

El-Deiry WS: Regulation of p53 downstream genes. Semin Cancer Biol. 8:345–357. 1998. View Article : Google Scholar

15 

Robson T, Joiner MC, Wilson GD, McCullough W, Price ME, Logan I, Jones H, McKeown SR and Hirst DG: A novel human stress response-related gene with a potential role in induced radio-resistance. Radiat Res. 152:451–461. 1999. View Article : Google Scholar : PubMed/NCBI

16 

Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 362:847–849. 1993. View Article : Google Scholar : PubMed/NCBI

17 

Honda M, Kaneko S, Kawai H, Shirota Y and Kobayashi K: Differential gene expression between chronic hepatitis B and C hepatic lesion. Gastroenterology. 120:955–966. 2001. View Article : Google Scholar : PubMed/NCBI

18 

Okabe H, Satoh S, Kato T, Kitahara O, Yanagawa R, Yamaoka Y, Tsunoda T, Furukawa Y and Nakamura Y: Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res. 61:2129–2137. 2001.

19 

Shirota Y, Kaneko S, Honda M, Kawai HF and Kobayshi K: Identification of differently expressed genes in hepatocellular carcinoma with cDNA microarrays. Hepatology. 33:832–840. 2001. View Article : Google Scholar : PubMed/NCBI

20 

Takeo S, Arai H, Kusano N, Harada T, et al: Examination of oncogene amplification by genomic DNA microarray in hepatocellular carcinomas comparison with comparative genomic hybridization analysis. Cancer Genet Cytogenet. 130:127–132. 2001. View Article : Google Scholar

21 

Xu XR, Huang J, Xu ZG, et al: Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Proc Natl Acad Sci USA. 98:15089–15094. 2001. View Article : Google Scholar

22 

Kis E, Szatmari T, Keszei M, Farkas R, Esik O, Lumniczky K, Falus A and Safrany G: Microarray analysis of radiation response genes in primary human fibroblasts. Int J Radiat Oncol Biol Phys. 66:1506–1514. 2006. View Article : Google Scholar : PubMed/NCBI

23 

Hondermarck H, Vercoutter-Edouart A-S, Revillion F, Lemoine J, El-Yazidi-Belkoura I, Nurcombe V and Peyrat JP: Proteomics of breast cancer for marker discovery and signal pathway profiling. Proteomics. 1:1216–1232. 2001. View Article : Google Scholar : PubMed/NCBI

24 

Oh JM, Brichory F, Puravs E, Kuick R, Wood C, Rouillard JM, Tra J, Kardia S, Beer D and Hanash S: A database of protein expression in lung cancer. Proteomics. 1:1303–1319. 2001. View Article : Google Scholar : PubMed/NCBI

25 

Stulik J, Hernychova L, Porkertova S, Knižek J, Macela A, Bures J, Jandik P, Langridge JI and Jungblut PR: Proteome study of colorectal carcinogenesis. Electrophoresis. 22:3019–3025. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Kim W, Oe LS, Kim JS, Ryu YH, Byeon JY, Kim HJ, Kim YI, Heo JS, Park YM and Jung G: Comparison of proteome between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma. Clin Cancer Res. 9:5493–5500. 2003.PubMed/NCBI

27 

Janicke RU, Engels IH, Dunkern T, Kaina B, Schulze-Osthoff K and Porter AG: Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells. Oncogene. 20:5043–5053. 2001. View Article : Google Scholar : PubMed/NCBI

28 

Albala JS, Thelen MP, Prange C, Fan W, Christensen M, Thompson LH and Lennon GG: Identification of a novel human RAD51 homolog, RAD51B. Genomics. 46:476–479. 1997. View Article : Google Scholar : PubMed/NCBI

29 

Jin K, Nagayama T, Chen J, Stetler AR, Kawaguchi K, Simon RP and Graham SH: Molecular cloning of a cell cycle regulation gene cyclin H from ischemic rat brain: expression in neurons after global cerebral ischemia. J Neurochem. 73:1598–1608. 1999. View Article : Google Scholar : PubMed/NCBI

30 

Lee TH, Wisniewski HG and Vilcek J: A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J Cell Biol. 116:545–557. 1992. View Article : Google Scholar

31 

Kaulsay KK, Mertani HC, Tornell J, Morel G, Lee KO and Lobie PE: Autocrine stimulation of human mammary carcinoma cell proliferation by human growth hormone. Exp Cell Res. 250:35–50. 1999. View Article : Google Scholar : PubMed/NCBI

32 

Oliveira-dos-Santos AJ, Matsumoto G, Snow BE, et al: Regulation of T cell activation, anxiety, and male aggression by RGS2. Proc Natl Acad Sci USA. 97:12272–12277. 2000. View Article : Google Scholar : PubMed/NCBI

33 

Pearson AS, Spitz FR, Swisher SG, Kataoka M, Sarkiss MG, Meyn RE, McDonnell TJ, Cristiano RJ and Roth JA: Up- regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells. Clin Cancer Res. 6:887–890. 2000.PubMed/NCBI

34 

Chittenden T, Harrington EA, O’Connor R, Flemington C, Lutz RJ, Evan GI and Guild BC: Induction of apoptosis by the Bcl-2 homologue Bak. Nature. 374:733–736. 1995. View Article : Google Scholar : PubMed/NCBI

35 

Farrow SN, White JH, Martinou I, Raven T, Pun KT, Grinham CJ, Martinou JC and Brown R: Cloning of a bcl-2 homo-logue by interaction with adenovirus E1B 19K. Nature. 374:731–733. 1995. View Article : Google Scholar : PubMed/NCBI

36 

Kiefer MC, Brauer MJ, Powers VC, Wu JJ, Umansky SR, Tomei LD and Barr PJ: Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature. 374:736–739. 1995. View Article : Google Scholar : PubMed/NCBI

37 

Clemmons DR, Camacho-Hubner C, Coronado E and Osborne CK: Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status. Endocrinology. 127:2679–2686. 1990. View Article : Google Scholar : PubMed/NCBI

38 

Pekonen F, Nyman T, Ilvesmöki V and Partanen S: Insulin-like growth factor binding proteins in human breast cancer tissue. Cancer Res. 52:5204–5207. 1992.PubMed/NCBI

39 

Pistritto G, Jost M, Srinivasula SM, Baffa R, Poyet JL, Kari C, Lazebnik Y, Rodeck U and Alnemri ES: Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. Cell Death Differ. 9:995–1006. 2002. View Article : Google Scholar : PubMed/NCBI

40 

Jurianz K, Ziegler S, Garcia-Schüler H, Kraus S, Bohana-Kashtan O, Fishelson Z and Kirschfink M: Complement resistance of tumor cells: basal and induced mechanisms. Mol Immunol. 36:929–939. 1999. View Article : Google Scholar : PubMed/NCBI

41 

Sugimoto M, Nakamura T, Ohtani N, Hampson L, Hampson IN, Shimamoto A, Furuichi Y, Okumura K, Niwa S, Taya Y and Hara E: Regulation of CDK4 activity by a novel CDK4-binding protein, p34 (SEI-1). Genes Dev. 13:3027–3033. 1999. View Article : Google Scholar : PubMed/NCBI

42 

Herbert BR, Sanchez J-C, Bini L, Wilkins MR, Williams KL, Appel RD and Hochstrasser DF: Proteome Research: New Frontiers in Functional Genomics. Springer; Berlin: pp. 13–33. 1997

43 

Sherr CJ and Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501–1512. 1999. View Article : Google Scholar : PubMed/NCBI

44 

Bartek J, Bartkova J and Lukas J: The retinoblastoma protein pathway in cell cycle control and cancer. Exp Cell Res. 237:1–6. 1997. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Jung S, Lee S, Lee J, Li C, Ohk J, Jeong HK, Lee S, Kim S, Choi Y, Kim S, Kim S, et al: Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells. Oncol Lett 3: 147-154, 2012.
APA
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H. ... Lee, M. (2012). Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells. Oncology Letters, 3, 147-154. https://doi.org/10.3892/ol.2011.444
MLA
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H., Lee, S., Kim, S., Choi, Y., Kim, S., Lee, H., Lee, M."Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells". Oncology Letters 3.1 (2012): 147-154.
Chicago
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H., Lee, S., Kim, S., Choi, Y., Kim, S., Lee, H., Lee, M."Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells". Oncology Letters 3, no. 1 (2012): 147-154. https://doi.org/10.3892/ol.2011.444
Copy and paste a formatted citation
x
Spandidos Publications style
Jung S, Lee S, Lee J, Li C, Ohk J, Jeong HK, Lee S, Kim S, Choi Y, Kim S, Kim S, et al: Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells. Oncol Lett 3: 147-154, 2012.
APA
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H. ... Lee, M. (2012). Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells. Oncology Letters, 3, 147-154. https://doi.org/10.3892/ol.2011.444
MLA
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H., Lee, S., Kim, S., Choi, Y., Kim, S., Lee, H., Lee, M."Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells". Oncology Letters 3.1 (2012): 147-154.
Chicago
Jung, S., Lee, S., Lee, J., Li, C., Ohk, J., Jeong, H., Lee, S., Kim, S., Choi, Y., Kim, S., Lee, H., Lee, M."Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells". Oncology Letters 3, no. 1 (2012): 147-154. https://doi.org/10.3892/ol.2011.444
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team