Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February 2012 Volume 3 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February 2012 Volume 3 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography

  • Authors:
    • Ikuko Sakata
    • Yuichi Ozeki
    • Katsumi Tamura
    • Jiro Ishida
    • Shinsuke Aida
    • Yoshiyuki Abe
  • View Affiliations / Copyright

    Affiliations: Tokorozawa PET Diagnostic Imaging Clinic, Tokorozawa, Saitama 359-1124, Japan, Department of Thoracic Surgery, National Defense Medical College, Tokorozawa, Saitama 359-1124, Japan, Department of Diagnostic Pathology, National Defense Medical College, Tokorozawa, Saitama 359-1124, Japan
  • Pages: 297-299
    |
    Published online on: November 22, 2011
       https://doi.org/10.3892/ol.2011.492
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

There has been an increase in the detection rate of small early lung cancer due to recent improvements in imaging technology. However, conventional imaging modalities such as computed tomography (CT) alone are not capable of differentiating small pulmonary nodules. New modalities such as F-18 2'-deoxy-2fluoro-D-glucose (FDG) positron emission tomography combined with CT (PET/CT) have contributed to the evaluation of lung cancer staging, although the differential diagnosis of pulmonary nodules showing ground-glass opacity (GGO) with PET/CT is controversial. In Japan, cancer screening with whole body FDG-PET has been available for asymptomatic individuals, and it has been reported that a wide variety of cancer types are detectable by FDG-PET at potentially curable stages. We present the case of a 62-year-old male with early lung cancer, which was revealed by repeated health screening. A PET/CT scan revealed definite intense FDG uptake (SUVmax 1.2) in the pulmonary nodules of the right upper lobe, while no definite FDG uptake was observed in the lesion in the previous annual screening. Right upper lobectomy was performed, and the pathological diagnosis was well-differentiated adenocarcinoma. Five-year survival has been noted since the thoracotomy, and the patient is doing well without recurrence. This is a significant case of early lung cancer with GGO lesions, which revealed intense FDG uptake during an annual repeated health screening with FDG-PET/CT.
View Figures

Figure 1

Figure 2

View References

1 

Kaneko M, Eguchi K, Ohmatsu H, Kakinuma R, Naruke T, Suemasu K and Moriyama N: Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. Radiology. 201:798–802. 1996. View Article : Google Scholar : PubMed/NCBI

2 

Abe Y, Hanai K, Nakano M, Ohkubo Y, Hashizume T, Kakizaki T, Nakamura M, Niki N, Egichi K, Fujino T and Moriyama N: A computer-aided diagnosis (CAD) system in lung cancer screening with computed tomography. Anticancer Res. 25:483–488. 2005.PubMed/NCBI

3 

Abe Y, Nakamura M, Ozeki Y, Machida K and Ogata T: Lung cancer: Low-dose helical computed tomography. Cancer Imaging: Lung and Breast Carcinoma. 1. Hayat MA: Elsevier; Academic Press; pp. 203–207. 2007

4 

Nakata M, Saeki H, Takata I, Segawa Y, Mogami H, Mandai K and Eguchi K: Focal ground-glass opacity detected by low-dose helical CT. Chest. 121:1464–1467. 2002. View Article : Google Scholar : PubMed/NCBI

5 

Gould MK, Maclean CC, Kuschner WG, Rydzak CE and Owens DK: Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions: a meta-analysis. JAMA. 285:914–924. 2001. View Article : Google Scholar : PubMed/NCBI

6 

Kim SK, Allen-Auerbach M, Goldin J, Fueger BJ, Dahlbom M, Brown M, Czernin J and Schiepers C: Accuracy of PET/CT in characterization of solitary pulmonary lesions. J Nucl Med. 48:214–220. 2007.PubMed/NCBI

7 

Yasuda S and Shohtsu A: Cancer screening with whole-body 18F-fluorodeoxyglucose positron-emission tomography. Lancet. 350:18191997. View Article : Google Scholar : PubMed/NCBI

8 

Yasuda S, Ide M, Fujii H, Nakahara T, Mochizuki Y, Takahashi W and Shohtsu A: Application of positron emission tomography imaging to cancer screening. Br J Cancer. 83:1607–1611. 2000. View Article : Google Scholar : PubMed/NCBI

9 

Ide M: Cancer screening with FDG-PET. Q J Nucl Med Mol Imaging. 50:23–27. 2006.PubMed/NCBI

10 

Cronin CG, Swords R, Truong MT, Viswanathan C, Rohren E, Giles FJ, O’Dwyer M and Bruzzi JF: Clinical utility of PET/CT in lymphoma. AJR Am J Roentgenol. 194:W91–W103. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Ueda S, Saeki T, Tsuda H, Shigekawa T, Omata J, Moriya T, Yamamoto J, Osaki A, Fujiuchi N, Misumi M, et al: 18F-fluorodeoxyglucose positron emission tomography optimizes neoadjuvant chemotherapy for primary breast cancer to achieve pathological complete response. Int J Clin Oncol. 2011.(E-pub ahead of print).

12 

Xie L, Saynak M, Veeramachaneni NK, Fried DV, Jagtap MR, Chiu WK, Higginson DS, Lawrence MV, Khandani AH, Qaqish BF, Chen RC and Marks LB: Non-small cell lung cancer: Prognostic importance of positive FDG PET findings in the mediastinum for patients with N0-1 disease at pathologic analysis. Radiology. 2011.(E-pub ahead of print).

13 

Abe Y, Tamura K, Sakata I, Ishida J, Ozeki Y, Tamura A, Uematsu K, Sakai H, Goya T, Kanazawa M and Machida K: Clinical implications of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) at delayed phase for diagnosis and prognosis of malignant pleural mesothelioma. Oncol Rep. 2011 Oct 24; View Article : Google Scholar : (Epub ahead of print).

14 

Chun EJ, Lee HJ, Kang WJ, Kim KG, Goo JM, Park CM and Lee CH: Differentiation between malignancy and inflammation in pulmonary ground-glass nodules: the feasibility of integrated (18)F-FDG PET/CT. Lung Cancer. 65:180–186. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Fischer B, Lassen U, Mortensen J, Larsen S, Loft A, Bertelsen A, Ravn J, Clementsen P, Høgholm A, Larsen K, et al: Preoperative staging of lung cancer with combined PET-CT. N Engl J Med. 361:32–39. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Cloran FJ, Banks KP, Song WS, Kim and Bradley YC: Limitations of dual time point PET in the assessment of lung nodules with low FDG avidity. Lung Cancer. 68:66–71. 2010. View Article : Google Scholar : PubMed/NCBI

17 

Fischer BM, Lassen U and Højgaard L: PET-CT in preoperative staging of lung cancer. N Engl J Med. 364:980–981. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Abe Y, Tamura K, Sakata I, Ishida J, Fukuba I, Matsuoka R, Shimizu S, Murakami H and Machida K: Usefulness of 18F-FDG positron emission tomography/computed tomography for the diagnosis of pyothorax-associated lymphoma: A report of three cases. Oncol Lett. 1:833–836. 2010.

19 

Henschke CI, Boffetta P, Gorlova O, Yip R, Delancey JO and Foy M: Assessment of lung-cancer mortality reduction from CT screening. Lung Cancer. 71:328–332. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Fleming AJ Jr and Johansen ME: The clinician’s expectations from the use of positron emission tomography/computed tomography scanning in untreated and treated head and neck cancer patients. Curr Opin Otolaryngol Head Neck Surg. 16:127–134. 2008.

21 

Ueda S, Tsuda H, Asakawa H, Shigekawa T, Fukatsu K, Kondo N, Yamamoto M, Hama Y, Tamura K, Ishida J, Abe Y and Mochizuki H: Clinicopathological and prognostic relevance of uptake level using 18F-fluorodeoxyglucose positron emission tomography computed tomography fusion imaging (18F-FDG PET/CT) in primary breast cancer. Jpn J Clin Oncol. 38:250–258. 2008. View Article : Google Scholar

22 

Abe Y, Tamura K, Sakata I, Ishida J, Mukai M, Ohtaki M, Nakamura M and Machida K: Unique intense uptake demonstrated by 18F-FDG positron emission tomography/computed tomography (PET/CT) in primary pancreatic lymphoma: A case report. Oncol Lett. 1:605–607. 2010.PubMed/NCBI

23 

Ozeki Y, Abe Y, Kita H, Tamura K, Sakata I, Ishida J and Machida K: A case of primary lung cancer lesion demonstrated by F-18 FDG positron emission tomography/computed tomography (PET/CT) one year after the detection of metastatic brain tumor. Oncol Lett. 2:621–623. 2011.PubMed/NCBI

24 

Abe Y, Tamura T, Sakata I, Ishida J, Nagata M, Machida K and Ogata T: Lung cancer: Computer-aided diagnosis with computed tomography. Cancer Imaging: Lung and Breast Carcinoma. 1. Hayat MA: Elsevier; Academic Press; pp. 209–214. 2007

25 

Suzuki K, Kusumoto M, Watanabe S, Tsuchiya R and Asamura H: Radiologic classification of small adenocarcinoma of the lung: radiologic-pathologic correlation and its prognostic impact. Ann Thorac Surg. 81:413–419. 2006. View Article : Google Scholar : PubMed/NCBI

26 

Murano T, Minamimoto R, Senda M, Uno K, Jinnouchi S, Fukuda H, Iinuma T, Tsukamoto E, Terauchi T, Yoshida T, et al: Radiation exposure and risk-benefit analysis in cancer screening using FDG-PET: results of a Japanese nationwide survey. Ann Nucl Med. 2011.(E-pub ahead of print).

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Sakata I, Ozeki Y, Tamura K, Ishida J, Aida S and Abe Y: A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography. Oncol Lett 3: 297-299, 2012.
APA
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., & Abe, Y. (2012). A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography. Oncology Letters, 3, 297-299. https://doi.org/10.3892/ol.2011.492
MLA
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., Abe, Y."A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography". Oncology Letters 3.2 (2012): 297-299.
Chicago
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., Abe, Y."A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography". Oncology Letters 3, no. 2 (2012): 297-299. https://doi.org/10.3892/ol.2011.492
Copy and paste a formatted citation
x
Spandidos Publications style
Sakata I, Ozeki Y, Tamura K, Ishida J, Aida S and Abe Y: A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography. Oncol Lett 3: 297-299, 2012.
APA
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., & Abe, Y. (2012). A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography. Oncology Letters, 3, 297-299. https://doi.org/10.3892/ol.2011.492
MLA
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., Abe, Y."A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography". Oncology Letters 3.2 (2012): 297-299.
Chicago
Sakata, I., Ozeki, Y., Tamura, K., Ishida, J., Aida, S., Abe, Y."A case of early stage lung cancer detected by repeated cancer screening with positron emission tomography". Oncology Letters 3, no. 2 (2012): 297-299. https://doi.org/10.3892/ol.2011.492
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team