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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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April 2012 Volume 3 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

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Article

Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis

  • Authors:
    • Yoshinobu Mitsuyama
    • Hiroaki Shiba
    • Koichiro Haruki
    • Yuki Fujiwara
    • Kenei  Furukawa
    • Tomonori Iida
    • Takenori Hayashi
    • Masaichi Ogawa
    • Yuichi  Ishida
    • Takeyuki Misawa
    • Hideyuki Kashiwagi
    • Katsuhiko Yanaga

  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Jikei University School of Medicine, Tokyo 105-8461, Japan
  • Pages: 767-771
    |
    Published online on: January 18, 2012
       https://doi.org/10.3892/ol.2012.574
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Abstract

No evidence currently exists to demonstrate the prognostic value of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) in patients with unresectable colorectal cancer liver metastases (CRLM). Therefore, we retrospectively investigated the correlation between serum CEA and CA19-9 levels and overall survival in patients with unresectable CRLM. The study involved 40 patients who were diagnosed with unresectable CRLM between March 2000 and August 2010 at Jikei University Hospital, Japan. We retrospectively investigated the correlation between patient characteristics, including serum CEA and CA19-9 levels, and overall survival using univariate and multivariate analyses. In the univariate analysis, the absence of primary tumor resection (p=0.0161), the absence of systemic chemotherapy (p=0.0119), serum CEA ≥100 ng/ml (p=0.0148) and CA19-9 ≥100 U/ml (p<0.0001) were significant predictors of poor survival. In the multivariate analysis, the absence of systemic chemotherapy (p=0.0356), serum CEA ≥100 ng/ml (p=0.0079) and CA19-9 ≥100 U/ml (p=0.0002) were independent predictors. Serum CEA and CA19-9 levels are therefore independent prognostic predictors of survival in patients with unresectable CRLM.

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Copy and paste a formatted citation
Spandidos Publications style
Mitsuyama Y, Shiba H, Haruki K, Fujiwara Y, Furukawa K, Iida T, Hayashi T, Ogawa M, Ishida Y, Misawa T, Misawa T, et al: Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. Oncol Lett 3: 767-771, 2012.
APA
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T. ... Yanaga, K. (2012). Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. Oncology Letters, 3, 767-771. https://doi.org/10.3892/ol.2012.574
MLA
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T., Hayashi, T., Ogawa, M., Ishida, Y., Misawa, T., Kashiwagi, H., Yanaga, K."Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis". Oncology Letters 3.4 (2012): 767-771.
Chicago
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T., Hayashi, T., Ogawa, M., Ishida, Y., Misawa, T., Kashiwagi, H., Yanaga, K."Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis". Oncology Letters 3, no. 4 (2012): 767-771. https://doi.org/10.3892/ol.2012.574
Copy and paste a formatted citation
x
Spandidos Publications style
Mitsuyama Y, Shiba H, Haruki K, Fujiwara Y, Furukawa K, Iida T, Hayashi T, Ogawa M, Ishida Y, Misawa T, Misawa T, et al: Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. Oncol Lett 3: 767-771, 2012.
APA
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T. ... Yanaga, K. (2012). Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. Oncology Letters, 3, 767-771. https://doi.org/10.3892/ol.2012.574
MLA
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T., Hayashi, T., Ogawa, M., Ishida, Y., Misawa, T., Kashiwagi, H., Yanaga, K."Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis". Oncology Letters 3.4 (2012): 767-771.
Chicago
Mitsuyama, Y., Shiba, H., Haruki, K., Fujiwara, Y., Furukawa, K., Iida, T., Hayashi, T., Ogawa, M., Ishida, Y., Misawa, T., Kashiwagi, H., Yanaga, K."Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis". Oncology Letters 3, no. 4 (2012): 767-771. https://doi.org/10.3892/ol.2012.574
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