Locally metastatic mucinous rectal adenocarcinoma: Imaging diagnosis with DW-MRI in comparison with PET-CT

Bozkurt,Mustafa; Okutur,Kerem; Aydın,Kübra; Namal,Esat; Öztürk,Akın; Balcı,Cem; Demir,Gökhan

doi:10.3892/ol.2012.663

June 2012 Volume 3 Issue 6

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June 2012 Volume 3 Issue 6

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Article

Locally metastatic mucinous rectal adenocarcinoma: Imaging diagnosis with DW-MRI in comparison with PET-CT

Authors:
- Mustafa Bozkurt
- Kerem Okutur
- Kübra Aydın
- Esat Namal
- Akın Öztürk
- Cem Balcı
- Gökhan Demir
View Affiliations / Copyright

Affiliations: Department of Medical Oncology, Istanbul Bilim University School of Medicine, Istanbul, Turkey, Department of Radiology, Istanbul Bilim University School of Medicine, Istanbul, Turkey
Pages: 1311-1313
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Published online on: March 29, 2012

https://doi.org/10.3892/ol.2012.663
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Abstract

A 56-year-old male patient with locally advanced mucinous rectal cancer underwent neoadjuvant chemoradiotherapy. Follow-up imaging with positron emission tomography‑computed tomography (PET‑CT) revealed a local response to chemoradiotherapy, whereas diffusion-weighted magnetic resonance imaging (DW‑MRI) showed newly presented sacral bone metastasis. Histopathologically confirmed bone metastasis and the local tumor were surgically removed. Repeat DW‑MRI revealed tumor recurrence in the sacral excision zone eight months after surgery, which was reconfirmed by histopathology. This case shows the superior imaging ability of DW‑MRI in the diagnosis of mucinous tumors in comparison to PET-CT.

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1	Koyama T, Tamai K and Togashi K: Current status of body MR imaging: fast MR imaging and diffusion-weighted imaging. Int J Clin Oncol. 11:278–285. 2006. View Article : Google Scholar : PubMed/NCBI
2	Kwee TC, Takahara T, Ochiai R, et al: Complementary roles of whole-body diffusion-weighted MRI and 18F-FDG PET: the state of the art and potential applications. J Nucl Med. 51:1549–1558. 2010. View Article : Google Scholar : PubMed/NCBI
3	Watanabe T: Chemoradiotherapy and adjuvant chemotherapy for rectal cancer. Int J Clin Oncol. 13:488–497. 2008. View Article : Google Scholar : PubMed/NCBI
4	Eschmann SM, Pfannenberg AC, Rieger A, et al: Comparison of 11C choline- PET/CT and whole body-MRI for staging of prostate cancer. Nuklearmedizin. 46:161–168. 2007.PubMed/NCBI
5	Kim SH, Lee JM, Hong SH, et al: Locally advanced rectal cancer: added value of diffusion-weighted MR imaging in the evaluation of tumor response to neoadjuvant chemo- and radiation therapy. Radiology. 253:116–125. 2009. View Article : Google Scholar : PubMed/NCBI
6	Endo K, Oriuchi N, Higuchi T, et al: PET and PET/CT using 18F-FDG in the diagnosis and management of cancer patients. Int J Clin Oncol. 11:286–296. 2006. View Article : Google Scholar : PubMed/NCBI
7	Dresen RC, Beets GL, Rutten HJ, et al: Locally advanced rectal cancer: MR imaging for restaging after neoadjuvant radiation therapy with concomitant chemotherapy. Part I Are we able to predict tumor confined to the rectal wall? Radiology. 252:71–80. 2009. View Article : Google Scholar
8	Mainenti PP, Iodice D, Segreto S, et al: Colorectal cancer and 18FDG-PET/CT: what about adding the T to the N parameter in loco-regional staging? World J Gastroenterol. 17:1427–1433. 2011. View Article : Google Scholar : PubMed/NCBI
9	Hur H, Kim NK, Yun M, et al: ¹⁸Fluoro-deoxy-glucose positron emission tomography in assessing tumor response to preoperative chemoradiation therapy for locally advanced rectal cancer. J Surg Oncol. 103:17–24. 2011. View Article : Google Scholar
10	Zhu A, Lee D and Shim H: Metabolic positron emission tomography imaging in cancer detection and therapy response. Semin Oncol. 38:55–69. 2011. View Article : Google Scholar : PubMed/NCBI
11	Connelly JH, Robey-Cafferty SS and Cleary KB: Mucinous carcinomas of the colon and rectum: analysis of 62 stage B and C lesions. Arch Pathol Lab Med. 115:1022–1025. 1991.PubMed/NCBI
12	Berger KL, Nicholson SA, Dehdashti F and Siegel BA: FDG PET evaluation of mucinous neoplasms: correlation of FDG uptake with histopathologic features. Am J Roentgenol. 174:1005–1008. 2000. View Article : Google Scholar : PubMed/NCBI
13	Green JB, Timmcke AE, Mitchell WT, Hicks TC, Gathright JB Jr and Ray JE: Mucinous carcinoma-just another colon cancer? Dis Colon Rectum. 36:49–54. 1993. View Article : Google Scholar : PubMed/NCBI
14	Kim DJ, Kim JH, Lim JS, et al: Restaging of rectal cancer with MR imaging after concurrent chemotherapy and radiation therapy. Radiographics. 30:503–516. 2010. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Locally metastatic mucinous rectal adenocarcinoma: Imaging diagnosis with DW-MRI in comparison with PET-CT

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