Gastric carcinosarcoma: A case report and review of the literature

  • Authors:
    • Roberto Cirocchi
    • Stefano Trastulli
    • Jacopo Desiderio
    • Veronica  Grassi
    • Ivan Barillaro
    • Alberto Santoro
    • Carlo  Boselli
    • Nicola  Avenia
    • Giuseppe Noya
    • Angelo De Sol
  • View Affiliations

  • Published online on: April 27, 2012     https://doi.org/10.3892/ol.2012.699
  • Pages: 53-58
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Abstract

Carcinosarcoma of the stomach is a rare biphasic tumor that consists of both carcinomatous and sarcomatous components. The common carcinoma component is tubular or papillary adenocarcinoma and the mesenchymal sarcomatous components are variable but may include leiomyosarcoma, rhabdomyosarcoma and osteosarcoma. The aim of this study was to describe the characteristics of gastric carcinosarcoma and to present a review of the available literature. We report a case of carcinosarcoma in a 62-year-old female including the clinical and histopathological features of this tumor. Following ultrasound and computed tomography scans, laparotomy was performed, revealing a large mass, followed by radical surgery. Macroscopically, a polypoid tumor was observed. Microscopically, the tumor was composed of moderately differentiated adenocarcinoma and poorly differentiated sarcoma with a high mitotic index and necrotic areas. At present, the achievement of a definitive diagnosis is dependent on immunohistochemical staining and radical surgery. Thus, more effective diagnostic methods are required to improve patient survival.
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July 2012
Volume 4 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Cirocchi R, Trastulli S, Desiderio J, Grassi V, Barillaro I, Santoro A, Boselli C, Avenia N, Noya G, De Sol A, De Sol A, et al: Gastric carcinosarcoma: A case report and review of the literature. Oncol Lett 4: 53-58, 2012
APA
Cirocchi, R., Trastulli, S., Desiderio, J., Grassi, V., Barillaro, I., Santoro, A. ... De Sol, A. (2012). Gastric carcinosarcoma: A case report and review of the literature. Oncology Letters, 4, 53-58. https://doi.org/10.3892/ol.2012.699
MLA
Cirocchi, R., Trastulli, S., Desiderio, J., Grassi, V., Barillaro, I., Santoro, A., Boselli, C., Avenia, N., Noya, G., De Sol, A."Gastric carcinosarcoma: A case report and review of the literature". Oncology Letters 4.1 (2012): 53-58.
Chicago
Cirocchi, R., Trastulli, S., Desiderio, J., Grassi, V., Barillaro, I., Santoro, A., Boselli, C., Avenia, N., Noya, G., De Sol, A."Gastric carcinosarcoma: A case report and review of the literature". Oncology Letters 4, no. 1 (2012): 53-58. https://doi.org/10.3892/ol.2012.699