Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
July 2012 Volume 4 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July 2012 Volume 4 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature

  • Authors:
    • Weigang Ren
    • Zhaohui Zhong
    • Xiaokun Zhao
    • Junjie Yang
    • Lei Zhang
    • Ran Xu
    • Songchao Li
    • Xuan Zhu
    • Chen Lu
    • Joseph L. Chin
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Urology, Shanghai Changhai Hospital, Shanghai 200433, P.R. China, Department of Urology and Oncology, University of Western Ontario, London, Ontario N6A 4V2, Canada
  • Pages: 59-62
    |
    Published online on: April 30, 2012
       https://doi.org/10.3892/ol.2012.701
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Primary testicular non-Hodgkin's lymphoma (TNHL) was first described as a clinical entity in 1866. It is a rare disease which accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. Hemophagocytic syndrome (HPS) is a rare but distinct condition caused by inappropriate and dysregulated activation of the immune system. We report a 47-year-old man with primary TNHL who developed HPS four months after occurrence of scrotal swelling. To the best of our knowledge, primary TNHL associated with HPS has not previously been reported.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Shahab N and Doll DC: Testicular lymphoma. Semin Oncol. 26:259–269. 1999.

2 

Ballen KK and Hasserjian RP: Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises Case 15-2004 A 31-year-old man with bilateral testicular enlargement. N Engl J Med. 350:2081–2087. 2004.

3 

Touroutoglou N, Dimopoulos MA, Younes A, et al: Testicular lymphoma: late relapses and poor outcome despite doxorubicin-based therapy. J Clin Oncol. 13:1361–1367. 1995.PubMed/NCBI

4 

Eskey CJ, Whitman GJ and Chew FS: Malignant lymphoma of the testis. AJR Am J Roentgenol. 169:8221997. View Article : Google Scholar : PubMed/NCBI

5 

Buskirk SJ, Evans RG, Banks PM, et al: Primary lymphoma of the testis. Int J Radiat Oncol Biol Phys. 8:1699–1703. 1982. View Article : Google Scholar : PubMed/NCBI

6 

Lobo FD, Bansal R, Naik R, et al: Primary testicular lymphoma. J Indian Med Assoc. 96:193–194. 1998.

7 

Sussman EB, Hajdu SI, Lieberman PH and Whitmore WF: Malignant lymphoma of the testis: a clinicopathologic study of 37 cases. J Urol. 118:1004–1007. 1977.PubMed/NCBI

8 

Rouphael NG, Talati NJ, Vaughan C, et al: Infections associated with haemophagocytic syndrome. Lancet Infect Dis. 7:814–822. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Janka GE: Familial and acquired hemophagocytic lymphohistocytosis. Eur J Pediatr. 166:95–109. 2007. View Article : Google Scholar : PubMed/NCBI

10 

Lagrange JL, Ramaioli A, Theodore CH, et al: Non-Hodgkin’s lymphoma of the testis: a retrospective study of 84 patients treated in the French anticancer centres. Ann Oncol. 12:1313–1319. 2001.

11 

Tepperman BS, Gospodarowicz MK, Bush RS and Brown TC: Non-Hodgkin lymphoma of the testis. Radiology. 142:203–208. 1982. View Article : Google Scholar : PubMed/NCBI

12 

Moller MB, D’Amore F and Christensen BE: Testicular lymphoma: a population-based study of incidence, clinicopathological correlations and prognosis. The Danish Lymphoma Study Group, LYFO. Eur J Cancer. 30A:1760–1764. 1994. View Article : Google Scholar

13 

Ko Y, Cho E-Y, Kim J-E, et al: NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status. Histopathology. 44:480–489. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Chan J, Sin V, Wong K, et al: Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood. 89:4501–4513. 1997.PubMed/NCBI

15 

Cheung MM, Chan JK, Lau WH, et al: Primary non-Hodgkin’s lymphoma of the nose and nasopharynx: clinical features, tumor immunophenotype, and treatment outcome in 113 patients. J Clin Oncol. 16:70–77. 1998.

16 

Falini B, Pileri S, De Solas I, et al: Peripheral T-cell lymphoma associated with hemophagocytic syndrome. Blood. 75:434–444. 1990.PubMed/NCBI

17 

Ornstein DL, Bifulco CB, Braddock DT and Howe JG: Histopathologic and molecular aspects of CD56+ natural killer/T-cell lymphoma of the testis. Int J Surg Pathol. 16:291–300. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Janka GE: Hemophagocytic syndromes. Blood Rev. 21:245–253. 2007. View Article : Google Scholar : PubMed/NCBI

19 

Han AR, Lee HR, Park BB, et al: Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome. Ann Hematol. 86:493–498. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Fardet L, Blum L, Kerob D, et al: HHV-8 associated hemophagocytic lymphohistiocytosis in HIV-infected patients. Clin Infect Dis. 37:285–291. 2003. View Article : Google Scholar : PubMed/NCBI

21 

Chuang HC, Lay JD, Chuang SE, et al: EBV latent membrane protein-1 down-regulates TNF-[alpha] receptor-1 and confers resistance to TNF-[alpha]-induced apoptosis in T cells: implication for the progression to T-cell lymphoma in EBV-associated hemophagocytic syndrome. Am J Pathol. 170:1607–1617. 2007.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Ren W, Zhong Z, Zhao X, Yang J, Zhang L, Xu R, Li S, Zhu X, Lu C, Chin JL, Chin JL, et al: Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature. Oncol Lett 4: 59-62, 2012.
APA
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R. ... Chin, J.L. (2012). Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature. Oncology Letters, 4, 59-62. https://doi.org/10.3892/ol.2012.701
MLA
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R., Li, S., Zhu, X., Lu, C., Chin, J. L."Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature". Oncology Letters 4.1 (2012): 59-62.
Chicago
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R., Li, S., Zhu, X., Lu, C., Chin, J. L."Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature". Oncology Letters 4, no. 1 (2012): 59-62. https://doi.org/10.3892/ol.2012.701
Copy and paste a formatted citation
x
Spandidos Publications style
Ren W, Zhong Z, Zhao X, Yang J, Zhang L, Xu R, Li S, Zhu X, Lu C, Chin JL, Chin JL, et al: Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature. Oncol Lett 4: 59-62, 2012.
APA
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R. ... Chin, J.L. (2012). Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature. Oncology Letters, 4, 59-62. https://doi.org/10.3892/ol.2012.701
MLA
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R., Li, S., Zhu, X., Lu, C., Chin, J. L."Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature". Oncology Letters 4.1 (2012): 59-62.
Chicago
Ren, W., Zhong, Z., Zhao, X., Yang, J., Zhang, L., Xu, R., Li, S., Zhu, X., Lu, C., Chin, J. L."Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature". Oncology Letters 4, no. 1 (2012): 59-62. https://doi.org/10.3892/ol.2012.701
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team