Gastric adenocarcinoma with thyroid metastasis: A case study and literature review

Feng,Xinglai; Sheng,Liming

doi:10.3892/ol.2013.1206

May 2013 Volume 5 Issue 5

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May 2013 Volume 5 Issue 5

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Article

Gastric adenocarcinoma with thyroid metastasis: A case study and literature review

Authors:
- Xinglai Feng
- Liming Sheng
View Affiliations / Copyright

Affiliations: Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, P.R. China
Pages: 1653-1655
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Published online on: February 22, 2013

https://doi.org/10.3892/ol.2013.1206
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Abstract

Previously, cases of metastatic thyroid cancer were only identified following mortality, by autopsy studies. Incidence of this disease is currently estimated to be between 0.5% in all malignant tumors and 24% in all patients based on autopsy studies. Metastatic thyroid cancer is associated with poor prognosis. In the present study, a 58-year-old male presented with a cervical mass. Subtotal gastrectomy and D2 lymph node dissection identified a poorly differentiated gastric adenocarcinoma. Following this, fine needle aspiration was performed, revealing that the thyroid tumor cells were similar to gastric tumor cells, indicative of metastasis from this organ of origin. In addition, immunohistochemical analysis was consistent with this diagnosis. Palliative radiotherapy of the thyroid mass was performed. At manuscript submission, the patient remained alive.

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1	Kochi M, Fujii M, Kanamori N, Kaiga T, Okubo R, Hagiwara K, et al: Irinotecan plus S-1 for liver metastases of gastric cancer. Hepatogastroenterology. 56:1755–1759. 2009.PubMed/NCBI
2	Mizoshita T, Kataoka H, Kubota E, Okamoto Y, Shimura T, Mori Y, et al: Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil. Int J Clin Oncol. 13:373–376. 2008. View Article : Google Scholar : PubMed/NCBI
3	Yoshida K, Ninomiya M, Takakura N, Hirabayashi N, Takiyama W, Sato Y, et al: Phase II study of docetaxel and S-1 combination therapy for advanced or recurrent gastric cancer. Clin Cancer Res. 12:3402–3407. 2006. View Article : Google Scholar : PubMed/NCBI
4	Nakhjavani MK, Gharib H, Goellner JR and van Heerden JA: Metastasis to the thyroid gland. A report of 43 cases. Cancer. 79:574–578. 1997. View Article : Google Scholar : PubMed/NCBI
5	Chen H, Nicol TL and Udelsman R: Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg. 23:177–180. 1999.discussion 181.
6	Cichoń S, Anielski R, Konturek A, Barczyński M and Cichoń W: Metastases to the thyroid gland: seventeen cases operated on in a single clinical center. Langenbecks Arch Surg. 391:581–587. 2006.PubMed/NCBI
7	Kim TY, Kim WB, Gong G, Hong SJ and Shong YK: Metastasis to the thyroid diagnosed by fine-needle aspiration biopsy. Clin Endocrinol. 62:236–241. 2005. View Article : Google Scholar : PubMed/NCBI
8	Lee HC, Chen FF, Lo CC, Wang CJ, Lo WC and Luh SP: Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature. J Zhejiang Univ Sci B. 11:542–546. 2010. View Article : Google Scholar : PubMed/NCBI
9	Ihn MH, Kim YJ, Kim JJ, Cho JY and Jin SY: A case of thyroid metastasis originating from early gastric cancer. J Korean Med Sci. 24:1230–1233. 2009. View Article : Google Scholar : PubMed/NCBI
10	Ok E and Sözüer E: Thyroid metastasis from gastric carcinoma: report of a case. Surg Today. 30:1005–1007. 2000. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Gastric adenocarcinoma with thyroid metastasis: A case study and literature review

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Abstract

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