Squamous cell carcinoma of the external auditory canal: A case report and review of the literature

Visnyei,Koppany; Gill,Rupinder; Azizi,Efat; Culliney,Bruce

doi:10.3892/ol.2013.1241

Squamous cell carcinoma of the external auditory canal: A case report and review of the literature

Authors:
- Koppany Visnyei
- Rupinder Gill
- Efat Azizi
- Bruce Culliney
View Affiliations

Affiliations: Department of Internal Medicine, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 1003, USA, Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 1003, USA, Division of Hematology Oncology, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 1003, USA
Published online on: March 8, 2013 https://doi.org/10.3892/ol.2013.1241
Pages: 1587-1590

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Squamous cell carcinoma of the external auditory canal, middle ear and temporal bone is a rare and unusual malignancy. The lack of a unifying classification system in the past, along with the rarity of the disease has made the development of clear treatment guidelines difficult. In this report, we describe a clinical case of a patient with this rare malignancy, discuss the challenges associated with the diagnosis and treatment of the disease, and review the literature for trends while outlining the most beneficial treatment strategy for this patient population.

View Figures

View References

1	Lobo D, Llorente JL and Suarez C: Squamous cell carcinoma of the external auditory canal. Skull Base. 18:167–172. 2008. View Article : Google Scholar : PubMed/NCBI
2	Kuhel WI, Hume CR and Selesnick SH: Cancer of the external auditory canal and temporal bone. Otolaryngol Clin North Am. 29:827–852. 1996.PubMed/NCBI
3	Gidley PW: Managing malignancies of the external auditory canal. Expert Rev Anticancer Ther. 9:1277–1282. 2009. View Article : Google Scholar : PubMed/NCBI
4	Ueda Y, Kurita T, Matsuda Y, et al: Superselective, intra-arterial, rapid infusion chemotherapy for external auditory canal carcinoma. J Laryngol Otol. 123(Suppl 31): 75–80. 2009. View Article : Google Scholar : PubMed/NCBI
5	Budrukkar A, Bahl G, Bhalavat R, et al: High-dose-rate brachytherapy boost for carcinoma of external auditory canal. Brachytherapy. 8:392–395. 2009. View Article : Google Scholar : PubMed/NCBI
6	Prabhu R, Hinerman RW, Indelicato DJ, et al: Squamous cell carcinoma of the external auditory canal: long-term clinical outcomes using surgery and external-beam radiotherapy. Am J Clin Oncol. 32:401–404. 2009. View Article : Google Scholar : PubMed/NCBI
7	Arriaga M, Curtin H, Takahashi H, et al: Staging proposal for external auditory meatus carcinoma based on preoperative clinical examination and computed tomography findings. Ann Otol Rhinol Laryngol. 99:714–721. 1990. View Article : Google Scholar
8	Corry J, Peters LJ, Costa ID, et al: The ‘QUAD SHOT’ - a phase II study of palliative radiotherapy for incurable head and neck cancer. Radiother Oncol. 77:137–142. 2005.
9	Moody SA, Hirsch BE and Myers EN: Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system. Am J Otol. 21:582–588. 2000.PubMed/NCBI
10	Austin JR, Stewart KL and Fawzi N: Squamous cell carcinoma of the external auditory canal. Therapeutic prognosis based on a proposed staging system. Arch Otolaryngol Head Neck Surg. 120:1228–1232. 1994. View Article : Google Scholar : PubMed/NCBI
11	Moffat DA, Wagstaff SA and Hardy DG: The outcome of radical surgery and postoperative radiotherapy for squamous carcinoma of the temporal bone. Laryngoscope. 115:341–347. 2005. View Article : Google Scholar : PubMed/NCBI
12	Kollert M, Draf W, Minovi A, et al: [Carcinoma of the external auditory canal and middle ear: therapeutic strategy and follow up]. Laryngorhinootologie. 83:818–823. 2004.(In German).
13	Prasad S and Janecka IP: Efficacy of surgical treatments for squamous cell carcinoma of the temporal bone: a literature review. Otolaryngol Head Neck Surg. 110:270–280. 1994. View Article : Google Scholar : PubMed/NCBI
14	Ogawa K, Nakamura K, Hatano K, et al: Treatment and prognosis of squamous cell carcinoma of the external auditory canal and middle ear: a multi-institutional retrospective review of 87 patients. Int J Radiat Oncol Biol Phys. 68:1326–1334. 2007. View Article : Google Scholar : PubMed/NCBI
15	Nakagawa T, Kumamoto Y, Natori Y, et al: Squamous cell carcinoma of the external auditory canal and middle ear: an operation combined with preoperative chemoradiotherapy and a free surgical margin. Otol Neurotol. 27:242–248. 2006. View Article : Google Scholar : PubMed/NCBI
16	Pfreundner L, Schwager K, Willner J, et al: Carcinoma of the external auditory canal and middle ear. Int J Radiat Oncol Biol Phys. 44:777–788. 1999. View Article : Google Scholar : PubMed/NCBI
17	Yin M, Ishikawa K, Honda K, et al: Analysis of 95 cases of squamous cell carcinoma of the external and middle ear. Auris Nasus Larynx. 33:251–257. 2006. View Article : Google Scholar : PubMed/NCBI
18	Shimatani Y, Kodani K, Mishima K, et al: Evaluation of the results of radiotherapy for carcinoma involving the external auditory canal or middle ear. Nihon Igaku Hoshasen Gakkai Zasshi. 62:739–743. 2002.(In Japanese).
19	Moffat DA and Wagstaff SA: Squamous cell carcinoma of the temporal bone. Curr Opin Otolaryngol Head Neck Surg. 11:107–111. 2003. View Article : Google Scholar : PubMed/NCBI