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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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July 2013 Volume 6 Issue 1

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Case Report

Ewing's sarcoma with an uncommon clinical course: A case report

  • Authors:
    • Rui Niimi
    • Akihiko Matsumine
    • Tomiki Nakamura
    • Ryo Morimoto
    • Tetsuya Murata
    • Takashi  Suzuki
    • Yasuaki Nakashima
    • Takayuki  Nojima
    • Atsumasa Uchida
    • Akihiro Sudo
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Mie 514-8507, Japan, Department of Pathology JA Suzuka General Hospital, Suzuka, Mie 513-8630, Japan, School of Pharmacy, Nihon University, Chiba 274-8555, Japan, Laboratory of Anatomic Pathology, Kyoto University Hospital, Sakyo-ku, Kyoto 606-8507, Japan, Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan
  • Pages: 9-12
    |
    Published online on: April 26, 2013
       https://doi.org/10.3892/ol.2013.1320
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Abstract

Here, a case of Ewing's sarcoma family of tumors (ESFT) of the femur with an unusual clinical course is reported. At 20 years of age, the patient had undergone curettage of a bone tumor of the right femur which was diagnosed as ESFT. One cycle of chemotherapy with vincristine and cyclophosphamide and radiotherapy for a total dose of 40 Gy was administered. The patient did not develop any recurrence or metastases for the following 18 years, in spite of the inadequacy of the initial treatment. At 38 years of age, he was referred to our institution with right thigh pain that had persisted for several months. Radiographs and magnetic resonance imaging findings showed a mass lesion in his proximal femur extending to the soft tissue. An open biopsy was performed and the lesion was diagnosed as recurrence of ESFT, although a molecular biological investigation did not reveal any expression of the characteristic fusion genes that have previously been reported. The patient received standard multimodal therapy employing standard combination chemotherapy for ESFT and wide surgical excision. The patient has been disease-free for 9 years since the treatment. This patient may have a rare subtype of ESFT with an unknown chromosomal translocation and relatively non-aggressive biological behavior.
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Copy and paste a formatted citation
Spandidos Publications style
Niimi R, Matsumine A, Nakamura T, Morimoto R, Murata T, Suzuki T, Nakashima Y, Nojima T, Uchida A, Sudo A, Sudo A, et al: Ewing's sarcoma with an uncommon clinical course: A case report. Oncol Lett 6: 9-12, 2013.
APA
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T. ... Sudo, A. (2013). Ewing's sarcoma with an uncommon clinical course: A case report. Oncology Letters, 6, 9-12. https://doi.org/10.3892/ol.2013.1320
MLA
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T., Nakashima, Y., Nojima, T., Uchida, A., Sudo, A."Ewing's sarcoma with an uncommon clinical course: A case report". Oncology Letters 6.1 (2013): 9-12.
Chicago
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T., Nakashima, Y., Nojima, T., Uchida, A., Sudo, A."Ewing's sarcoma with an uncommon clinical course: A case report". Oncology Letters 6, no. 1 (2013): 9-12. https://doi.org/10.3892/ol.2013.1320
Copy and paste a formatted citation
x
Spandidos Publications style
Niimi R, Matsumine A, Nakamura T, Morimoto R, Murata T, Suzuki T, Nakashima Y, Nojima T, Uchida A, Sudo A, Sudo A, et al: Ewing's sarcoma with an uncommon clinical course: A case report. Oncol Lett 6: 9-12, 2013.
APA
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T. ... Sudo, A. (2013). Ewing's sarcoma with an uncommon clinical course: A case report. Oncology Letters, 6, 9-12. https://doi.org/10.3892/ol.2013.1320
MLA
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T., Nakashima, Y., Nojima, T., Uchida, A., Sudo, A."Ewing's sarcoma with an uncommon clinical course: A case report". Oncology Letters 6.1 (2013): 9-12.
Chicago
Niimi, R., Matsumine, A., Nakamura, T., Morimoto, R., Murata, T., Suzuki, T., Nakashima, Y., Nojima, T., Uchida, A., Sudo, A."Ewing's sarcoma with an uncommon clinical course: A case report". Oncology Letters 6, no. 1 (2013): 9-12. https://doi.org/10.3892/ol.2013.1320
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