Pre‑operative embolization facilitating a posterior approach for the surgical resection of giant sacral neurogenic tumors

Chen,Kangwu; Zhou,Ming; Yang,Huilin; Qian,Zhonglai; Wang,Genlin; Wu,Guizhong; Zhu,Xiaoyu; Sun,Zhiyong

doi:10.3892/ol.2013.1328

July 2013 Volume 6 Issue 1

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July 2013 Volume 6 Issue 1

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Article

Pre‑operative embolization facilitating a posterior approach for the surgical resection of giant sacral neurogenic tumors

Authors:
- Kangwu Chen
- Ming Zhou
- Huilin Yang
- Zhonglai Qian
- Genlin Wang
- Guizhong Wu
- Xiaoyu Zhu
- Zhiyong Sun
View Affiliations / Copyright

Affiliations: Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China
Pages: 251-255
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Published online on: May 8, 2013

https://doi.org/10.3892/ol.2013.1328
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Abstract

The present study aimed to assess a posterior approach for the surgical resection of giant sacral neurogenic tumors, and to evaluate the oncological and functional outcomes. A total of 16 patients with giant sacral neurogenic tumors underwent pre‑operative embolization and subsequent posterior sacral resection between January 2000 and June 2010. Benign tumors were identified in 12 cases, while four cases exhibited malignant peripheral nerve sheath tumors (MPNSTs). An evaluation of the operative techniques used, the level of blood loss, any complications and the functional and oncological outcomes was performed. All tumor masses were removed completely without intra‑operative shock or fatalities. The mean tumor size was 17.5 cm (range, 11.5‑28 cm) at the greatest diameter. The average level of intra‑operative blood loss was 1,293 ml (range, 400‑4,500 ml). Wound complications occurred in four patients (25%), including three cases of cutaneous necrosis and one wound infection. The mean follow‑up time was 59 months (range, 24‑110 months). Tumor recurrence or patient mortality as a result of the disease did not occur in any of the patients with benign sacral neurogenic tumors. The survival rate of the patients with malignant lesions was 75% (3/4 patients) since 25 % (1/4 patients) had multiple local recurrences and succumbed to the disease. The patients with benign tumors scored an average of 92.8% on the Musculoskeletal Tumor Society (MSTS) score functional evaluation, while the patients with malignant tumors scored an average of 60.3%. A posterior approach for the surgical resection of giant sacral neurogenic tumors, combined with pre‑operative embolization may be safely conducted with satisfactory oncological and functional outcomes.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Pre‑operative embolization facilitating a posterior approach for the surgical resection of giant sacral neurogenic tumors

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Abstract

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