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October 2013 Volume 6 Issue 4

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Article

Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy

  • Authors:
    • Yantao Cai
    • Yiming Zhou
    • Zhenyang Li
    • Jianbin Xiang
    • Zongyou Chen
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, P.R. China
  • Pages: 1057-1062
    |
    Published online on: August 2, 2013
       https://doi.org/10.3892/ol.2013.1508
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Abstract

The aim of the present study was to assess the short‑term outcome and survival time of 166 obese patients who received laparoscopic and open colectomy for colorectal cancer (CRC) between January 2007 and December 2012. All 166 patients included in the study had a BMI >28. Laparoscopic or open colectomy procedures were performed on 64 and 102 patients, respectively. The short‑term outcome and post‑operative survival rates were compared. The patient characteristics were similar between the two groups. Laparoscopic colectomy correlated with an increased duration of surgery compared with open colectomy (183 vs. 167 min, respectively; P<0.05) but intraoperative blood loss was decreased (168 vs. 188 ml, respectively; P<0.05). Hospitalization costs were slightly higher following the laparoscopic procedure compared with open surgery, but this was affordable for the majority of patients (¥56,484 vs. ¥56,161, respectively; P<0.05). The incidence of wound infection (17 vs. 31%; P<0.05) and abdominal abscess rates (6 vs. 18%; P<0.05) were reduced in the laparoscopic group compared with the open group. Pathological characteristics were identified to be similar and no significant differences were identified in overall (log‑rank test; P=0.85) and disease‑free (log‑rank test; P=0.85) survival between the two types of surgery (log‑rank test; P=0.76). The current retrospective study demonstrated an improved short‑term outcome in laparoscopic colectomy for CRC patients with a BMI >28 compared with patients who underwent the open procedure. Laparoscopic colectomy is technically and oncologically safe and must be popularized in obese CRC patients.
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1 

No authors listed. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 894:1–253. 2000.PubMed/NCBI

2 

Wang Y, Mi J, Shan XY, et al: Is China facing an obesity epidemic and the consequences? The trends in obesity and chronic disease in China. Int J Obes (Lond). 31:177–188. 2007. View Article : Google Scholar : PubMed/NCBI

3 

Patel SS, Patel MS, Mahanti S, et al: Laparoscopic versus open colon resections in California: a cross-sectional analysis. Am Surg. 78:1063–1065. 2012.PubMed/NCBI

4 

Gendall KA, Raniga S, Kennedy R and Frizelle FA: The impact of obesity on outcome after major colorectal surgery. Dis Colon Rectum. 50:2223–2237. 2007. View Article : Google Scholar : PubMed/NCBI

5 

Singh A, Muthukumarasamy G, Pawa N, et al: Laparoscopic colorectal cancer surgery in obese patients. Colorectal Dis. 13:878–883. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Lascano CA, Kaidar-Person O, Szomstein S, et al: Challenges of laparoscopic colectomy in the obese patient: a review. Am J Surg. 192:357–365. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Khan JS, Hemandas AK, Flashman KG, et al: Clinical outcome of laparoscopic and open colectomy for right colonic carcinoma. Ann R Coll Surg Engl. 93:603–607. 2011. View Article : Google Scholar : PubMed/NCBI

8 

Leroy J, Ananian P, Rubino F, et al: The impact of obesity on technical feasibility and postoperative outcomes of laparoscopic left colectomy. Ann Surg. 241:69–76. 2005.PubMed/NCBI

9 

Gervaz P, Pikarsky A, Utech M, et al: Converted laparoscopic colorectal surgery. Surg Endosc. 15:827–832. 2001. View Article : Google Scholar : PubMed/NCBI

10 

WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 363:157–163. 2004. View Article : Google Scholar : PubMed/NCBI

11 

Zheng W, McLerran DF, Rolland B, et al: Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med. 364:719–729. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Khoury W, Kiran RP, Jessie T, et al: Is the laparoscopic approach to colectomy safe for the morbidly obese? Surg Endosc. 24:1336–1340. 2010. View Article : Google Scholar : PubMed/NCBI

13 

Law WL, Poon JTC, Fan JKM and Lo OS: Survival following laparoscopic versus open resection for colorectal cancer. Int J Colorectal Dis. 27:1077–1085. 2012. View Article : Google Scholar : PubMed/NCBI

14 

Balentine CJ, Marshall C, Robinson C, et al: Obese patients benefit from minimally invasive colorectal cancer surgery. J Surg Res. 163:29–34. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Hotta T, Takifuji K, Yokoyama S, et al: The impact of obesity on learning laparoscopic surgery for colon cancer. J Laparoendosc Adv Surg Tech A. 22:635–640. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Poulsen M and Ovesen H: Is laparoscopic colorectal cancer surgery in obese patients associated with an increased risk? Short-term results from a single center study of 425 patients. J Gastrointest Surg. 16:1554–1558. 2012. View Article : Google Scholar : PubMed/NCBI

17 

Orcutt ST, Balentine CJ, Marshall CL, et al: Use of a Pfannenstiel incision in minimally invasive colorectal cancer surgery is associated with a lower risk of wound complications. Tech Coloproctol. 16:127–132. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Greif R, Akça O, Horn EP, et al; Outcomes Research Group. Supplemental perioperative oxygen to reduce the incidence of surgical wound infection. N Engl J Med. 342:161–167. 2000. View Article : Google Scholar

19 

D’Hoore A and Wolthuis AM: Laparoscopic low anterior resection and transanal pull-through for low rectal cancer: a Natural Orifice Specimen Extraction (NOSE) technique. Colorectal Dis. 13(Suppl 7): 28–31. 2011.PubMed/NCBI

20 

Phitayakorn R, Delaney CP, Reynolds HL, et al; International Anastomotic Leak Study Group. Standardized algorithms for management of anastomotic leaks and related abdominal and pelvic abscesses after colorectal surgery. World J Surg. 32:1147–1156. 2008. View Article : Google Scholar : PubMed/NCBI

21 

Eberhardt JM, Kiran RP and Lavery IC: The impact of anastomotic leak and intra-abdominal abscess on cancer-related outcomes after resection for colorectal cancer: a case control study. Dis Colon Rectum. 52:380–386. 2009. View Article : Google Scholar : PubMed/NCBI

22 

Janson M, Björholt I, Carlsson P, et al: Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer. Br J Surg. 91:409–417. 2004. View Article : Google Scholar : PubMed/NCBI

23 

Dowson HM, Gage H, Jackson D, et al: Laparoscopic and open colorectal surgery: a prospective cost analysis. Colorectal Dis. 14:1424–1430. 2012. View Article : Google Scholar : PubMed/NCBI

24 

Delaney CP, Pokala N, Senagore AJ, et al: Is laparoscopic colectomy applicable to patients with body mass index >30? A case-matched comparative study with open colectomy. Dis Colon Rectum. 48:975–981. 2005. View Article : Google Scholar

25 

Sakamoto K, Niwa S, Tanaka M, et al: Influence of obesity on the short-term outcome of laparoscopic colectomy for colorectal cancer. J Minim Access Surg. 3:98–103. 2007. View Article : Google Scholar : PubMed/NCBI

26 

The Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 350:2050–2059. 2004. View Article : Google Scholar

27 

Capussotti L, Massucco P, Muratore A, et al: Laparoscopy as a prognostic factor in curative resection for node positive colorectal cancer: results for a single-institution nonrandomized prospective trial. Surg Endosc. 18:1130–1135. 2004.

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Copy and paste a formatted citation
Spandidos Publications style
Cai Y, Zhou Y, Li Z, Xiang J and Chen Z: Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy. Oncol Lett 6: 1057-1062, 2013.
APA
Cai, Y., Zhou, Y., Li, Z., Xiang, J., & Chen, Z. (2013). Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy. Oncology Letters, 6, 1057-1062. https://doi.org/10.3892/ol.2013.1508
MLA
Cai, Y., Zhou, Y., Li, Z., Xiang, J., Chen, Z."Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy". Oncology Letters 6.4 (2013): 1057-1062.
Chicago
Cai, Y., Zhou, Y., Li, Z., Xiang, J., Chen, Z."Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy". Oncology Letters 6, no. 4 (2013): 1057-1062. https://doi.org/10.3892/ol.2013.1508
Copy and paste a formatted citation
x
Spandidos Publications style
Cai Y, Zhou Y, Li Z, Xiang J and Chen Z: Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy. Oncol Lett 6: 1057-1062, 2013.
APA
Cai, Y., Zhou, Y., Li, Z., Xiang, J., & Chen, Z. (2013). Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy. Oncology Letters, 6, 1057-1062. https://doi.org/10.3892/ol.2013.1508
MLA
Cai, Y., Zhou, Y., Li, Z., Xiang, J., Chen, Z."Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy". Oncology Letters 6.4 (2013): 1057-1062.
Chicago
Cai, Y., Zhou, Y., Li, Z., Xiang, J., Chen, Z."Surgical outcome of laparoscopic colectomy for colorectal cancer in obese patients: A comparative study with open colectomy". Oncology Letters 6, no. 4 (2013): 1057-1062. https://doi.org/10.3892/ol.2013.1508
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