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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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October 2013 Volume 6 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature

  • Authors:
    • Giulia Marvaso
    • Agnese Barone
    • Caterina Vaccaro
    • Vicente Bruzzaniti
    • Silvia Grespi
    • Valerio Scotti
    • Cataldo Bianco
  • View Affiliations / Copyright

    Affiliations: Medical Radiation Oncology Unit, Magna Graecia University and Cancer Center, Germaneto, Catanzaro I-88100, Italy, Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome I-00199, Italy, Malzoni Radiosurgery Center, Neuromed Group, Agropoli, Salerno I-84043, Italy
  • Pages: 897-900
    |
    Published online on: August 2, 2013
       https://doi.org/10.3892/ol.2013.1509
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Abstract

The aims of radiotherapeutic treatment of brain metastases include maintaining neurocognitive function and improvement of survival. Based on these premises, we present a case report in which the role of repeat stereotactic radiosurgery (SRS) was investigated in a patient with a recurrent brain metastasis from non‑small cell lung cancer in the same area as previously treated with radiosurgery. A 40-year-old male caucasian patient was diagnosed with brain metastasis from non-small cell lung cancer (NSCLC) and underwent SRS. The patient developed a recurrence of the disease and a second SRS on the same area was performed. After 8 months, tumor restaging demonstrated a lesion compatible with a recurrence and the patient underwent surgery. Histological diagnosis following surgery revealed only the occurrence of radionecrosis. Radiotherapy was well-tolerated and no grade 3/4 neurological toxicity occurred. To date, no consensus exists on the efficacy of retreatment with SRS. Despite the limited number of studies in this field, in the present case report, we outline the outcomes of this unconventional approach.
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Copy and paste a formatted citation
Spandidos Publications style
Marvaso G, Barone A, Vaccaro C, Bruzzaniti V, Grespi S, Scotti V and Bianco C: Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature. Oncol Lett 6: 897-900, 2013.
APA
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., & Bianco, C. (2013). Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature. Oncology Letters, 6, 897-900. https://doi.org/10.3892/ol.2013.1509
MLA
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., Bianco, C."Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature". Oncology Letters 6.4 (2013): 897-900.
Chicago
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., Bianco, C."Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature". Oncology Letters 6, no. 4 (2013): 897-900. https://doi.org/10.3892/ol.2013.1509
Copy and paste a formatted citation
x
Spandidos Publications style
Marvaso G, Barone A, Vaccaro C, Bruzzaniti V, Grespi S, Scotti V and Bianco C: Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature. Oncol Lett 6: 897-900, 2013.
APA
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., & Bianco, C. (2013). Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature. Oncology Letters, 6, 897-900. https://doi.org/10.3892/ol.2013.1509
MLA
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., Bianco, C."Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature". Oncology Letters 6.4 (2013): 897-900.
Chicago
Marvaso, G., Barone, A., Vaccaro, C., Bruzzaniti, V., Grespi, S., Scotti, V., Bianco, C."Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature". Oncology Letters 6, no. 4 (2013): 897-900. https://doi.org/10.3892/ol.2013.1509
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