Vertebroepidural metastasis of an ethmoid adenocarcinoma: A case report

Mbaye,Maguette; Popa,Claudiu; Signorelli,Francesco; Streichenberger,Nathalie; Cosmidis,Alain; Pozzi,Fabio; Guyotat,Jacques

doi:10.3892/ol.2013.1511

October 2013 Volume 6 Issue 4

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October 2013 Volume 6 Issue 4

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Case Report

Vertebroepidural metastasis of an ethmoid adenocarcinoma: A case report

Authors:
- Maguette Mbaye
- Claudiu Popa
- Francesco Signorelli
- Nathalie Streichenberger
- Alain Cosmidis
- Fabio Pozzi
- Jacques Guyotat
View Affiliations / Copyright

Affiliations: Lyon Civil Hospitals, Pierre Wertheimer Neurological and Neurosurgical Hospital, Service of Neurosurgery D, Lyon 69500, France, Lyon Civil Hospitals, Pierre Wertheimer Neurological and Neurosurgical Hospital, Pathological Anatomy Service, Lyon 69500, France, Croix Rousse Hospital, ENT Service, Lyon 69004, France
Pages: 1007-1010
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Published online on: August 2, 2013

https://doi.org/10.3892/ol.2013.1511
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Abstract

Ethmoid adenocarcinoma is the most frequent ethmoid tumor. To date, only a single case of spinal cord compression resulting from ethmoid adenocarcinoma has been reported. The current case study presents a recent case of vertebroepidural metastasis of an ethmoid adenocarcinoma leading to spinal cord compression. Modern imaging studies, including magnetic resonance imaging (MRI) and 18 fludeoxyglucose positron emission tomography (FDG PET), as well as histological and immunohistochemical analyses, have led to diagnoses of a metastasis of an ethmoid adenocarcinoma, which is a mucinous variant, dedifferentiated when compared to the primary tumor. The present case discusses current diagnostic and treatment protocols of this condition. Since survival rates associated with the primary tumor are improving, the incidence of spinal metastasis of ethmoid carcinomas is likely to increase in the future, therefore requiring appropriate diagnostic and therapeutic management.

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1	de Gabory L, Maunoury A, Maurice-Tison S, Merza Abdulkhaleq H, Darrouzet V, Bébéar JP and Stoll D: Long-term single-center results of management of ethmoid adenocarcinoma: 95 patients over 28 years. Ann Surg Oncol. 17:1127–1134. 2010.PubMed/NCBI
2	Fontana L, Liétin B, Catilina P, Devif C, Féneon B, Martin F, Mom T and Gilain L: Occupational exposure to wood dust and nasal sinus cancer. Ann Otolaryngol Chir Cervicofac. 125:65–71. 2008.(In French).
3	Moreau JJ, Bessede JP, Heurtebise F, Moufid A, Veysset P, Sauvage JP, Rhein B and Roullet B: Adenocarcinoma of the ethmoid sinus in woodworkers. Retrospective study of 25 cases. Neurochirurgie. 43:111–117. 1997.(In French).
4	Roux FX, Pages JC, Nataf F, Devaux B, Laccourreye O, Menard M and Brasnu D: Malignant ethmoid-sphenoidal tumors. 130 cases. Retrospective study. Neurochirurgie. 43:100–110. 1997.(In French).
5	Stoll D, Bébéar JP, Truilhé Y, Darrouzet V and David N: Ethmoid adenocarcinomas: retrospective study of 76 patients. Rev Laryngol Otol Rhinol (Bord). 122:21–29. 2001.PubMed/NCBI
6	Vieillot S, Boisselier P, Aillères N, Hay MH, Dubois JB, Azria D and Fenoglietto P: Paranasal sinus carcinoma. Cancer Radiother. 14(Suppl 1): S52–S60. 2010.(In French).
7	Wen BC, Hussey DH, Clamon GH and Godersky JC: Leptomeningeal carcinomatosis following craniofacial resection of an ethmoid tumor. J Surg Oncol. 49:266–269. 1992. View Article : Google Scholar : PubMed/NCBI
8	George B, Salvan D, Luboinski B, Boissonnet H and Lot G: Malignant tumors of the ethmoid sinuses. A homogenous series of 41 cases operated on by mixed approaches. Neurochirurgie. 43:121–124. 1997.(In French).
9	Herrlinger U, Förschlera H, Kükerb W, Meyermann R, Bamberg M, Dichgans J and Weller M: Leptomeningeal metastasis: survival and prognostic factors in 155 patients. J Neurol Sci. 223:167–178. 2004. View Article : Google Scholar : PubMed/NCBI
10	Newton P and Grennan DM: Ethmoid sinus carcinoma metastasising to the cauda equina: a case report. J Neurol Neurosurg Psychiatry. 46:585–586. 1983. View Article : Google Scholar : PubMed/NCBI
11	Béjot Y, Catteau A, Hervieu M, Giré P, Caillier M, Bénatru I, Osseby GV, Soichot P, Moreau T and Giroud M: Leptomeningeal dissemination after ethmoidal sinus adenocarcinoma surgery: a rare complication. Rev Neurol (Paris). 164:189–193. 2008.(In French).
12	Rogowski J, Fosse S, Dupont J, Poitou L, Valo I and Simon de Kergunic JPS: Adenocarcinoma of the ethmoid with meningeal carcinomatosis. Presse Med. 40:209–211. 2011.(In French).
13	Johns DR and Sweriduk ST: Spinal cord compression due to ethmoid adenocarcinoma. Cancer. 60:1863–1865. 1987. View Article : Google Scholar
14	Wang NP, Zee S, Zarbo RJ, Bacchi CE and Gown AM: Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas. Appl Immunohistochem. 3:99–107. 1995.
15	Baron MP, Cyteval C, Thomas E, Leroux JL, Blotman F and Lamarque JL: Cauda equina syndrome disclosing adenocarcinoma of the ethmoid. J Radiol. 74:363–365. 1993.(In French).
16	Vellin JF, Achim V, Sinardet D, Gabrillargues J, Mom T and Gilain L: Rapidly developing leptomeningeal carcinomatosis following anterior skull base surgery: a case report. Auris Nasus Larynx. 34:565–567. 2007. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Vertebroepidural metastasis of an ethmoid adenocarcinoma: A case report

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