Intracranial choriocarcinoma occurrence in males: Two cases and a review of the literature

Guo,Jianyi; Zhong,Chunlong; Liu,Qiang; Xu,Jiwen; Zheng,Yan; Xu,Siyi; Gao,Yang; Guo,Yang; Wang,Yong; Luo,Qizhong; Jiang,Jiyao

doi:10.3892/ol.2013.1570

November 2013 Volume 6 Issue 5

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November 2013 Volume 6 Issue 5

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Article

Intracranial choriocarcinoma occurrence in males: Two cases and a review of the literature

Authors:
- Jianyi Guo
- Chunlong Zhong
- Qiang Liu
- Jiwen Xu
- Yan Zheng
- Siyi Xu
- Yang Gao
- Yang Guo
- Yong Wang
- Qizhong Luo
- Jiyao Jiang
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, P.R. China, Department of Pathology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, P.R. China
Pages: 1329-1332
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Published online on: September 9, 2013

https://doi.org/10.3892/ol.2013.1570
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Abstract

Choriocarcinomas generally develop in females. Non‑gestational choriocarcinoma in males is extremely rare. The present study describes two cases of young males who were diagnosed with intracranial choriocarcinoma. One case was of an aggressive choriocarcinoma with multiple metastases to the brain, but with an unidentified origin. The patient was admitted in the terminal stage of the cancer. Although a tumor resection was performed, the condition of the patient rapidly deteriorated and chemotherapy was not recommended. The patient succumbed nine days after the surgery. The second case was of a primary ventricular choriocarcinoma. The patient was hospitalized for acute hydrocephalus caused by a mass that was located in the ventricle. Following a tumor resection, the patient underwent a course of whole‑brain and spinal radiotherapy. The patient was followed up for more than half a year and remained in a good condition. The present study describes the two cases and a comprehensive review of the literature that was performed to identify similar studies that document choriocarcinomas in males.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Intracranial choriocarcinoma occurrence in males: Two cases and a review of the literature

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