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Case Report

Extraventricular neurocytoma in pediatric populations: A case report and review of the literature

  • Authors:
    • Lin Han
    • Hongquan Niu
    • Junwen Wang
    • Feng Wan
    • Kai Shu
    • Changshu Ke
    • Ting Lei
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China, Department of Neurosurgery, Center Hospital of Wuhan City, Wuhan, Hubei 430014, P.R. China, Department of Pathology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China
  • Pages: 1397-1405
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    Published online on: September 12, 2013
       https://doi.org/10.3892/ol.2013.1583
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Abstract

Extraventricular neurocytomas (EVNs) are rare neuronal tumors included in the definition of neoplasms in the 2007 World Health Organization classification of tumors of the central nervous system. Although a small case series of EVNs in adults has been previously reported, EVNs in pediatric populations are extremely rare. The current case report presents the clinicopathological features of an EVN in a 2‑year‑old female who presented with nausea and vomiting that had lasted for five days. In addition, an analysis of the imaging features, histology, treatment and prognosis of these reported rare lesions is presented. Immunohistochemically, EVNs are characterized by the robust expression of synaptophysin, but with a lack of oligodendrocyte transcription factor 2, isocitrate dehydrogenase enzyme isoform 1 (IDH1) R132/IDH2 R172 mutations and p53 immunoexpression. The treatment for EVNs in pediatric and adult populations is gross total resection, with post‑operative radiation reserved for subtotal resection or recurrent disease. In addition, drop metastasis must be carefully avoided.
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Copy and paste a formatted citation
Spandidos Publications style
Han L, Niu H, Wang J, Wan F, Shu K, Ke C and Lei T: Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. Oncol Lett 6: 1397-1405, 2013.
APA
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., & Lei, T. (2013). Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. Oncology Letters, 6, 1397-1405. https://doi.org/10.3892/ol.2013.1583
MLA
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., Lei, T."Extraventricular neurocytoma in pediatric populations: A case report and review of the literature". Oncology Letters 6.5 (2013): 1397-1405.
Chicago
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., Lei, T."Extraventricular neurocytoma in pediatric populations: A case report and review of the literature". Oncology Letters 6, no. 5 (2013): 1397-1405. https://doi.org/10.3892/ol.2013.1583
Copy and paste a formatted citation
x
Spandidos Publications style
Han L, Niu H, Wang J, Wan F, Shu K, Ke C and Lei T: Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. Oncol Lett 6: 1397-1405, 2013.
APA
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., & Lei, T. (2013). Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. Oncology Letters, 6, 1397-1405. https://doi.org/10.3892/ol.2013.1583
MLA
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., Lei, T."Extraventricular neurocytoma in pediatric populations: A case report and review of the literature". Oncology Letters 6.5 (2013): 1397-1405.
Chicago
Han, L., Niu, H., Wang, J., Wan, F., Shu, K., Ke, C., Lei, T."Extraventricular neurocytoma in pediatric populations: A case report and review of the literature". Oncology Letters 6, no. 5 (2013): 1397-1405. https://doi.org/10.3892/ol.2013.1583
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