Prognostic value of molecular markers and cytogenetic alterations that characterize breast cancer precursor lesions (Review)

  • Authors:
    • Maurizio Di Bonito
    • Monica Cantile
    • Rossella De Cecio
    • Giuseppina Liguori
    • Gerardo Botti
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  • Published online on: September 17, 2013     https://doi.org/10.3892/ol.2013.1589
  • Pages: 1181-1183
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Abstract

The understanding of the molecular mechanisms that underlie all stages of tumor progression in breast cancer (BC) represents an important goal in the biomedical research of this disease, particularly for the identification of more specific targeted therapies. In this context, BC preinvasive and precursor lesions represent a major dilemma. These lesions are well characterized under the phenotypic and genotypic profile, but it is not clear if they represent obligatory passages of a multistep process determining breast cancer evolution. In fact, the numerous cytogenetic and molecular alterations identified are not always representative of the progression into invasive phenotypes.
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November 2013
Volume 6 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Di Bonito M, Cantile M, De Cecio R, Liguori G and Botti G: Prognostic value of molecular markers and cytogenetic alterations that characterize breast cancer precursor lesions (Review). Oncol Lett 6: 1181-1183, 2013
APA
Di Bonito, M., Cantile, M., De Cecio, R., Liguori, G., & Botti, G. (2013). Prognostic value of molecular markers and cytogenetic alterations that characterize breast cancer precursor lesions (Review). Oncology Letters, 6, 1181-1183. https://doi.org/10.3892/ol.2013.1589
MLA
Di Bonito, M., Cantile, M., De Cecio, R., Liguori, G., Botti, G."Prognostic value of molecular markers and cytogenetic alterations that characterize breast cancer precursor lesions (Review)". Oncology Letters 6.5 (2013): 1181-1183.
Chicago
Di Bonito, M., Cantile, M., De Cecio, R., Liguori, G., Botti, G."Prognostic value of molecular markers and cytogenetic alterations that characterize breast cancer precursor lesions (Review)". Oncology Letters 6, no. 5 (2013): 1181-1183. https://doi.org/10.3892/ol.2013.1589