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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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2014-January Volume 7 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature

  • Authors:
    • Yan Zhou
    • Wen Dong
    • Fangwen Zou
    • Dong-Ai Zhou
    • Jin-An Ma
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China
  • Pages: 140-144
    |
    Published online on: October 29, 2013
       https://doi.org/10.3892/ol.2013.1649
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Abstract

Synovial sarcomas commonly occur in the soft tissue of the extremities, while a primary occurrence in the mediastinum is quite rare. The current study reports the case of an 11‑year‑old male who presented with a neck mass, which computed tomography showed was due to a giant mediastinal mass involving the thyroid gland. The tumor was resected by thoracotomy and diagnosed as monophasic synovial sarcoma by histopathology. The patient received adjuvant combination chemotherapy and radiation therapy following surgery. At the 3-month follow-up, no local tumor recurrence was found. The present case report highlights the significance of recognizing the unusual presentation and clinical manifestation of synovial sarcoma to aid clinical management. Written informed consent was obtained from the patient's family.
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1 

Fletcher CDM, Unni KK and Mertens F: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press; Lyon: 2002

2 

Baptista AM, Camargo OP, Croci AT, et al: Synovial sarcoma of the extremities: prognostic factors for 20 nonmetastatic cases and a new histologic grading system with prognostic significance. Clinics (Sao Paulo). 61:381–386. 2006. View Article : Google Scholar

3 

Korula A, Shah A, Philip MA, Kuruvila K, Pradhip J, Pai MC and Chacko RT: Primary mediastinal synovial sarcoma with transdiaphragmatic extension presenting as a pericardial effusion. Singapore Med J. 50:e26–e28. 2009.PubMed/NCBI

4 

Burt M, Ihde JK, Hajdu SI, Smith JW, Bains MS, Downey R, et al: Primary sarcomas of the mediastinum: results of therapy. J Thorac Cardiovasc Surg. 115:671–680. 1998. View Article : Google Scholar : PubMed/NCBI

5 

Jeganathan R, Davis R, Wilson L, McGuigan J and Sidhu P: Primary mediastinal synovial sarcoma. Ulster Med J. 76:109–111. 2007.

6 

Pal M, Ghosh BN, Roy C and Manna AK: Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature. J Cancer Res Ther. 6:564–566. 2010.PubMed/NCBI

7 

Ravikumar G, Mullick S, Ananthamurthy A and Correa M: Primary synovial sarcoma of the mediastinum: a case report. Case Rep Surg. 2011:6028532011.PubMed/NCBI

8 

Loggos S, Kondrafouris K, Oikonomopoulos G and Mitropoulos F: Large monophasic synovial sarcoma of the mediastinum in a 15-year old boy. Interact Cardiovasc Thorac Surg. 15:909–911. 2012.PubMed/NCBI

9 

Tezcan Y, Koc M, Kocak H and Kaya Y: Primary intrathoracic biphasic synovial sarcoma. Arch Iran Med. 15:331–333. 2012.PubMed/NCBI

10 

Arafah M and Zaidi SN: Poorly differentiated monophasic synovial sarcoma of the mediastinum. Indian J Pathol Microbiol. 54:384–387. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Jang JW, Lee JK, Seo BR and Kim SH: Synovial sarcoma of the posterior neck: a case report and review of literature. J Korean Neurosurg Soc. 47:306–309. 2010. View Article : Google Scholar : PubMed/NCBI

12 

Inagaki H, Nagasaka T, Otsuka T, Sugiura E, Nakashima N and Eimoto T: Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma. Mod Pathol. 13:482–488. 2000. View Article : Google Scholar : PubMed/NCBI

13 

Antonescu CR, Kawai A, Leung DH, Lonardo F, Woodruff JM, Healey JH and Ladanyi M: Strong association of SYT-SSX fusion type and morphologic epithelial differentiation in synovial sarcoma. Diagn Mol Pathol. 9:1–8. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Ferrari A, Gronchi A, Casanova M, et al: Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution. Cancer. 101:627–634. 2004. View Article : Google Scholar

15 

Harb WJ, Luna MA, Patel SR, Ballo MT, Roberts DB and Sturgis EM: Survival in patients with synovial sarcoma of the head and neck: association with tumor location, size, and extension. Head Neck. 29:731–740. 2007. View Article : Google Scholar

16 

Dennison S, Weppler E and Giacoppe G: Primary pulmonary synovial sarcoma: a case report and review of current diagnostic and therapeutic standards. Oncologist. 9:339–342. 2004. View Article : Google Scholar

17 

Balieiro MA, Lopes AJ, Costa BP, Veras GP, Perelson PS, Acatauassú Nunes R and Saito EH: The surprising outcome of a giant primary mediastinal synovial sarcoma treated with neoadjuvant chemotherapy. J Thorac Dis. 5:94–96. 2013.

18 

Sarver AL, Li L and Subramanian S: MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration. Cancer Res. 70:9570–9580. 2010. View Article : Google Scholar : PubMed/NCBI

19 

Randall RL, Schabel KL, Hitchcock Y, Joyner DE and Albritton KH: Diagnosis and management of synovial sarcoma. Curr Treat Options Oncol. 6:449–459. 2005. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Zhou Y, Dong W, Zou F, Zhou D and Ma J: Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature. Oncol Lett 7: 140-144, 2014.
APA
Zhou, Y., Dong, W., Zou, F., Zhou, D., & Ma, J. (2014). Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature. Oncology Letters, 7, 140-144. https://doi.org/10.3892/ol.2013.1649
MLA
Zhou, Y., Dong, W., Zou, F., Zhou, D., Ma, J."Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature". Oncology Letters 7.1 (2014): 140-144.
Chicago
Zhou, Y., Dong, W., Zou, F., Zhou, D., Ma, J."Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature". Oncology Letters 7, no. 1 (2014): 140-144. https://doi.org/10.3892/ol.2013.1649
Copy and paste a formatted citation
x
Spandidos Publications style
Zhou Y, Dong W, Zou F, Zhou D and Ma J: Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature. Oncol Lett 7: 140-144, 2014.
APA
Zhou, Y., Dong, W., Zou, F., Zhou, D., & Ma, J. (2014). Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature. Oncology Letters, 7, 140-144. https://doi.org/10.3892/ol.2013.1649
MLA
Zhou, Y., Dong, W., Zou, F., Zhou, D., Ma, J."Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature". Oncology Letters 7.1 (2014): 140-144.
Chicago
Zhou, Y., Dong, W., Zou, F., Zhou, D., Ma, J."Primary giant mediastinal synovial sarcoma of the neck: A case report and review of the literature". Oncology Letters 7, no. 1 (2014): 140-144. https://doi.org/10.3892/ol.2013.1649
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