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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Article

Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study

  • Authors:
    • K. Aydin
    • S. K. Okutur
    • M. Bozkurt
    • I. Turkmen
    • E. Namal
    • K. Pilanci
    • A. Ozturk
    • Z. Akcali
    • G. Dogusoy
    • O. G. Demir
  • View Affiliations / Copyright

    Affiliations: Department of Medical Oncology, Istanbul Bilim University, Istanbul, Turkey, Department of Pathology, Istanbul Bilim University, Istanbul, Turkey, Department of Pathology, Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey
  • Pages: 255-259
    |
    Published online on: November 6, 2013
       https://doi.org/10.3892/ol.2013.1662
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Abstract

The expression of epidermal growth factor receptor (EGFR) has been linked to clinical outcome in several solid tumors. However, the clinical significance of EGFR (c‑erbB1) in gastric cancer remains unclear. The present study was designed to detect the clinical implications of EGFR in the Turkish population. Paraffin‑embedded tissue microarrays containing gastric cancer tissue were obtained from 30 patients. EGFR expression was detected using immunohistochemistry. The correlation of this biomarker to the clinicopathological features and survival of patients with gastric cancer was studied. The overall positivity rate of EGFR was 63.3%. EGFR expression was significantly correlated with an improved progression‑free survival (PFS) and overall survival (OS) rate (P=0.039 and 0.01, respectively). EGFR expression is a good prognostic marker for patients with gastric cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Aydin K, Okutur SK, Bozkurt M, Turkmen I, Namal E, Pilanci K, Ozturk A, Akcali Z, Dogusoy G, Demir OG, Demir OG, et al: Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study. Oncol Lett 7: 255-259, 2014.
APA
Aydin, K., Okutur, S.K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K. ... Demir, O.G. (2014). Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study. Oncology Letters, 7, 255-259. https://doi.org/10.3892/ol.2013.1662
MLA
Aydin, K., Okutur, S. K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K., Ozturk, A., Akcali, Z., Dogusoy, G., Demir, O. G."Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study". Oncology Letters 7.1 (2014): 255-259.
Chicago
Aydin, K., Okutur, S. K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K., Ozturk, A., Akcali, Z., Dogusoy, G., Demir, O. G."Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study". Oncology Letters 7, no. 1 (2014): 255-259. https://doi.org/10.3892/ol.2013.1662
Copy and paste a formatted citation
x
Spandidos Publications style
Aydin K, Okutur SK, Bozkurt M, Turkmen I, Namal E, Pilanci K, Ozturk A, Akcali Z, Dogusoy G, Demir OG, Demir OG, et al: Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study. Oncol Lett 7: 255-259, 2014.
APA
Aydin, K., Okutur, S.K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K. ... Demir, O.G. (2014). Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study. Oncology Letters, 7, 255-259. https://doi.org/10.3892/ol.2013.1662
MLA
Aydin, K., Okutur, S. K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K., Ozturk, A., Akcali, Z., Dogusoy, G., Demir, O. G."Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study". Oncology Letters 7.1 (2014): 255-259.
Chicago
Aydin, K., Okutur, S. K., Bozkurt, M., Turkmen, I., Namal, E., Pilanci, K., Ozturk, A., Akcali, Z., Dogusoy, G., Demir, O. G."Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study". Oncology Letters 7, no. 1 (2014): 255-259. https://doi.org/10.3892/ol.2013.1662
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