Primary breast T-cell lymphoma, unspecified, treated with autologous peripheral blood stem cell transplantation: 
A case report and literature review

Gao,Qiqi; Zhang,Xiuming; Xiang,Hua; Ren,Guoping; Zheng,Yulong

doi:10.3892/ol.2013.1676

2014-January Volume 7 Issue 1

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2014-January Volume 7 Issue 1

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Case Report

Primary breast T-cell lymphoma, unspecified, treated with autologous peripheral blood stem cell transplantation: A case report and literature review

Authors:
- Qiqi Gao
- Xiuming Zhang
- Hua Xiang
- Guoping Ren
- Yulong Zheng
View Affiliations / Copyright

Affiliations: Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Department of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
Pages: 156-158
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Published online on: November 11, 2013

https://doi.org/10.3892/ol.2013.1676
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Abstract

The current study presents a case of primary T-cell lymphoma (PTBL), unspecified, in a 27‑year‑old female. The patient received chemotherapy [cyclophosphamide, epirubicin, vindesine and prednisolone (CHOP) and VP‑16 plus CHOP (ECHOP)] and autologous peripheral blood stem cell transplantation, however, relapse occurred rapidly. The recurrent tumor exhibited increased levels of karyopyknosis and nuclear fragmentation and a higher Ki67 index compared with the primary tumor. No response to subsequent chemotherapy, including ECHOP and gemcitabine, dexamethasone and cisplatin, was observed. The patient succumbed to PTBL, unspecified, 18 months after the diagnosis. We hypothesize that autologous peripheral blood stem cell transplantation is ineffective for PTBL.

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