Tricholemmal carcinoma of the head and neck region: A report of 15 cases

Feng,Zhien; Zhu,Han‑Guang; Wang,Li Zhen; Zheng,Jia‑Wei; Chen,Wan‑Tao; Zhang,Zhiyuan; Dong,Wei; Qu,Weiguo; Wang,Yan An

doi:10.3892/ol.2013.1726

2014-February Volume 7 Issue 2

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2014-February Volume 7 Issue 2

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Article

Tricholemmal carcinoma of the head and neck region: A report of 15 cases

Authors:
- Zhien Feng
- Han‑Guang Zhu
- Li Zhen Wang
- Jia‑Wei Zheng
- Wan‑Tao Chen
- Zhiyuan Zhang
- Wei Dong
- Weiguo Qu
- Yan An Wang
View Affiliations / Copyright

Affiliations: Department of Oral and Maxillofacial Surgery, School of Stomatology, Peking University, Beijing 100081, P.R. China, Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China, Department of Oral Pathology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China, Department of Oral and Maxillofacial Surgery, Dalian Stomatological Hospital, Dalian University, Dalian, Liaoning 116021, P.R. China
Pages: 423-426
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Published online on: December 4, 2013

https://doi.org/10.3892/ol.2013.1726
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Abstract

Tricholemmal carcinoma is an extremely rare malignancy of the skin, and its biological behavior and management is controversial. The objective of the present study was to investigate the clinicopathological characteristics and management of tricholemmal carcinoma of the head and neck region. The study analyzed 15 patients with tricholemmal carcinoma. Demographic and clinical data were collected, and features associated with the management and prognosis of tricholemmal carcinoma were analyzed. Two of the 15 patients were lost to follow‑up. The results showed that, during the follow‑up period, 5 of the 13 available patients succumbed to the causes of recurrence (n=3), neck lymph node metastasis (n=1) and Parkinson's disease (n=1). No patients developed distant metastasis. The disease‑free survival (DFS) and overall survival (OS) were 31.1±7.8 and 32.9±7.4 months (mean ± SE), respectively, and the DFS and OS rates were 69.2 and 61.5%, respectively. In conclusion, the biological behavior of tricholemmal carcinoma is locoregionally aggressive. The recommended management for head and neck tricholemmal carcinoma is radical resection and neck dissection, and post‑operative radiotherapy may be considered for high‑risk patients.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Tricholemmal carcinoma of the head and neck region: A report of 15 cases

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