|
1
|
Chien CY, Su CY, Hwang CF, Chuang HC,
Hsiao YC, Wu SL and Huang CC: Clinicopathologic significance of
CD105 expression in squamous cell carcinoma of the hypopharynx.
Head Neck. 28:441–446. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Brown JM and Wilson WR: Exploiting tumour
hypoxia in cancer treatment. Nat Rev Cancer. 4:437–447. 2004.
View Article : Google Scholar
|
|
3
|
Wouters BG and Koritzinsky M: Hypoxia
signalling through mTOR and the unfolded protein response in
cancer. Nat Rev Cancer. 8:851–864. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ghosh R, Lipson KL, Sargent KE, Mercurio
AM, Hunt JS, Ron D and Urano F: Transcriptional regulation of
VEGF-A by the unfolded protein response pathway. PLoS ONE.
5:e95752010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Rzymski T, Milani M, Pike L, et al:
Regulation of autophagy by ATF4 in response to severe hypoxia.
Oncogene. 29:4424–4435. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Koumenis C and Wouters BG: ‘Translating’
tumor hypoxia: unfolded protein response (UPR)-dependent and
UPR-independent pathways. Mol Cancer Res. 4:423–436. 2006.
|
|
7
|
Rutkowski DT and Kaufman RJ: A trip to the
ER: coping with stress. Trends Cell Bio. 14:20–28. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Grkovic S, O’Reilly VC, Han S, Hong M,
Baxter RC and Firth SM: IGFBP-3 binds GRP78, stimulates autophagy
and promotes the survival of breast cancer cells exposed to adverse
microenvironments. Oncogene. 32:2412–2420. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kandala PK and Srivastava SK: Regulation
of macroautophagy in ovarian cancer cells in vitro and in vivo by
controlling glucose regulatory protein 78 and AMPK. Oncotarget.
3:435–449. 2012.PubMed/NCBI
|
|
10
|
de Ridder G, Ray R, Misra UK and Pizzo SV:
Modulation of the unfolded protein response by GRP78 in prostate
cancer. Methods Enzymol. 489:245–257. 2011.PubMed/NCBI
|
|
11
|
Jemal A, Siegel R, Ward E, Hao Y, Xu J,
Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin.
58:71–96. 2008. View Article : Google Scholar
|
|
12
|
Sun Q, Li X, Lu X and Di B: Cancer stem
cells may be mostly maintained by fluctuating hypoxia. Med
Hypotheses. 76:471–473. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Huang LW, Lin CY, Lee CC, Liu TZ and Jeng
CJ: Overexpression of GRP78 is associated with malignant
transformation in epithelial ovarian tumors. Appl Immunohistochem
Mol Morphol. 20:381–385. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kuroda K, Horiguchi A, Asano T, et al:
Glucose-regulated protein 78 positivity as a predictor of poor
survival in patients with renal cell carcinoma. Urol Int.
87:450–456. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Koumenis C, Bi M, Ye J, Feldman D and
Koong AC: Hypoxia and the unfolded protein response. Methods
Enzymol. 435:275–293. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Krivoruchko A and Storey KB: Activation of
the unfolded protein response during anoxia exposure in the turtle
Trachemys scripta elegans. Mol Cell Biochem. 374:91–103.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Pyrko P, Schönthal AH, Hofman FM, Chen TC
and Lee AS: The unfolded protein response regulator GRP78/BiP as a
novel target for increasing chemosensitivity in malignant gliomas.
Cancer Res. 67:9809–9816. 2007. View Article : Google Scholar
|
|
18
|
Healy SJ, Gorman AM, Mousavi-Shafaei P,
Gupta S and Samali A: Targeting the endoplasmic reticulum-stress
response as an anticancer strategy. Eur J Pharmacol. 625:234–246.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Fu Y, Li J and Lee AS: GRP78/BiP inhibits
endoplasmic reticulum BIK and protects human breast cancer cells
against estrogen starvation-induced apoptosis. Cancer Res.
67:3734–3740. 2007. View Article : Google Scholar
|
|
20
|
Zhou H, Zhang Y, Fu Y, Chan L and Lee AS:
Novel mechanism of anti-apoptotic function of 78-kDa
glucose-regulated protein (GRP78): endocrine resistance factor in
breast cancer, through release of B-cell lymphoma 2 (BCL-2) from
BCL-2-interacting killer (BIK). J Biol Chem. 286:25687–25696. 2011.
View Article : Google Scholar
|
|
21
|
McCullough KD, Martindale JL, Klotz LO, Aw
TY and Holbrook NJ: Gadd153 sensitizes cells to endoplasmic
reticulum stress by down-regulating Bcl2 and perturbing the
cellular redox state. Mol Cell Biol. 21:1249–1259. 2001. View Article : Google Scholar
|
|
22
|
Dong D, Ni M, Li J, et al: Critical role
of the stress chaperone GRP78/BiP in tumor proliferation, survival,
and tumor angiogenesis in transgene-induced mammary tumor
development. Cancer Res. 68:498–505. 2008. View Article : Google Scholar : PubMed/NCBI
|