|
1
|
World Health Organization. World health
statistics. WHO Press; Switzerland: pp. 1–177. 2010
|
|
2
|
Caterina MJ, Schumacher MA, Tominaga M,
Rosen TA, Levine JD and Julius D: The capsaicin receptor: a
heat-activated ion channel in the pain pathway. Nature.
389:816–824. 1997. View
Article : Google Scholar
|
|
3
|
Winter J, Bevan S and Campbell EA:
Capsaicin and pain mechanisms. Br J Anaesth. 75:157–168. 1995.
View Article : Google Scholar
|
|
4
|
McCarthy GM and McCarty DJ: Effect of
topical capsaicin in the therapy of painful osteoarthritis of the
hands. J Rheumatol. 19:604–607. 1992.PubMed/NCBI
|
|
5
|
Matucci-Cerinic M, McCarthy G, Lombardi A,
Pignone A and Partsch G: Neurogenic influences in arthritis. J
Rheumatol. 22:1447–1449. 1995.PubMed/NCBI
|
|
6
|
Sindrup SH and Jensen TS: Efficacy of
pharmacological treatments of neuropathic pain: an update and
effect related to mechanism of drug action. Pain. 83:389–400. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Low PA, Opfer-Gehrking TL, Dyck PJ, Litchy
WJ and O’Brien PC: Double-blind, placebo-controlled study of the
application of capsaicin cream in chronic distal painful
polyneuropathy. Pain. 62:163–168. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ross DR and Varipapa RJ: Treatment of
painful diabetic neuropathy with topical capsaicin. N Engl J Med.
321:474–475. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Szallasi A and Blumberg PM: Vanilloid
(Capsaicin) receptors and mechanisms. Pharmacol Rev. 51:159–212.
1999.
|
|
10
|
Huang SP, Chen JC, Wu CC, et al:
Capsaicin-induced apoptosis in human hepatoma HepG2 cells.
Anticancer Res. 29:165–174. 2009.PubMed/NCBI
|
|
11
|
Chow J, Norng M, Zhang J and Chai J: TRPV6
mediates capsaicin-induced apoptosis in gastric cancer
cells-mechanisms behind a possible new ‘hot’ cancer treatment.
Biochim Biophys Acta. 1773:565–576. 2007.PubMed/NCBI
|
|
12
|
Sánchez AM, Malagarie-Cazenave S, Olea N,
Vara D, Chiloeches A and Díaz-Laviada I: Apoptosis induced by
capsaicin in prostate PC-3 cells involves ceramide accumulation,
neutral sphingomyelinase, and JNK activation. Apoptosis.
12:2013–2024. 2007.
|
|
13
|
Chou CC, Wu YC, Wang YF, Chou MJ, Kuo SJ
and Chen DR: Capsaicin-induced apoptosis in human breast cancer
MCF-7 cells through caspase independent pathway. Oncol Rep.
21:665–671. 2009.PubMed/NCBI
|
|
14
|
Amantini C, Mosca M, Nabissi M, et al:
Capsaicin-induced apoptosis of glioma cells is mediated by TRPV1
vanilloid receptor and requires p38 MAPK activation. J Neurochem.
102:977–990. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ito K, Nakazato T, Yamato K, et al:
Induction of apoptosis in leukemic cells by homovainillic acid
derívate, capsaicin, through oxidative stress: implication of
phosphorylation of p53 at Ser-15 residue by reactive oxygen
species. Cancer Res. 64:1071–1078. 2004.
|
|
16
|
Kim YM, Hwang JT, Kwak DW, Lee YK and Park
OJ: Involvement of AMPK signaling cascade in capsaicin-induced
apoptosis of HT-29 colon cancer cells. Ann NY Acad Sci.
1095:496–503. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Surh YJ, Lee E and Lee JM: Chemoprotective
properties of some pungent ingredients present in red pepper and
ginger. Mutat Res. 402:259–267. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Surh YJ, Lee RC, Park KK, Mayne ST, Liem A
and Miller JA: Chemoprotective effects of capsaicin and diallyl
sulfide against mutagenesis or tumorigenesis by vinyl carbamate and
N-nitrosodimethylamine. Carcinogenesis. 16:2467–2471. 1995.
View Article : Google Scholar
|
|
19
|
Gil YG and Kang MK: Capsaicin induces
apoptosis and terminal differentiation in human glioma A172 cells.
Life Sci. 82:997–1003. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Appendino G: Capsaicin and capsaicinoids.
Modern Alkaloids: Structure, Isolation, Synthesis and Biology.
Fattorusso E and Taglialatela-Scafati O: Wiley-VCH; Weinheim,
Germany: pp. 73–109. 2008
|
|
21
|
Appendino G, De Petrocellis L, Trevisani
M, et al: Development of the first ultra-potent “capsaicinoid”
agonist at transient receptor potential vanilloid type 1 (TRPV1)
channels and its therapeutic potential. J Pharmacol Exp Ther.
312:561–570. 2005.
|
|
22
|
Appendino G, Minassi A, Morello AS, De
Petrocellis L and Di Marzo V: N-Acylvanillamides: development of an
expeditious synthesis and discovery of new acyl templates for
powerful activation of the vanilloid receptor. J Med Chem.
45:3739–3745. 2002. View Article : Google Scholar
|
|
23
|
Voets T, Droogmans G, Wissenbach U,
Janssens A, Flockerzi V and Nilius B: The principle of
temperature-dependent gating in cold- and heat-sensitive TRP
channels. Nature. 430:748–754. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Castillo E, Regla I, Demare P,
Luviano-Jardón A and López-Munguía A: Efficient chemoenzymatic
synthesis of phenylacetylrinvanil: an ultrapotent capsaicinoid.
Synlett. 18:2869–2873. 2008. View Article : Google Scholar
|
|
25
|
Vichai V and Kirtikara K: Sulforhodamine B
colorimetric assay for cytotoxicity screening. Nat Protoc.
1:1112–1116. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Strober W: Trypan blue exclusion test of
cell viability. Curr Protoc Immunol (Appendix 3). Appendix 3B.
2001. View Article : Google Scholar
|
|
27
|
Gross-Bellard M, Oudet P and Chambon P:
Isolation of high-molecular-weight DNA from mammalian cells. Eur J
Biochem. 36:32–38. 1973. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Morré DJ, Chueh PJ and Morré DM: Capsaicin
inhibits preferentially the NADH oxidase and growth of transformed
cells in culture. Proc Natl Acad Sci USA. 92:1831–1835.
1995.PubMed/NCBI
|
|
29
|
Morré DJ, Sun E, Geilen C, et al:
Capsaicin inhibits plasma membrane NADH oxidase and growth of human
and mouse melanoma lines. Eur J Cancer. 32A:1995–2003. 1996.
|
|
30
|
Call JA, Eckhardt SG and Camidge DR:
Targeted manipulation of apoptosis in cancer treatment. Lancet
Oncol. 9:1002–1011. 2008. View Article : Google Scholar
|
|
31
|
Fenech M: Cytokinesis-block micronucleus
cytome assay. Nat Protoc. 1084–1104. 2007. View Article : Google Scholar
|
|
32
|
Oyagbemi AA, Saba AB and Azeez OI:
Capsaicin: a novel chemopreventive molecule and its underlying
molecular mechanisms of action. Indian J Cancer. 47:53–58. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Griffin AM, Butow PN, Coates AS, et al: On
the receiving end V: Patient perceptions of the side effects of
cancer chemotherapy in 1993. Ann Oncol. 7:189–195. 1996. View Article : Google Scholar
|
|
34
|
Carey MP and Burish TG: Etiology and
treatment of the psychological side effects associated with cancer
chemotherapy: a critical review and discussion. Psychol Bull.
104:307–325. 1988. View Article : Google Scholar
|
