Non‑surgical treatment of canine oral malignant melanoma: A case study of the application of complementary alternative medicine

Itoh,Hiroyasu; Mukaiyama,Toshiyuki; Goto,Takahiro; Hata,Keishi; Azuma,Kazuo; Tsuka,Takashi; Osaki,Tomohiro; Imagawa,Tomohiro; Okamoto,Yoshiharu

doi:10.3892/ol.2014.2041

Non‑surgical treatment of canine oral malignant melanoma: A case study of the application of complementary alternative medicine

Authors:
- Hiroyasu Itoh
- Toshiyuki Mukaiyama
- Takahiro Goto
- Keishi Hata
- Kazuo Azuma
- Takashi Tsuka
- Tomohiro Osaki
- Tomohiro Imagawa
- Yoshiharu Okamoto
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Affiliations: Kamo Animal Clinic, Saijyocho, Higashihiroshima, Hiroshima 739-0044, Japan, Sakamoto Bio Co. Ltd., Yuuwa-Memeki, Akita 010‑1233, Japan, Institute of Food and Brewing, Akita Prefectural Agricultural, Forestry and Fisheries Research Center, Arayamachi, Akita 010-1623, Japan, Faculty of Agriculture, Tottori University, Koyama-Minami, Tottori 680-8553, Japan
Published online on: April 7, 2014 https://doi.org/10.3892/ol.2014.2041
Pages: 1829-1830

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Abstract

This report describes a dog with a clinical stage III oral malignant melanoma that was treated with complementary alternative medicine (CAM). The CAM included high temperature hyperthermia, dendritic cell therapy and lupeol injections. Surgery, radiation and chemotherapy were not performed. Two months after the start of treatment, the tumor disappeared and after six months, the follow‑up examinations revealed no recurrence or metastasis of the tumor. Quality of life (QOL) of the dog was maintained; therefore, the application of CAM may be an effective treatment for canine oral malignant melanoma. The effective application of CAM has the potential to prolong life and maintain an excellent QOL for pets.

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