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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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June-2014 Volume 7 Issue 6

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Case Report

Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review

  • Authors:
    • Zunguo Du
    • Yin Wang
    • Ping Zhu
    • Haiyan Leng
    • Feng Tang
    • Xiaoping Xu
    • Zi Chen
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China, Department of Neuropathology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China, Department of Hematology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China
  • Pages: 1881-1884
    |
    Published online on: April 9, 2014
       https://doi.org/10.3892/ol.2014.2052
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Abstract

Primary testicular lymphoma (PTL) accounts for ~1% of all non‑Hodgkin's lymphomas and has a marked tendency for systemic relapse. The current study presents a unique case of testicular diffuse large B‑cell lymphoma of non‑germinal center B‑cell subtype, with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse. Subcutaneous relapse and subsequent brain relapse are extremely rare signs of PTL dissemination. The patient received methotrexate‑based combined chemotherapy and achieved a partial response. This case presents a rare pattern of treatment failure in this malignant clinical entity.
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Copy and paste a formatted citation
Spandidos Publications style
Du Z, Wang Y, Zhu P, Leng H, Tang F, Xu X and Chen Z: Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review. Oncol Lett 7: 1881-1884, 2014.
APA
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., & Chen, Z. (2014). Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review. Oncology Letters, 7, 1881-1884. https://doi.org/10.3892/ol.2014.2052
MLA
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., Chen, Z."Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review". Oncology Letters 7.6 (2014): 1881-1884.
Chicago
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., Chen, Z."Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review". Oncology Letters 7, no. 6 (2014): 1881-1884. https://doi.org/10.3892/ol.2014.2052
Copy and paste a formatted citation
x
Spandidos Publications style
Du Z, Wang Y, Zhu P, Leng H, Tang F, Xu X and Chen Z: Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review. Oncol Lett 7: 1881-1884, 2014.
APA
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., & Chen, Z. (2014). Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review. Oncology Letters, 7, 1881-1884. https://doi.org/10.3892/ol.2014.2052
MLA
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., Chen, Z."Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review". Oncology Letters 7.6 (2014): 1881-1884.
Chicago
Du, Z., Wang, Y., Zhu, P., Leng, H., Tang, F., Xu, X., Chen, Z."Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review". Oncology Letters 7, no. 6 (2014): 1881-1884. https://doi.org/10.3892/ol.2014.2052
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