Pituitary adenoma with gangliocytoma: Report of two cases

Chen,Danqi; Xu,Jian; Zhong,Ping; Huang,Xiang; Xu,Ming

doi:10.3892/ol.2014.2183

Pituitary adenoma with gangliocytoma: Report of two cases

Authors:
- Danqi Chen
- Jian Xu
- Ping Zhong
- Xiang Huang
- Ming Xu
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Affiliations: Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China
Published online on: May 27, 2014 https://doi.org/10.3892/ol.2014.2183
Pages: 781-784

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Abstract

Worldwide, cases of pituitary adenoma with gangliocytoma are rarely reported. The current study reports the cases of two 47‑year‑old females who presented with masses in the sellar region following a general examination and radiological imaging. The two patients underwent sellar region tumor resection via the trans‑naso‑sphenoid approach. The histopathological examination confirmed the diagnosis of a hormone‑free pituitary adenoma with gangliocytoma. The two patients were in good condition and experienced no specific discomfort subsequent to the follow‑up after surgery. Gangliocytoma is a slowly growing and non‑metastasizing tumor. A biopsy is required to differentiate a gangliocytoma from a malignant neuroblastoma, and excision is usually curative.

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