Submucosal small‑cell neuroendocrine carcinoma of the larynx detected using 18F‑fluorodeoxyglucose positron emission tomography/computed tomography: A case report and review of the literature

Ying,Hong‑Fang; Bao,Yang‑Yang; Zhou,Shui‑Hong; Chai,Liang; Zhao,Kui; Wu,Ting‑Ting

doi:10.3892/ol.2014.2246

Submucosal small‑cell neuroendocrine carcinoma of the larynx detected using 18F‑fluorodeoxyglucose positron emission tomography/computed tomography: A case report and review of the literature

Authors:
- Hong‑Fang Ying
- Yang‑Yang Bao
- Shui‑Hong Zhou
- Liang Chai
- Kui Zhao
- Ting‑Ting Wu
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Affiliations: Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, The PET Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
Published online on: June 12, 2014 https://doi.org/10.3892/ol.2014.2246
Pages: 1065-1069

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Abstract

A 67‑year‑old male presented with a metastatic carcinoma in the right side of the neck from an unknown primary site. 18F‑fluorodeoxyglucose (FDG) positron emission tomography/computed tomography showed increased 18F‑FDG uptake in the right larynx and right neck lymph nodes. A smooth lesion was identified in the submucosa of the right supraglottic region via a suspension laryngoscopy under general anaesthesia. A biopsy was performed and a frozen section revealed a small‑cell (SC) carcinoma. A total laryngectomy and bilateral neck dissection were performed simultaneously, and the pathological results demonstrated a SC neuroendocrine carcinoma. The patient received chemo‑radiotherapy postoperatively, however, succumbed due to distant metastasis one year following surgery.

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