Osteosarcoma arising from the parapharyngeal space: A case report

Hoshi,Manabu; Takada,Jun; Oebisu,Naoto; Nakamura,Hiroaki

doi:10.3892/ol.2014.2265

September-2014 Volume 8 Issue 3

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September-2014 Volume 8 Issue 3

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Case Report

Osteosarcoma arising from the parapharyngeal space: A case report

Authors:
- Manabu Hoshi
- Jun Takada
- Naoto Oebisu
- Hiroaki Nakamura
View Affiliations / Copyright

Affiliations: Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka 545‑8585, Japan
Pages: 1240-1242
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Published online on: June 18, 2014

https://doi.org/10.3892/ol.2014.2265
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Abstract

The current study presents a rare case of osteoblastic osteosarcoma arising from an extremely rare site, namely, the parapharyngeal space. To the best of our knowledge, this is the first study of computed tomography (CT) and magnetic resonance imaging (MRI) of an osteosarcoma in the parapharyngeal space with pathological correlation. A 56‑year‑old male presented with a mass of the right facial region. CT and MRI showed a heterogeneous mass, with ossification or calcification, occupying the parapharyngeal space. Open biopsy revealed an osteoblastic osteosarcoma containing calcified malignant osteoid. Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan). Systemic chemotherapy and radiotherapy were administered to the patient for palliation. The patient was alive at the 24‑month follow‑up subsequent to this treatment. Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space. The present study also briefly discusses osteosarcoma of the parapharyngeal space.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Osteosarcoma arising from the parapharyngeal space: A case report

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Abstract

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