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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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September-2014 Volume 8 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Case Report

Epithelioid angiosarcoma of the kidney: A case report and literature review

  • Authors:
    • Hongyun Liu
    • Xingang Huang
    • Hua Chen
    • Xuechun Wang
    • Lei Chen

  • View Affiliations / Copyright

    Affiliations: Department of Pathology, Municipal Hospital, Qingdao, Shandong 266071, P.R. China, Department of Radiology, Municipal Hospital, Qingdao, Shandong 266071, P.R. China, Department of Physiology, Qingdao University Medical College, Qingdao, Shandong 266071, P.R. China
  • Pages: 1155-1158
    |
    Published online on: June 26, 2014
       https://doi.org/10.3892/ol.2014.2292
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Abstract

Epithelioid angiosarcoma (EAS) is a rare disease which presents a great diagnostic challenge. The present study reports a case of EAS in the kidney in a 75‑year‑old male who presented with gross hematuria. An abdominal computed tomography scan revealed space‑occupying lesions of the right kidney and renal cell carcinoma was suspected. Histological examination of the resected specimens showed pleomorphic epithelioid cells with vesicular nuclei, prominent nucleoli and eosinophilic cytoplasm that lined irregular vascular spaces. Immunohistochemical staining revealed that the tumor cells were positive for AE1/AE3, cytokeratin (CK) 7, vimentin, cluster of differentiation (CD) 31 and E‑cadherin, but showed no staining for CD10, CD34, factor VIII, CK20, carcinoembryonic antigen or desmin. Based on the histopathological and immunohistochemical findings, the patient was diagnosed with epithelioid angiosarcoma. Postoperative radiation therapy was administered and no recurrence was observed six months after surgery.
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1 

Fletcher CDM: Diagnostic Histopathology of Tumors. 1. 3rd edition. Elsevier; Limited, Philadelphia, PA: pp. 66–67. 2007

2 

Fletcher CDM, Beham A, Bekir S, Clarke AM and Marler NJ: Epithelioid angiosarcoma of deep soft tissue: a distinctive tumor readily mistaken for an epithelial neoplasm. Am J Surg Pathol. 15:915–924. 1991.

3 

Costantini R, Di Bartolomeo N, Francomano F, Angelucci D and Innocenti P: Epithelioid angiosarcoma of the gallbladder: case report. J Gastrointest Surg. 9:822–825. 2005.

4 

Olawaiye AB, Morgan JA, Goodman A, Fuller AF Jr and Penson RT: Epithelioid angiosarcoma of the uterus: a review of management. Arch Gynecol Obstet. 278:401–404. 2008.

5 

Agaimy A, Kirsche H, Semrau S, Iro H and Hartmann A: Cytokeratin-positive epithelioid angiosarcoma presenting in the tonsil: a diagnostic challenge. Hum Pathol. 43:1142–1147. 2012.

6 

Meis-Kindblom JM and Kindblom LG: Angiosarcoma of soft tissue: a study of 80 cases. Am J Surg Pathol. 22:683–697. 1998.

7 

Singh C, Xie L, Schmechel SC, Manivel JC and Pambuccian SE: Epithelioid angiosarcoma of the kidney: a diagnostic dilemma in fine-needle aspiration cytology. Diagn Cytopathol. 40(Suppl 2): E131–E139. 2012.

8 

Brown JG, Folpe AL, Rao P, et al: Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases. Am J Surg Pathol. 34:942–949. 2010.

9 

Jennings TA, Peterson L, Axiotis CA, et al: Angiosarcoma associated with foreign body material. A report of three cases. Cancer. 62:2436–2444. 1988.

10 

Hart J and Mandavilli S: Epithelioid angiosarcoma: a brief diagnostic review and differential diagnosis. Arch Pathol Lab Med. 135:268–272. 2011.

11 

Weed BR and Folpe AL: Cutaneous CD30-positive epithelioid angiosarcoma following breast-conserving therapy and irradiation: a potential diagnostic pitfall. Am J Dermatopathol. 30:370–372. 2008.

12 

Miettinen M, Fanburg-Smith JC, Virolainen M, Shmookler BM and Fetsch JF: Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis. Hum Pathol. 30:934–942. 1999.

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Copy and paste a formatted citation
Spandidos Publications style
Liu H, Huang X, Chen H, Wang X and Chen L: Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncol Lett 8: 1155-1158, 2014.
APA
Liu, H., Huang, X., Chen, H., Wang, X., & Chen, L. (2014). Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncology Letters, 8, 1155-1158. https://doi.org/10.3892/ol.2014.2292
MLA
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8.3 (2014): 1155-1158.
Chicago
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8, no. 3 (2014): 1155-1158. https://doi.org/10.3892/ol.2014.2292
Copy and paste a formatted citation
x
Spandidos Publications style
Liu H, Huang X, Chen H, Wang X and Chen L: Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncol Lett 8: 1155-1158, 2014.
APA
Liu, H., Huang, X., Chen, H., Wang, X., & Chen, L. (2014). Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncology Letters, 8, 1155-1158. https://doi.org/10.3892/ol.2014.2292
MLA
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8.3 (2014): 1155-1158.
Chicago
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8, no. 3 (2014): 1155-1158. https://doi.org/10.3892/ol.2014.2292
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