Epithelioid angiosarcoma of the kidney: A case report and literature review

  • Authors:
    • Hongyun Liu
    • Xingang Huang
    • Hua Chen
    • Xuechun Wang
    • Lei Chen
  • View Affiliations

  • Published online on: June 26, 2014     https://doi.org/10.3892/ol.2014.2292
  • Pages: 1155-1158
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Abstract

Epithelioid angiosarcoma (EAS) is a rare disease which presents a great diagnostic challenge. The present study reports a case of EAS in the kidney in a 75‑year‑old male who presented with gross hematuria. An abdominal computed tomography scan revealed space‑occupying lesions of the right kidney and renal cell carcinoma was suspected. Histological examination of the resected specimens showed pleomorphic epithelioid cells with vesicular nuclei, prominent nucleoli and eosinophilic cytoplasm that lined irregular vascular spaces. Immunohistochemical staining revealed that the tumor cells were positive for AE1/AE3, cytokeratin (CK) 7, vimentin, cluster of differentiation (CD) 31 and E‑cadherin, but showed no staining for CD10, CD34, factor VIII, CK20, carcinoembryonic antigen or desmin. Based on the histopathological and immunohistochemical findings, the patient was diagnosed with epithelioid angiosarcoma. Postoperative radiation therapy was administered and no recurrence was observed six months after surgery.
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September-2014
Volume 8 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Liu H, Huang X, Chen H, Wang X and Chen L: Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncol Lett 8: 1155-1158, 2014
APA
Liu, H., Huang, X., Chen, H., Wang, X., & Chen, L. (2014). Epithelioid angiosarcoma of the kidney: A case report and literature review. Oncology Letters, 8, 1155-1158. https://doi.org/10.3892/ol.2014.2292
MLA
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8.3 (2014): 1155-1158.
Chicago
Liu, H., Huang, X., Chen, H., Wang, X., Chen, L."Epithelioid angiosarcoma of the kidney: A case report and literature review". Oncology Letters 8, no. 3 (2014): 1155-1158. https://doi.org/10.3892/ol.2014.2292